CRCGN009_HEPG2_24H:B23 Gene Set
Genes
49 genes differentially expressed following the CRCGN009_HEPG2_24H:B23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STIMATE
|
STIM activating enhancer
|
6.50771
|
|
E2F2
|
E2F transcription factor 2
|
5.59696
|
|
CCDC92
|
coiled-coil domain containing 92
|
4.94745
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.61454
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
4.2145
|
|
MAP7
|
microtubule-associated protein 7
|
3.75395
|
|
MEF2C
|
myocyte enhancer factor 2C
|
3.50081
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.44672
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
3.19343
|
|
SHB
|
Src homology 2 domain containing adaptor protein B
|
3.15821
|
|
CHEK2
|
checkpoint kinase 2
|
3.06164
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.05907
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.97015
|
|
MAMLD1
|
mastermind-like domain containing 1
|
2.89823
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.72876
|
|
LCN2
|
lipocalin 2
|
2.72637
|
|
GPATCH8
|
G patch domain containing 8
|
2.71248
|
|
SNX7
|
sorting nexin 7
|
2.63837
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.55322
|
|
KIFBP
|
kinesin family binding protein
|
2.28729
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.28264
|
|
PRR15L
|
proline rich 15-like
|
2.25826
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.22874
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.11353
|
|
RRAGA
|
Ras-related GTP binding A
|
2.11018
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.10282
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLR4
|
toll-like receptor 4
|
-5.81298
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-5.5263
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.16822
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.54444
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-3.35318
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.10074
|
|
GNAS
|
GNAS complex locus
|
-2.9804
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-2.94689
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.87213
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-2.85944
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-2.80453
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.74968
|
|
NCK1
|
NCK adaptor protein 1
|
-2.74452
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-2.72637
|
|
RHEB
|
Ras homolog enriched in brain
|
-2.67103
|
|
LDHD
|
lactate dehydrogenase D
|
-2.60419
|
|
CAB39
|
calcium binding protein 39
|
-2.5759
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.55095
|
|
HYOU1
|
hypoxia up-regulated 1
|
-2.53825
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.41125
|
|
RNF167
|
ring finger protein 167
|
-2.38567
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.2722
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-2.02978
|
