| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tolbutamide 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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55 genes differentially expressed following the CRCGN009_HEPG2_24H:B24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 5.29903 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 5.17671 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 4.94972 |
| UBQLN2 | ubiquilin 2 | 4.92979 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.80704 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.42543 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 4.40521 |
| SFTPB | surfactant protein B | 3.59935 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 3.45752 |
| FZD7 | frizzled class receptor 7 | 3.28058 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.19498 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 3.1197 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.01192 |
| PFKL | phosphofructokinase, liver | 2.97034 |
| CRTAP | cartilage associated protein | 2.90534 |
| CDK19 | cyclin-dependent kinase 19 | 2.73223 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.65734 |
| MAP7 | microtubule-associated protein 7 | 2.63663 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.54212 |
| CHN1 | chimerin 1 | 2.44947 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 2.44041 |
| FPGS | folylpolyglutamate synthase | 2.40572 |
| NEMF | nuclear export mediator factor | 2.36869 |
| ZNF589 | zinc finger protein 589 | 2.28975 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.1713 |
| DNAAF2 | dynein, axonemal, assembly factor 2 | 2.08335 |
| CCNF | cyclin F | 2.0822 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TUBB6 | tubulin, beta 6 class V | -5.4567 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.32079 |
| NRIP1 | nuclear receptor interacting protein 1 | -5.23986 |
| PLK1 | polo-like kinase 1 | -5.15135 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.09023 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.04954 |
| LDHD | lactate dehydrogenase D | -3.81847 |
| ZNF586 | zinc finger protein 586 | -3.30765 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | -2.88361 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.71338 |
| TLR4 | toll-like receptor 4 | -2.65144 |
| INHA | inhibin, alpha | -2.50402 |
| TWF2 | twinfilin actin binding protein 2 | -2.40545 |
| STOM | stomatin | -2.40054 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 | -2.37698 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.30568 |
| RNF167 | ring finger protein 167 | -2.27549 |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase | -2.27251 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -2.22932 |
| HAND1 | heart and neural crest derivatives expressed 1 | -2.17067 |
| SNAI2 | snail family zinc finger 2 | -2.12633 |
| CA2 | carbonic anhydrase II | -2.12626 |
| FANCG | Fanconi anemia, complementation group G | -2.07605 |
| GRB7 | growth factor receptor-bound protein 7 | -2.04657 |
| NPY1R | neuropeptide Y receptor Y1 | -2.02631 |
| DOCK6 | dedicator of cytokinesis 6 | -2.02335 |
| ZNF629 | zinc finger protein 629 | -2.0086 |
| PRSS8 | protease, serine, 8 | -2.00784 |
