| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tetrakis(hydroxymethyl)phos-phonium chloride 10.05 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
51 genes differentially expressed following the CRCGN009_HEPG2_24H:C03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 10.0 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.07564 |
| GPATCH8 | G patch domain containing 8 | 3.7759 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.55479 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.5442 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.53829 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.50734 |
| MAP7 | microtubule-associated protein 7 | 3.36187 |
| LCN2 | lipocalin 2 | 3.33686 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 3.32309 |
| DIPK1A | divergent protein kinase domain 1A | 3.03737 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.87359 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.75535 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.74003 |
| KLHL9 | kelch-like family member 9 | 2.46388 |
| PLSCR3 | phospholipid scramblase 3 | 2.43301 |
| FZD7 | frizzled class receptor 7 | 2.37259 |
| ALDOC | aldolase C, fructose-bisphosphate | 2.363 |
| KLHL21 | kelch-like family member 21 | 2.25543 |
| CHEK2 | checkpoint kinase 2 | 2.25011 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 2.24457 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | 2.24048 |
| MTERF3 | mitochondrial transcription termination factor 3 | 2.22936 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.1781 |
| CTSL | cathepsin L | 2.15069 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.13212 |
| TEX10 | testis expressed 10 | 2.08318 |
| ABHD6 | abhydrolase domain containing 6 | 2.04324 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | -5.92678 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.83917 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -5.43642 |
| CDC20 | cell division cycle 20 | -3.99382 |
| ADI1 | acireductone dioxygenase 1 | -3.39267 |
| CDC25B | cell division cycle 25B | -3.07675 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.03782 |
| TSPAN4 | tetraspanin 4 | -2.90909 |
| GNAS | GNAS complex locus | -2.81388 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.51485 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.4792 |
| PCNA | proliferating cell nuclear antigen | -2.46684 |
| CHMP4B | charged multivesicular body protein 4B | -2.42265 |
| PDGFC | platelet derived growth factor C | -2.37135 |
| TOR1A | torsin family 1, member A (torsin A) | -2.2651 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.26357 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.26317 |
| TXNDC9 | thioredoxin domain containing 9 | -2.24742 |
| TLCD3A | TLC domain containing 3A | -2.22831 |
| CCNH | cyclin H | -2.20075 |
| ZNF134 | zinc finger protein 134 | -2.12021 |
| SLC35F2 | solute carrier family 35, member F2 | -2.09418 |
| SESN1 | sestrin 1 | -2.03591 |
