CRCGN009_HEPG2_24H:C04 Gene Set
Genes
48 genes differentially expressed following the CRCGN009_HEPG2_24H:C04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
7.9287
|
|
MYLK
|
myosin light chain kinase
|
5.0429
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.98127
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
4.91756
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.45008
|
|
ABHD4
|
abhydrolase domain containing 4
|
4.27695
|
|
MICALL1
|
MICAL-like 1
|
3.99116
|
|
STAP2
|
signal transducing adaptor family member 2
|
3.82249
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.63881
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.50199
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.48311
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.41691
|
|
FCHO1
|
FCH domain only 1
|
3.24568
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.11736
|
|
CRTAP
|
cartilage associated protein
|
2.9474
|
|
SFTPB
|
surfactant protein B
|
2.41813
|
|
PRR15L
|
proline rich 15-like
|
2.41177
|
|
KIF20A
|
kinesin family member 20A
|
2.40897
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.29921
|
|
ATP13A1
|
ATPase type 13A1
|
2.25214
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
2.21781
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
2.17688
|
|
GPATCH8
|
G patch domain containing 8
|
2.17109
|
|
ZNF589
|
zinc finger protein 589
|
2.16027
|
|
VGLL4
|
vestigial-like family member 4
|
2.14239
|
|
BMP4
|
bone morphogenetic protein 4
|
2.08804
|
|
SH3GL1
|
SH3-domain GRB2-like 1
|
2.0808
|
|
ETV4
|
ets variant 4
|
2.02204
|
|
AMACR
|
alpha-methylacyl-CoA racemase
|
2.01986
|
|
ITGAV
|
integrin, alpha V
|
2.01197
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-9.81068
|
|
LDHD
|
lactate dehydrogenase D
|
-8.74312
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-8.72565
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-6.07798
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-5.98369
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.25936
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.0
|
|
CDC20
|
cell division cycle 20
|
-4.96565
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-4.41165
|
|
ZNF586
|
zinc finger protein 586
|
-3.14606
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.98357
|
|
CCNB2
|
cyclin B2
|
-2.63566
|
|
TOPBP1
|
topoisomerase (DNA) II binding protein 1
|
-2.51045
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.47026
|
|
HMG20B
|
high mobility group 20B
|
-2.34744
|
|
NDUFA10
|
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
|
-2.12471
|
|
GSDMB
|
gasdermin B
|
-2.05138
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
-2.01574
|
