| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tetrakis(hydroxymethyl)phos-phonium chloride 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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74 genes differentially expressed following the CRCGN009_HEPG2_24H:C06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 | 6.69665 |
| STIMATE | STIM activating enhancer | 6.63649 |
| HOXA10 | homeobox A10 | 6.14752 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.91631 |
| PLS1 | plastin 1 | 5.1892 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 5.18425 |
| CBR1 | carbonyl reductase 1 | 5.02933 |
| CHN1 | chimerin 1 | 4.96398 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 4.74554 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.6421 |
| HDGFL3 | HDGF like 3 | 4.13276 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 3.90053 |
| RXYLT1 | ribitol xylosyltransferase 1 | 3.78421 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.6157 |
| H2BC12 | H2B clustered histone 12 | 3.61499 |
| MYLK | myosin light chain kinase | 3.58324 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.42663 |
| UBQLN2 | ubiquilin 2 | 3.40406 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.14096 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.94476 |
| GPATCH8 | G patch domain containing 8 | 2.85944 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.74617 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.73006 |
| HOXA10-HOXA9 | HOXA10-HOXA9 readthrough | 2.70885 |
| LARS2 | leucyl-tRNA synthetase 2, mitochondrial | 2.69406 |
| EVL | Enah/Vasp-like | 2.57612 |
| HOXA11 | homeobox A11 | 2.55797 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 2.51299 |
| FASTKD1 | FAST kinase domains 1 | 2.34997 |
| MTERF3 | mitochondrial transcription termination factor 3 | 2.31537 |
| ZNF589 | zinc finger protein 589 | 2.30353 |
| USPL1 | ubiquitin specific peptidase like 1 | 2.30024 |
| PRR15L | proline rich 15-like | 2.24352 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 2.18834 |
| ZBTB25 | zinc finger and BTB domain containing 25 | 2.15416 |
| ZBTB32 | zinc finger and BTB domain containing 32 | 2.09355 |
| C1S | complement component 1, s subcomponent | 2.09268 |
| LAG3 | lymphocyte-activation gene 3 | 2.07616 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 2.02577 |
| TMEM41B | transmembrane protein 41B | 2.02026 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | 2.00117 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -8.28642 |
| TLR4 | toll-like receptor 4 | -8.06314 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -6.35332 |
| COG7 | component of oligomeric golgi complex 7 | -5.76054 |
| ADI1 | acireductone dioxygenase 1 | -5.50236 |
| ACOT9 | acyl-CoA thioesterase 9 | -5.105 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.07643 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -4.17142 |
| CCNB2 | cyclin B2 | -4.1464 |
| SNX11 | sorting nexin 11 | -3.86532 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.80821 |
| CAB39 | calcium binding protein 39 | -3.50149 |
| CCNB1 | cyclin B1 | -3.40665 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -3.39717 |
| CSK | c-src tyrosine kinase | -3.10419 |
| RNF167 | ring finger protein 167 | -2.61166 |
| KLF4 | Kruppel-like factor 4 (gut) | -2.55328 |
| MTA1 | metastasis associated 1 | -2.44975 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.3799 |
| VASP | vasodilator-stimulated phosphoprotein | -2.25774 |
| TASL | TLR adaptor interacting with endolysosomal SLC15A4 | -2.23336 |
| SPAG4 | sperm associated antigen 4 | -2.17557 |
| PRDX4 | peroxiredoxin 4 | -2.15328 |
| FLCN | folliculin | -2.15066 |
| TES | testin LIM domain protein | -2.13765 |
| NPIPA6 | nuclear pore complex interacting protein family, member A6 | -2.11841 |
| EGF | epidermal growth factor | -2.09942 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -2.09659 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 | -2.09276 |
| SP2 | Sp2 transcription factor | -2.08516 |
| TSC1 | tuberous sclerosis 1 | -2.07392 |
| MILR1 | mast cell immunoglobulin-like receptor 1 | -2.07128 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | -2.0019 |
