CRCGN009_HEPG2_24H:C09 Gene Set
Genes
48 genes differentially expressed following the CRCGN009_HEPG2_24H:C09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
10.0
|
|
RPL39L
|
ribosomal protein L39-like
|
5.22904
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
5.04221
|
|
CHMP6
|
charged multivesicular body protein 6
|
5.03377
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.67321
|
|
HOXA10
|
homeobox A10
|
4.4035
|
|
LCN2
|
lipocalin 2
|
3.97762
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.90363
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.8625
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
3.53992
|
|
AXIN1
|
axin 1
|
3.36953
|
|
MAP7
|
microtubule-associated protein 7
|
3.23102
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.1412
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.99631
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.85858
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.82533
|
|
SYBU
|
syntabulin (syntaxin-interacting)
|
2.49184
|
|
SIRT3
|
sirtuin 3
|
2.48087
|
|
EPHB2
|
EPH receptor B2
|
2.47316
|
|
CCNF
|
cyclin F
|
2.3005
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.24386
|
|
CNTNAP1
|
contactin associated protein 1
|
2.18409
|
|
HOXA10-HOXA9
|
HOXA10-HOXA9 readthrough
|
2.15576
|
|
GATA3
|
GATA binding protein 3
|
2.15298
|
|
MRPL46
|
mitochondrial ribosomal protein L46
|
2.14957
|
|
CACNA1D
|
calcium channel, voltage-dependent, L type, alpha 1D subunit
|
2.08259
|
|
JADE2
|
jade family PHD finger 2
|
2.06838
|
|
HOXA11
|
homeobox A11
|
2.06073
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.38332
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-5.16365
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-4.93942
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.9007
|
|
CD58
|
CD58 molecule
|
-4.6745
|
|
LDHD
|
lactate dehydrogenase D
|
-4.66677
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.6076
|
|
DSG2
|
desmoglein 2
|
-4.17744
|
|
NUP93
|
nucleoporin 93kDa
|
-4.03085
|
|
ZNF586
|
zinc finger protein 586
|
-3.95581
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.88924
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.60274
|
|
SNX11
|
sorting nexin 11
|
-3.09055
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.4284
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
-2.40812
|
|
TLR4
|
toll-like receptor 4
|
-2.37947
|
|
CMTR1
|
cap methyltransferase 1
|
-2.21115
|
|
CCNB1
|
cyclin B1
|
-2.16808
|
|
NECTIN4
|
nectin cell adhesion molecule 4
|
-2.09546
|
|
TBC1D2
|
TBC1 domain family, member 2
|
-2.05805
|
