CRCGN009_HEPG2_24H:C13 Gene Set
Genes
45 genes differentially expressed following the CRCGN009_HEPG2_24H:C13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
7.54111
|
|
CYCS
|
cytochrome c, somatic
|
4.80512
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.29001
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.28306
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.9312
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.72949
|
|
PMM2
|
phosphomannomutase 2
|
3.2229
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.15609
|
|
MAP7
|
microtubule-associated protein 7
|
3.09016
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.04114
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
2.98177
|
|
FZD7
|
frizzled class receptor 7
|
2.90769
|
|
RAB21
|
RAB21, member RAS oncogene family
|
2.59171
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.53273
|
|
STK10
|
serine/threonine kinase 10
|
2.52141
|
|
TSPAN6
|
tetraspanin 6
|
2.51608
|
|
ZNF589
|
zinc finger protein 589
|
2.34457
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.32584
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.26437
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.20819
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.14983
|
|
EVL
|
Enah/Vasp-like
|
2.13098
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.07006
|
|
PIP4K2B
|
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
|
2.00842
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-5.78631
|
|
GNAS
|
GNAS complex locus
|
-5.62821
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-5.10707
|
|
THAP11
|
THAP domain containing 11
|
-3.89046
|
|
CD320
|
CD320 molecule
|
-3.72929
|
|
HMG20B
|
high mobility group 20B
|
-3.63668
|
|
BLCAP
|
bladder cancer associated protein
|
-3.61695
|
|
CCNB2
|
cyclin B2
|
-3.41946
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.41582
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.40546
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.30422
|
|
LDHD
|
lactate dehydrogenase D
|
-3.25943
|
|
GLOD4
|
glyoxalase domain containing 4
|
-3.06535
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.74863
|
|
ZNF274
|
zinc finger protein 274
|
-2.45562
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.44125
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.35939
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.19507
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.11123
|
|
CCDC92
|
coiled-coil domain containing 92
|
-2.06822
|
|
NOX5
|
NADPH oxidase, EF-hand calcium binding domain 5
|
-2.05953
|
