| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | thioacetamide 20.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
77 genes differentially expressed following the CRCGN009_HEPG2_24H:C14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 10.0 |
| MAP7 | microtubule-associated protein 7 | 7.85589 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 5.97958 |
| PMM2 | phosphomannomutase 2 | 5.413 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 5.31419 |
| CHN1 | chimerin 1 | 5.31398 |
| LPAR2 | lysophosphatidic acid receptor 2 | 5.1599 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.96382 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.94906 |
| LCN2 | lipocalin 2 | 4.57926 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 4.43252 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.35948 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.21034 |
| HOXA10 | homeobox A10 | 4.14156 |
| STIMATE | STIM activating enhancer | 3.59862 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.54241 |
| SOCS2 | suppressor of cytokine signaling 2 | 3.35094 |
| MEST | mesoderm specific transcript | 3.31137 |
| EVL | Enah/Vasp-like | 3.11451 |
| NENF | neudesin neurotrophic factor | 3.01842 |
| MICALL1 | MICAL-like 1 | 2.94493 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.78312 |
| MCM3 | minichromosome maintenance complex component 3 | 2.77326 |
| EGF | epidermal growth factor | 2.6838 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 2.6821 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.67442 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.47629 |
| PRR15L | proline rich 15-like | 2.45517 |
| JADE2 | jade family PHD finger 2 | 2.44724 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.44231 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.36786 |
| HOXA10-HOXA9 | HOXA10-HOXA9 readthrough | 2.31675 |
| SNX7 | sorting nexin 7 | 2.28356 |
| TUFM | Tu translation elongation factor, mitochondrial | 2.17602 |
| FPGS | folylpolyglutamate synthase | 2.14451 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.08797 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.0486 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.00938 |
| NOSIP | nitric oxide synthase interacting protein | 2.001 |
| EMX2 | empty spiracles homeobox 2 | 2.00023 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -9.16686 |
| VAT1 | vesicle amine transport 1 | -5.17696 |
| UGDH | UDP-glucose 6-dehydrogenase | -4.98963 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -4.88899 |
| COG2 | component of oligomeric golgi complex 2 | -4.63136 |
| LDHD | lactate dehydrogenase D | -4.4584 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.38653 |
| PCNA | proliferating cell nuclear antigen | -4.36401 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -4.11628 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.05755 |
| ADI1 | acireductone dioxygenase 1 | -4.01894 |
| TLR4 | toll-like receptor 4 | -3.99893 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.83804 |
| CD58 | CD58 molecule | -3.57924 |
| YME1L1 | YME1-like 1 ATPase | -3.4769 |
| GNAS | GNAS complex locus | -3.17389 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.1382 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -3.13172 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.89428 |
| TRAPPC6A | trafficking protein particle complex 6A | -2.85767 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.76455 |
| CCNB2 | cyclin B2 | -2.68272 |
| SULT2A1 | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | -2.63154 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -2.48588 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.43801 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.27261 |
| ORM2 | orosomucoid 2 | -2.25739 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.21742 |
| SNX11 | sorting nexin 11 | -2.17535 |
| SMC6 | structural maintenance of chromosomes 6 | -2.16199 |
| RCL1 | RNA terminal phosphate cyclase-like 1 | -2.1389 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -2.10711 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.07353 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 | -2.05913 |
| CSDC2 | cold shock domain containing C2, RNA binding | -2.05103 |
| JADE1 | jade family PHD finger 1 | -2.01265 |
| SCCPDH | saccharopine dehydrogenase (putative) | -2.00006 |
