CRCGN009_HEPG2_24H:C15 Gene Set
Genes
50 genes differentially expressed following the CRCGN009_HEPG2_24H:C15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STIMATE
|
STIM activating enhancer
|
7.36223
|
|
LCN2
|
lipocalin 2
|
5.64871
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
5.58239
|
|
MAP7
|
microtubule-associated protein 7
|
4.65995
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.44368
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.95618
|
|
E2F2
|
E2F transcription factor 2
|
3.61097
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.56443
|
|
GPATCH8
|
G patch domain containing 8
|
3.42944
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.35819
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.34308
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.9987
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.90657
|
|
INTS3
|
integrator complex subunit 3
|
2.8984
|
|
VGLL4
|
vestigial-like family member 4
|
2.65577
|
|
MSRA
|
methionine sulfoxide reductase A
|
2.63639
|
|
CBR3
|
carbonyl reductase 3
|
2.59209
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.50537
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.39571
|
|
RRAGA
|
Ras-related GTP binding A
|
2.36869
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.36704
|
|
EPN2
|
epsin 2
|
2.33785
|
|
EVL
|
Enah/Vasp-like
|
2.28311
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.26656
|
|
UBQLN2
|
ubiquilin 2
|
2.19093
|
|
TSPAN6
|
tetraspanin 6
|
2.17998
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.10279
|
|
TBP
|
TATA box binding protein
|
2.08369
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.03567
|
|
SLC15A2
|
solute carrier family 15 (oligopeptide transporter), member 2
|
2.02427
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-7.31671
|
|
ADI1
|
acireductone dioxygenase 1
|
-5.81117
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-5.75821
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-3.76408
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-3.29908
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.04431
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.89794
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.75788
|
|
CSK
|
c-src tyrosine kinase
|
-2.67834
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.66083
|
|
LDHD
|
lactate dehydrogenase D
|
-2.55398
|
|
EXT1
|
exostosin glycosyltransferase 1
|
-2.51068
|
|
RPIA
|
ribose 5-phosphate isomerase A
|
-2.39787
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.3481
|
|
KREMEN2
|
kringle containing transmembrane protein 2
|
-2.29006
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.16689
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.06695
|
|
ZNF586
|
zinc finger protein 586
|
-2.04759
|
|
PHF1
|
PHD finger protein 1
|
-2.04286
|
|
LRP6
|
low density lipoprotein receptor-related protein 6
|
-2.00619
|
