CRCGN009_HEPG2_24H:C17 Gene Set
Genes
47 genes differentially expressed following the CRCGN009_HEPG2_24H:C17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
7.11248
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
6.29643
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
5.43911
|
|
MAP7
|
microtubule-associated protein 7
|
4.47409
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.30167
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.25541
|
|
RPL39L
|
ribosomal protein L39-like
|
4.17705
|
|
HOXA10
|
homeobox A10
|
3.78351
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.73255
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.69784
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.61481
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
3.58105
|
|
EPHB2
|
EPH receptor B2
|
3.21583
|
|
UBQLN2
|
ubiquilin 2
|
3.17224
|
|
E2F2
|
E2F transcription factor 2
|
3.12695
|
|
MYBL2
|
v-myb avian myeloblastosis viral oncogene homolog-like 2
|
2.95724
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.88787
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.53899
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.51365
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.47136
|
|
CCNF
|
cyclin F
|
2.41833
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.22387
|
|
MKNK1
|
MAP kinase interacting serine/threonine kinase 1
|
2.20124
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.16796
|
|
CDC45
|
cell division cycle 45
|
2.11776
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.10124
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.0949
|
|
JADE2
|
jade family PHD finger 2
|
2.05549
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.69531
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.79137
|
|
SPAG4
|
sperm associated antigen 4
|
-3.79091
|
|
CD320
|
CD320 molecule
|
-3.76602
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.70872
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.4755
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.12775
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.83017
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.67372
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.47642
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.47306
|
|
VAT1
|
vesicle amine transport 1
|
-2.46364
|
|
CCNB1
|
cyclin B1
|
-2.36232
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.3586
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.20497
|
|
NVL
|
nuclear VCP-like
|
-2.16877
|
|
SCAND1
|
SCAN domain containing 1
|
-2.05833
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.05752
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-2.02275
|
