CRCGN009_HEPG2_24H:C18 Gene Set
Genes
36 genes differentially expressed following the CRCGN009_HEPG2_24H:C18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
8.03739
|
|
PFKL
|
phosphofructokinase, liver
|
6.54272
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.35091
|
|
MYLK
|
myosin light chain kinase
|
6.2253
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.85354
|
|
MAP7
|
microtubule-associated protein 7
|
5.71765
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.85845
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.50393
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.42228
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
4.17817
|
|
GATD3
|
glutamine amidotransferase class 1 domain containing 3
|
3.89992
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
3.14808
|
|
TEX10
|
testis expressed 10
|
2.51597
|
|
PWP2
|
PWP2 periodic tryptophan protein homolog (yeast)
|
2.40464
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.38283
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.31354
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.30085
|
|
MRPL39
|
mitochondrial ribosomal protein L39
|
2.20479
|
|
LOC102724594
|
splicing factor U2AF 35 kDa subunit
|
2.20189
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.1226
|
|
EPHA3
|
EPH receptor A3
|
2.09924
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
EGF
|
epidermal growth factor
|
-4.17226
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.00493
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.88385
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.73473
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.70753
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.6358
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.19821
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.89036
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.83676
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.62017
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.36149
|
|
SLC6A14
|
solute carrier family 6 (amino acid transporter), member 14
|
-2.20529
|
|
RPS5
|
ribosomal protein S5
|
-2.19343
|
|
ASAH1
|
N-acylsphingosine amidohydrolase (acid ceramidase) 1
|
-2.1266
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.04284
|
