CRCGN009_HEPG2_24H:C24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description mitoxantrone 0.63 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

1412 genes differentially expressed following the CRCGN009_HEPG2_24H:C24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
BLCAP bladder cancer associated protein 10.0
RPP38 ribonuclease P/MRP 38kDa subunit 10.0
LCN2 lipocalin 2 10.0
INPP1 inositol polyphosphate-1-phosphatase 10.0
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 10.0
CCDC92 coiled-coil domain containing 92 9.66407
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 9.47521
TIMP2 TIMP metallopeptidase inhibitor 2 9.44911
LRP10 low density lipoprotein receptor-related protein 10 9.16629
ABHD4 abhydrolase domain containing 4 8.68339
DDB2 damage-specific DNA binding protein 2, 48kDa 8.57078
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 8.04192
IGFBP3 insulin-like growth factor binding protein 3 7.80852
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 7.79476
MVP major vault protein 7.75454
MICALL1 MICAL-like 1 7.66074
UBQLN2 ubiquilin 2 7.36148
H2BC12 H2B clustered histone 12 6.90791
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 6.79737
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 6.60753
TERF2IP telomeric repeat binding factor 2, interacting protein 6.2513
GPC1 glypican 1 6.23448
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 6.23439
EGR1 early growth response 1 6.22803
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 5.98438
INTS3 integrator complex subunit 3 5.97278
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 5.95839
LOXL1 lysyl oxidase-like 1 5.94248
DUSP14 dual specificity phosphatase 14 5.92729
PRKCQ protein kinase C, theta 5.85623
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 5.79329
MAN2B1 mannosidase, alpha, class 2B, member 1 5.67031
H2BC21 H2B clustered histone 21 5.58877
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 5.50886
IER3 immediate early response 3 5.50765
TNIP1 TNFAIP3 interacting protein 1 5.4914
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 5.48077
MCOLN1 mucolipin 1 5.46239
TIGAR TP53 induced glycolysis regulatory phosphatase 5.3347
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 5.32619
CTSL cathepsin L 5.31503
MINDY1 MINDY lysine 48 deubiquitinase 1 5.18327
BECN1 beclin 1, autophagy related 5.16307
CNPY3 canopy FGF signaling regulator 3 5.12472
CTTN cortactin 5.08631
KIFBP kinesin family binding protein 5.06886
NIT1 nitrilase 1 5.0582
SLC75A1 solute carrier family 75 member 1 5.0564
TRIB1 tribbles pseudokinase 1 5.04983
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 5.00032
FOSL1 FOS-like antigen 1 4.9388
PRKCD protein kinase C, delta 4.91894
ASCC3 activating signal cointegrator 1 complex subunit 3 4.88899
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 4.84994
SMAD3 SMAD family member 3 4.72886
BACE2 beta-site APP-cleaving enzyme 2 4.72443
PHLDA3 pleckstrin homology-like domain, family A, member 3 4.71636
GALE UDP-galactose-4-epimerase 4.71205
RBM15B RNA binding motif protein 15B 4.65653
TUBB6 tubulin, beta 6 class V 4.6335
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 4.52574
DUSP6 dual specificity phosphatase 6 4.52016
XPC xeroderma pigmentosum, complementation group C 4.49665
STX4 syntaxin 4 4.46157
SKIC2 SKI2 subunit of superkiller complex 4.43615
PNKP polynucleotide kinase 3'-phosphatase 4.43055
PLK3 polo-like kinase 3 4.39886
SCAND1 SCAN domain containing 1 4.34745
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 4.32815
FOXO4 forkhead box O4 4.32202
YPEL5 yippee-like 5 (Drosophila) 4.32086
FOXJ3 forkhead box J3 4.32024
IL4R interleukin 4 receptor 4.29587
ADGRG1 adhesion G protein-coupled receptor G1 4.27001
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 4.22731
KLHL21 kelch-like family member 21 4.19964
FRS2 fibroblast growth factor receptor substrate 2 4.17456
GRN granulin 4.12841
MAD2L1BP MAD2L1 binding protein 4.1012
MAP7D1 MAP7 domain containing 1 4.09239
MTCH1 mitochondrial carrier 1 4.08563
ZNF79 zinc finger protein 79 4.08327
RALB v-ral simian leukemia viral oncogene homolog B 4.04893
UBE2A ubiquitin-conjugating enzyme E2A 4.03889
PLA2G15 phospholipase A2, group XV 4.01886
ZNF557 zinc finger protein 557 4.01229
PTPN6 protein tyrosine phosphatase, non-receptor type 6 4.00306
DHRS7 dehydrogenase/reductase (SDR family) member 7 3.96994
MYLK myosin light chain kinase 3.89374
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 3.87646
H2AC6 H2A clustered histone 6 3.81183
THSD1 thrombospondin, type I, domain containing 1 3.80903
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 3.80003
TOMM34 translocase of outer mitochondrial membrane 34 3.7988
TREM2 triggering receptor expressed on myeloid cells 2 3.78413
S100A13 S100 calcium binding protein A13 3.7805
FBXL12 F-box and leucine-rich repeat protein 12 3.77725
LSR lipolysis stimulated lipoprotein receptor 3.76238
CDK9 cyclin-dependent kinase 9 3.7518
IFNAR1 interferon (alpha, beta and omega) receptor 1 3.74408
ATG9A autophagy related 9A 3.7404
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 3.73643
BAD BCL2-associated agonist of cell death 3.7284
ACOT9 acyl-CoA thioesterase 9 3.69711
PHF1 PHD finger protein 1 3.68398
ERCC5 excision repair cross-complementation group 5 3.67092
OPTN optineurin 3.64154
SNX7 sorting nexin 7 3.62579
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 3.62374
ZMAT3 zinc finger, matrin-type 3 3.61939
CAB39 calcium binding protein 39 3.61349
RNF25 ring finger protein 25 3.58954
GIPC1 GIPC PDZ domain containing family, member 1 3.57227
CDKL3 cyclin-dependent kinase-like 3 3.56634
DDR1 discoidin domain receptor tyrosine kinase 1 3.55884
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 3.55633
TNFAIP8L2-SCNM1 TNFAIP8L2-SCNM1 readthrough 3.54296
ISCU iron-sulfur cluster assembly enzyme 3.53925
MBD1 methyl-CpG binding domain protein 1 3.53073
ITFG1 integrin alpha FG-GAP repeat containing 1 3.5204
FASTKD5 FAST kinase domains 5 3.51984
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 3.50868
TOR1A torsin family 1, member A (torsin A) 3.50511
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.49475
ZNF394 zinc finger protein 394 3.4901
GPN2 GPN-loop GTPase 2 3.47823
TMEM59 transmembrane protein 59 3.45631
GSDME gasdermin E 3.45535
HCFC2 host cell factor C2 3.45273
HSPB1 heat shock 27kDa protein 1 3.44835
CAVIN1 caveolae associated protein 1 3.42492
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 3.42257
COG7 component of oligomeric golgi complex 7 3.41914
SNIP1 Smad nuclear interacting protein 1 3.41527
NCOA6 nuclear receptor coactivator 6 3.40322
ATG2A autophagy related 2A 3.4018
CLK3 CDC-like kinase 3 3.40142
IDUA iduronidase, alpha-L- 3.40102
TWF2 twinfilin actin binding protein 2 3.39717
YY1AP1 YY1 associated protein 1 3.3928
NOTCH1 notch 1 3.37032
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.35946
TEX10 testis expressed 10 3.34795
VEGFC vascular endothelial growth factor C 3.34736
CSNK1G3 casein kinase 1, gamma 3 3.3424
EMC3 ER membrane protein complex subunit 3 3.33325
SERINC3 serine incorporator 3 3.33243
CASC3 cancer susceptibility candidate 3 3.33135
MOCS3 molybdenum cofactor synthesis 3 3.32917
FAM50A family with sequence similarity 50, member A 3.3209
MON1B MON1 secretory trafficking family member B 3.31013
SRC SRC proto-oncogene, non-receptor tyrosine kinase 3.30805
CDK5RAP1 CDK5 regulatory subunit associated protein 1 3.30554
KDM5A lysine (K)-specific demethylase 5A 3.29167
H1-2 H1.2 linker histone, cluster member 3.28609
UFM1 ubiquitin-fold modifier 1 3.27782
KDM3A lysine (K)-specific demethylase 3A 3.26931
LPAR2 lysophosphatidic acid receptor 2 3.2683
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.23597
GPR87 G protein-coupled receptor 87 3.23241
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 3.22413
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 3.19788
SAA2 serum amyloid A2 3.19094
YJU2B YJU2 splicing factor homolog B 3.17596
SQSTM1 sequestosome 1 3.17328
TOE1 target of EGR1, member 1 (nuclear) 3.17113
SETD1A SET domain containing 1A 3.16977
TRIM8 tripartite motif containing 8 3.16654
COL7A1 collagen, type VII, alpha 1 3.15775
MIDEAS mitotic deacetylase associated SANT domain protein 3.14753
ABITRAM actin binding transcription modulator 3.14071
MLF2 myeloid leukemia factor 2 3.13629
ZC3H12A zinc finger CCCH-type containing 12A 3.13304
RNF220 ring finger protein 220 3.13227
CBR3 carbonyl reductase 3 3.12323
COL4A6 collagen, type IV, alpha 6 3.11946
HSPB6 heat shock protein, alpha-crystallin-related, B6 3.11934
RAB5IF RAB5 interacting factor 3.11852
HSPA1A heat shock 70kDa protein 1A 3.11432
MMP24-AS1-EDEM2 MMP24-AS1-EDEM2 readthrough 3.10733
GADD45A growth arrest and DNA-damage-inducible, alpha 3.10094
MAPK13 mitogen-activated protein kinase 13 3.09338
EPAS1 endothelial PAS domain protein 1 3.08682
GABARAPL1 GABA(A) receptor-associated protein like 1 3.08148
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 3.0796
TGFB1I1 transforming growth factor beta 1 induced transcript 1 3.065
SIN3B SIN3 transcription regulator family member B 3.05606
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 3.05023
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 3.04907
TRAPPC6A trafficking protein particle complex 6A 3.04898
TRAPPC14 trafficking protein particle complex subunit 14 3.04118
CTSD cathepsin D 3.04068
ZBTB48 zinc finger and BTB domain containing 48 3.03665
ITCH itchy E3 ubiquitin protein ligase 3.02923
GLRX glutaredoxin (thioltransferase) 3.02819
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 3.02772
MAPKBP1 mitogen-activated protein kinase binding protein 1 3.02303
MOSPD1 motile sperm domain containing 1 3.02186
PINK1 PTEN induced putative kinase 1 3.02053
SERINC1 serine incorporator 1 3.01562
LAP3 leucine aminopeptidase 3 3.01119
C1QL1 complement component 1, q subcomponent-like 1 3.00981
KHDC4 KH domain containing 4, pre-mRNA splicing factor 3.00634
SPATA20 spermatogenesis associated 20 2.99906
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 2.99671
NSUN3 NOP2/Sun domain family, member 3 2.9955
ERCC3 excision repair cross-complementation group 3 2.99019
ITGAV integrin, alpha V 2.98069
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 2.97616
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 2.97546
STN1 STN1 subunit of CST complex 2.97289
EGFR epidermal growth factor receptor 2.97168
RBKS ribokinase 2.9668
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) 2.96481
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) 2.95368
RB1CC1 RB1-inducible coiled-coil 1 2.94534
ZNF629 zinc finger protein 629 2.94346
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 2.93918
YIPF3 Yip1 domain family, member 3 2.92883
SYF2 SYF2 pre-mRNA-splicing factor 2.91988
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.9142
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.91325
RNF4 ring finger protein 4 2.90916
MEIS1 Meis homeobox 1 2.9063
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 2.90376
TRIM38 tripartite motif containing 38 2.90303
BBC3 BCL2 binding component 3 2.90257
DOLK dolichol kinase 2.89942
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 2.89847
METTL25B methyltransferase like 25B 2.89755
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 2.89603
ASB8 ankyrin repeat and SOCS box containing 8 2.86494
TMEM187 transmembrane protein 187 2.86299
ELL2 elongation factor, RNA polymerase II, 2 2.86225
FAM32A family with sequence similarity 32, member A 2.85953
STOM stomatin 2.85697
ASTE1 asteroid homolog 1 (Drosophila) 2.84981
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.84774
PGAP6 post-GPI attachment to proteins 6 2.84738
TUBG2 tubulin, gamma 2 2.84648
SNAP29 synaptosomal-associated protein, 29kDa 2.84469
BAX BCL2-associated X protein 2.83752
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.83234
METTL22 methyltransferase like 22 2.83144
ROGDI rogdi homolog (Drosophila) 2.81984
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 2.81219
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 2.81115
STAT1 signal transducer and activator of transcription 1, 91kDa 2.81034
MOAP1 modulator of apoptosis 1 2.80684
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 2.80524
ELP3 elongator acetyltransferase complex subunit 3 2.80383
HSF2BP heat shock transcription factor 2 binding protein 2.8031
MNT MAX network transcriptional repressor 2.80217
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.80173
VPS9D1 VPS9 domain containing 1 2.80094
H2AC19 H2A clustered histone 19 2.79959
FDXR ferredoxin reductase 2.79883
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.79362
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.78773
SYNPO synaptopodin 2.78391
RSF1 remodeling and spacing factor 1 2.78115
NCF2 neutrophil cytosolic factor 2 2.78097
DNASE1L1 deoxyribonuclease I-like 1 2.77696
DOK7 docking protein 7 2.77527
CCDC57 coiled-coil domain containing 57 2.77481
WFS1 Wolfram syndrome 1 (wolframin) 2.7736
MAP3K14 mitogen-activated protein kinase kinase kinase 14 2.76685
GBA1 glucosylceramidase beta 1 2.7655
EIF6 eukaryotic translation initiation factor 6 2.76512
LGMN legumain 2.76403
CHIT1 chitinase 1 (chitotriosidase) 2.75534
TRIP12 thyroid hormone receptor interactor 12 2.75181
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 2.75047
CFLAR CASP8 and FADD-like apoptosis regulator 2.74882
APH1B APH1B gamma secretase subunit 2.7421
LAMC2 laminin, gamma 2 2.74048
LAMA5 laminin, alpha 5 2.74038
FADD Fas (TNFRSF6)-associated via death domain 2.73688
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.72563
FXR2 fragile X mental retardation, autosomal homolog 2 2.71925
CSRNP2 cysteine-serine-rich nuclear protein 2 2.71891
LOC124900275 extensin-like 2.71563
BMP1 bone morphogenetic protein 1 2.7068
MBD5 methyl-CpG binding domain protein 5 2.70389
SCPEP1 serine carboxypeptidase 1 2.69989
F8A2 coagulation factor VIII-associated 2 2.69438
CNPPD1 cyclin Pas1/PHO80 domain containing 1 2.69324
MMP9 matrix metallopeptidase 9 2.68893
WBP4 WW domain binding protein 4 2.68607
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 2.68149
KLHL36 kelch-like family member 36 2.6803
CPM carboxypeptidase M 2.67947
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.67377
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.67265
AKAP8 A kinase (PRKA) anchor protein 8 2.67157
UBE2L6 ubiquitin-conjugating enzyme E2L 6 2.67148
ELF4 E74-like factor 4 (ets domain transcription factor) 2.67143
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.67064
TEAD3 TEA domain family member 3 2.66982
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.66818
UBN1 ubinuclein 1 2.66612
RRAGC Ras-related GTP binding C 2.66407
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 2.66143
SQOR sulfide quinone oxidoreductase 2.65952
CAMLG calcium modulating ligand 2.65414
GAK cyclin G associated kinase 2.65386
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 2.65286
ZBTB43 zinc finger and BTB domain containing 43 2.65235
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 2.65091
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.65059
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like 2.65014
PTPRR protein tyrosine phosphatase, receptor type, R 2.64062
COL4A5 collagen, type IV, alpha 5 2.63899
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.63718
KHDC1L KH homology domain containing 1-like 2.63457
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 2.63031
MSMB microseminoprotein, beta- 2.62807
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 2.62646
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 2.62645
GHITM growth hormone inducible transmembrane protein 2.62619
ANXA8L1 annexin A8-like 1 2.62274
TRIAP1 TP53 regulated inhibitor of apoptosis 1 2.6221
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.61863
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 2.61141
EHD2 EH-domain containing 2 2.60988
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 2.60948
DIPK1A divergent protein kinase domain 1A 2.60879
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 2.60821
TRIM32 tripartite motif containing 32 2.60782
FRMD4B FERM domain containing 4B 2.60702
NPTXR neuronal pentraxin receptor 2.60585
GTPBP8 GTP-binding protein 8 (putative) 2.6058
THAP10 THAP domain containing 10 2.59745
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.59717
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 2.59248
UBR2 ubiquitin protein ligase E3 component n-recognin 2 2.59137
PPIE peptidylprolyl isomerase E (cyclophilin E) 2.58745
TICAM1 toll-like receptor adaptor molecule 1 2.58002
FERRY3 FERRY endosomal RAB5 effector complex subunit 3 2.57592
ZNHIT2 zinc finger, HIT-type containing 2 2.57388
GDI1 GDP dissociation inhibitor 1 2.57378
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.56791
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 2.563
CIC capicua transcriptional repressor 2.56247
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 2.56067
BTG2 BTG family, member 2 2.56018
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 2.55766
CGRRF1 cell growth regulator with ring finger domain 1 2.54677
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 2.54564
DUSP3 dual specificity phosphatase 3 2.53707
OSGIN1 oxidative stress induced growth inhibitor 1 2.53648
COL17A1 collagen, type XVII, alpha 1 2.53526
ZBED5 zinc finger, BED-type containing 5 2.53141
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 2.53094
LAMB3 laminin, beta 3 2.52301
EFHC1 EF-hand domain (C-terminal) containing 1 2.52203
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 2.52127
ARMCX4 armadillo repeat containing, X-linked 4 2.5202
SOX15 SRY (sex determining region Y)-box 15 2.51969
TEX14 testis expressed 14 2.51942
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 2.51923
SFXN3 sideroflexin 3 2.51831
RETREG2 reticulophagy regulator family member 2 2.51766
TBC1D2 TBC1 domain family, member 2 2.51682
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) 2.51624
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 2.51598
CYTH2 cytohesin 2 2.51456
QRICH1 glutamine-rich 1 2.51264
ADRB2 adrenoceptor beta 2, surface 2.50971
ALAS1 5'-aminolevulinate synthase 1 2.50927
PEX26 peroxisomal biogenesis factor 26 2.50675
PDCD10 programmed cell death 10 2.50639
PPARD peroxisome proliferator-activated receptor delta 2.5
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 2.49932
UBE2H ubiquitin-conjugating enzyme E2H 2.49527
NPDC1 neural proliferation, differentiation and control, 1 2.49499
ASB7 ankyrin repeat and SOCS box containing 7 2.49188
PARP6 poly (ADP-ribose) polymerase family, member 6 2.48995
PAGE4 P antigen family, member 4 (prostate associated) 2.48829
MAP3K11 mitogen-activated protein kinase kinase kinase 11 2.48654
WDR26 WD repeat domain 26 2.48619
TMEM185B transmembrane protein 185B 2.48294
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.48218
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 2.48111
CCSER2 coiled-coil serine-rich protein 2 2.47778
GCLC glutamate-cysteine ligase, catalytic subunit 2.47734
EIF1B eukaryotic translation initiation factor 1B 2.477
AVPI1 arginine vasopressin-induced 1 2.47695
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 2.47659
SPTAN1 spectrin, alpha, non-erythrocytic 1 2.47596
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.47465
ZNF768 zinc finger protein 768 2.47379
PNRC1 proline-rich nuclear receptor coactivator 1 2.47183
ADGRF1 adhesion G protein-coupled receptor F1 2.46989
JAK1 Janus kinase 1 2.46266
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.45926
DYNLRB1 dynein, light chain, roadblock-type 1 2.45861
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 2.4585
CNPY4 canopy FGF signaling regulator 4 2.45672
EEF1B2 eukaryotic translation elongation factor 1 beta 2 2.45594
MRPL33 mitochondrial ribosomal protein L33 2.45539
E2F2 E2F transcription factor 2 2.45415
TSPAN3 tetraspanin 3 2.45393
RIC8A RIC8 guanine nucleotide exchange factor A 2.45267
DOK4 docking protein 4 2.44999
CLEC16A C-type lectin domain family 16, member A 2.44994
CLBA1 clathrin binding box of aftiphilin containing 1 2.44888
EAPP E2F-associated phosphoprotein 2.44755
AOPEP aminopeptidase O (putative) 2.44617
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 2.44392
TP53I3 tumor protein p53 inducible protein 3 2.4428
LYRM2 LYR motif containing 2 2.44118
PROCR protein C receptor, endothelial 2.44047
HOXD11 homeobox D11 2.43794
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.43791
MEAF6 MYST/Esa1-associated factor 6 2.43618
MICALL2 MICAL-like 2 2.43533
OFD1 oral-facial-digital syndrome 1 2.43032
FPGS folylpolyglutamate synthase 2.42574
EMC7 ER membrane protein complex subunit 7 2.42454
CHD3 chromodomain helicase DNA binding protein 3 2.42367
KIAA0232 KIAA0232 2.42269
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.41906
SUGCT succinyl-CoA:glutarate-CoA transferase 2.41763
CDK20 cyclin-dependent kinase 20 2.40926
MAN2A1 mannosidase, alpha, class 2A, member 1 2.40751
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 2.40451
DKKL1 dickkopf-like 1 2.40138
RC3H2 ring finger and CCCH-type domains 2 2.40116
GALNS galactosamine (N-acetyl)-6-sulfatase 2.40059
BPNT2 3'(2'), 5'-bisphosphate nucleotidase 2 2.39607
CIRSR corepressor of RBPJ and splicing regulator 2.39452
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.39432
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.39395
SETBP1 SET binding protein 1 2.39347
POMT1 protein-O-mannosyltransferase 1 2.39198
RFX5 regulatory factor X, 5 (influences HLA class II expression) 2.39182
PEX19 peroxisomal biogenesis factor 19 2.39063
KIFC3 kinesin family member C3 2.39059
APOE apolipoprotein E 2.38916
MYL5 myosin, light chain 5, regulatory 2.38606
NINJ1 ninjurin 1 2.38481
BAG6 BCL2-associated athanogene 6 2.38396
PAOX polyamine oxidase (exo-N4-amino) 2.38248
RUSC2 RUN and SH3 domain containing 2 2.38071
SAGE1 sarcoma antigen 1 2.37825
SIRT7 sirtuin 7 2.37787
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.37558
IRF9 interferon regulatory factor 9 2.37196
TCP11L1 t-complex 11, testis-specific-like 1 2.37099
GAS6 growth arrest-specific 6 2.36906
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.36798
GABARAPL2 GABA(A) receptor-associated protein-like 2 2.36364
NBR1 neighbor of BRCA1 gene 1 2.36309
ADAR adenosine deaminase, RNA-specific 2.36145
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 2.36128
ROM1 retinal outer segment membrane protein 1 2.36077
HPSE heparanase 2.36054
ATMIN ATM interactor 2.35491
ICAM5 intercellular adhesion molecule 5, telencephalin 2.3529
MEGF8 multiple EGF-like-domains 8 2.35267
RTF2 replication termination factor 2 2.35216
TM9SF4 transmembrane 9 superfamily protein member 4 2.35022
CPLX3 complexin 3 2.34528
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 2.34242
SERTAD3 SERTA domain containing 3 2.34102
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 2.33366
TGFB3 transforming growth factor, beta 3 2.33363
EPHA2 EPH receptor A2 2.33338
ZNF148 zinc finger protein 148 2.33291
CORO7-PAM16 CORO7-PAM16 readthrough 2.33169
FSTL3 follistatin-like 3 (secreted glycoprotein) 2.33012
ADNP activity-dependent neuroprotector homeobox 2.32931
RGCC regulator of cell cycle 2.32914
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 2.32584
DPF2 D4, zinc and double PHD fingers family 2 2.32571
RING1 ring finger protein 1 2.32486
ZYX zyxin 2.32351
ZER1 zyg-11 related, cell cycle regulator 2.32326
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 2.31909
TMUB2 transmembrane and ubiquitin-like domain containing 2 2.31907
ATF3 activating transcription factor 3 2.31776
SMIM7 small integral membrane protein 7 2.31358
CSNK1G1 casein kinase 1, gamma 1 2.31278
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 2.31182
TRIM13 tripartite motif containing 13 2.30829
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 2.30639
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 2.30439
RASAL2 RAS protein activator like 2 2.30365
SPATA7 spermatogenesis associated 7 2.30329
ARID5B AT rich interactive domain 5B (MRF1-like) 2.30163
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.30104
HOXA1 homeobox A1 2.29486
BABAM2 BRISC and BRCA1 A complex member 2 2.29438
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 2.29373
BTG3 BTG family, member 3 2.29321
ULK1 unc-51 like autophagy activating kinase 1 2.29313
TM9SF2 transmembrane 9 superfamily member 2 2.29287
POLR1D polymerase (RNA) I polypeptide D, 16kDa 2.29158
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.29083
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 2.29029
TRIM11 tripartite motif containing 11 2.28942
CALCOCO1 calcium binding and coiled-coil domain 1 2.28774
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2.28719
MEIS2 Meis homeobox 2 2.28664
CREBBP CREB binding protein 2.28628
DGKA diacylglycerol kinase, alpha 80kDa 2.28556
SZT2 seizure threshold 2 homolog (mouse) 2.2853
PLEC plectin 2.2846
ODR4 odr-4 GPCR localization factor homolog 2.28311
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.28294
ZNF33B zinc finger protein 33B 2.28012
FUCA1 fucosidase, alpha-L- 1, tissue 2.27716
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.27699
TEX11 testis expressed 11 2.27529
MED9 mediator complex subunit 9 2.27449
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit 2.27209
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 2.26961
SPEG SPEG complex locus 2.26892
TRIM68 tripartite motif containing 68 2.26733
DCAF16 DDB1 and CUL4 associated factor 16 2.2673
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.26353
HOXD10 homeobox D10 2.26303
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 2.26254
KCTD17 potassium channel tetramerization domain containing 17 2.26141
SCHIP1 schwannomin interacting protein 1 2.25675
EED embryonic ectoderm development 2.25492
SLC25A44 solute carrier family 25, member 44 2.25476
ASXL1 additional sex combs like transcriptional regulator 1 2.25449
TWIST1 twist family bHLH transcription factor 1 2.25272
UTP11 UTP11 small subunit processome component 2.25008
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 2.24923
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.24874
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2.24787
LITAF lipopolysaccharide-induced TNF factor 2.24625
JUN jun proto-oncogene 2.24622
SLC67A1 solute carrier family 67 member 1 2.24621
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 2.24588
KLF7 Kruppel-like factor 7 (ubiquitous) 2.24544
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 2.24517
CLSTN3 calsyntenin 3 2.2447
WDR73 WD repeat domain 73 2.2411
ALOX15B arachidonate 15-lipoxygenase, type B 2.238
TMSB10 thymosin beta 10 2.23621
ACYP2 acylphosphatase 2, muscle type 2.23563
CARD10 caspase recruitment domain family, member 10 2.23434
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.23377
CCNA1 cyclin A1 2.23359
TACR2 tachykinin receptor 2 2.23288
WASHC5 WASH complex subunit 5 2.2324
FBXW4 F-box and WD repeat domain containing 4 2.23232
RNF115 ring finger protein 115 2.23226
FLRT2 fibronectin leucine rich transmembrane protein 2 2.23204
CD9 CD9 molecule 2.23006
RPL21 ribosomal protein L21 2.22917
ZMPSTE24 zinc metallopeptidase STE24 2.22903
MED15 mediator complex subunit 15 2.22834
CLSTN2 calsyntenin 2 2.22622
LARP6 La ribonucleoprotein domain family, member 6 2.22465
IGF1R insulin-like growth factor 1 receptor 2.22416
RGPD1 RANBP2-like and GRIP domain containing 1 2.22401
MAN2C1 mannosidase, alpha, class 2C, member 1 2.2239
H2BC14 H2B clustered histone 14 2.22358
GAPVD1 GTPase activating protein and VPS9 domains 1 2.22194
COQ8A coenzyme Q8A 2.22163
PDLIM7 PDZ and LIM domain 7 (enigma) 2.21826
ZNF23 zinc finger protein 23 2.21733
TFE3 transcription factor binding to IGHM enhancer 3 2.21731
ORAI3 ORAI calcium release-activated calcium modulator 3 2.21699
SREBF1 sterol regulatory element binding transcription factor 1 2.2144
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 2.21195
SCRN1 secernin 1 2.21133
KRT17 keratin 17, type I 2.21127
IRS1 insulin receptor substrate 1 2.21102
PTPRF protein tyrosine phosphatase, receptor type, F 2.20992
SOCS2 suppressor of cytokine signaling 2 2.20726
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 2.20597
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 2.20478
MMP24OS MMP24 opposite strand 2.20433
DCTN6 dynactin 6 2.2036
CST3 cystatin C 2.20241
TRIM22 tripartite motif containing 22 2.20102
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 2.20013
MXI1 MAX interactor 1, dimerization protein 2.19977
MCUR1 mitochondrial calcium uniporter regulator 1 2.19696
TERF2 telomeric repeat binding factor 2 2.19648
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 2.19533
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 2.19137
NGF nerve growth factor (beta polypeptide) 2.19035
ZNF646 zinc finger protein 646 2.18991
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 2.18949
OXLD1 oxidoreductase-like domain containing 1 2.18434
HLA-E major histocompatibility complex, class I, E 2.18286
ZNF580 zinc finger protein 580 2.18166
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 2.18082
FLRT3 fibronectin leucine rich transmembrane protein 3 2.18004
MTMR1 myotubularin related protein 1 2.17742
BAK1 BCL2-antagonist/killer 1 2.17597
RHOG ras homolog family member G 2.17307
ABI2 abl-interactor 2 2.17282
PLEKHO1 pleckstrin homology domain containing, family O member 1 2.17033
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.17027
EFNB1 ephrin-B1 2.16849
THTPA thiamine triphosphatase 2.16774
MSTO1 misato 1, mitochondrial distribution and morphology regulator 2.16531
FBRS fibrosin 2.16473
RNF113A ring finger protein 113A 2.16407
PLPP1 phospholipid phosphatase 1 2.1613
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 2.15969
GULP1 GULP, engulfment adaptor PTB domain containing 1 2.15758
COQ9 coenzyme Q9 2.15378
PER3 period circadian clock 3 2.15371
TMEM131 transmembrane protein 131 2.1504
BBS4 Bardet-Biedl syndrome 4 2.14664
H2AC7 H2A clustered histone 7 2.14204
NIPAL3 NIPA-like domain containing 3 2.14029
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 2.13852
TMEM184C transmembrane protein 184C 2.13802
RPS19 ribosomal protein S19 2.13762
BAG3 BCL2-associated athanogene 3 2.13726
PHF21A PHD finger protein 21A 2.13395
PPME1 protein phosphatase methylesterase 1 2.13137
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 2.13087
PIGV phosphatidylinositol glycan anchor biosynthesis, class V 2.12977
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2.12301
WDR1 WD repeat domain 1 2.12208
AMZ2 archaelysin family metallopeptidase 2 2.12114
NME8 NME/NM23 family member 8 2.12069
GIGYF2 GRB10 interacting GYF protein 2 2.11886
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.11877
WNT10B wingless-type MMTV integration site family, member 10B 2.11791
MEA1 male-enhanced antigen 1 2.11604
H2BC4 H2B clustered histone 4 2.11588
RPL12 ribosomal protein L12 2.11559
RABGGTA Rab geranylgeranyltransferase, alpha subunit 2.11512
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 2.11338
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 2.1122
NOP2 NOP2 nucleolar protein 2.11181
CRIPT cysteine-rich PDZ-binding protein 2.10858
MRPS15 mitochondrial ribosomal protein S15 2.10459
BRSK2 BR serine/threonine kinase 2 2.10449
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2.10227
CFB complement factor B 2.09859
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa 2.09626
GPBP1L1 GC-rich promoter binding protein 1-like 1 2.09601
IL1B interleukin 1, beta 2.09456
WDR44 WD repeat domain 44 2.09431
TSG101 tumor susceptibility 101 2.09334
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 2.09096
ATG4A autophagy related 4A, cysteine peptidase 2.09031
ZNF12 zinc finger protein 12 2.08981
NBEA neurobeachin 2.08968
PORCN porcupine homolog (Drosophila) 2.08962
FBXL8 F-box and leucine-rich repeat protein 8 2.08884
RNF103-CHMP3 RNF103-CHMP3 readthrough 2.08379
BASP1 brain abundant, membrane attached signal protein 1 2.082
WNT5B wingless-type MMTV integration site family, member 5B 2.08126
MAIP1 matrix AAA peptidase interacting protein 1 2.08085
AEN apoptosis enhancing nuclease 2.08043
SUN2 Sad1 and UNC84 domain containing 2 2.0798
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 2.07926
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 2.07913
PIAS3 protein inhibitor of activated STAT, 3 2.07897
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 2.07854
CIAO2B cytosolic iron-sulfur assembly component 2B 2.07434
DMRT1 doublesex and mab-3 related transcription factor 1 2.07432
CCNJL cyclin J-like 2.07381
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 2.07251
ARSA arylsulfatase A 2.07144
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 2.07075
SCRN3 secernin 3 2.07041
HLA-DMA major histocompatibility complex, class II, DM alpha 2.07011
MEF2D myocyte enhancer factor 2D 2.06988
ATOSB atos homolog B 2.06894
DDA1 DET1 and DDB1 associated 1 2.06732
ZFYVE26 zinc finger, FYVE domain containing 26 2.06552
CKB creatine kinase, brain 2.06513
H2AC25 H2A clustered histone 25 2.06429
PTPRM protein tyrosine phosphatase, receptor type, M 2.06023
SETD3 SET domain containing 3 2.05773
NEFH neurofilament, heavy polypeptide 2.05768
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 2.05763
HEXIM1 hexamethylene bis-acetamide inducible 1 2.05674
NYNRIN NYN domain and retroviral integrase containing 2.05591
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 2.05499
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 2.05473
OVCA2 ovarian tumor suppressor candidate 2 2.05438
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 2.05419
MYO5A myosin VA (heavy chain 12, myoxin) 2.0511
IER2 immediate early response 2 2.05109
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 2.05071
OSER1 oxidative stress responsive serine-rich 1 2.04904
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 2.04741
MTMR14 myotubularin related protein 14 2.04496
ZMIZ1 zinc finger, MIZ-type containing 1 2.04467
HPS6 Hermansky-Pudlak syndrome 6 2.04449
CAVIN3 caveolae associated protein 3 2.04407
USP27X ubiquitin specific peptidase 27, X-linked 2.04034
BFSP1 beaded filament structural protein 1, filensin 2.04001
COL9A2 collagen, type IX, alpha 2 2.03934
HOXA4 homeobox A4 2.03711
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 2.03587
SLC44A4 solute carrier family 44, member 4 2.03585
YME1L1 YME1-like 1 ATPase 2.03566
GTPBP2 GTP binding protein 2 2.03533
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 2.03453
RNF103 ring finger protein 103 2.03453
H2BC5 H2B clustered histone 5 2.03417
RPRD2 regulation of nuclear pre-mRNA domain containing 2 2.03406
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 2.03402
DOHH deoxyhypusine hydroxylase/monooxygenase 2.03347
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.03144
WDR83OS WD repeat domain 83 opposite strand 2.02972
ELMO2 engulfment and cell motility 2 2.02864
UBFD1 ubiquitin family domain containing 1 2.02785
MAU2 MAU2 sister chromatid cohesion factor 2.02681
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 2.02301
EGR4 early growth response 4 2.02137
PRRC2C proline-rich coiled-coil 2C 2.02053
DHRS3 dehydrogenase/reductase (SDR family) member 3 2.02028
NFS1 NFS1 cysteine desulfurase 2.01987
ATG12 autophagy related 12 2.01978
PTCD2 pentatricopeptide repeat domain 2 2.01977
ISG20 interferon stimulated exonuclease gene 20kDa 2.01914
MLYCD malonyl-CoA decarboxylase 2.0186
TMEM127 transmembrane protein 127 2.0167
MSLN mesothelin 2.01663
ZMYM2 zinc finger, MYM-type 2 2.01628
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 2.01295
FAM246A family with sequence similarity 246 member A 2.01263
HCCS holocytochrome c synthase 2.01214
ERCC6 excision repair cross-complementation group 6 2.01182
HUNK hormonally up-regulated Neu-associated kinase 2.00509
RPS12 ribosomal protein S12 2.00395
CDH22 cadherin 22, type 2 2.00335
EDN1 endothelin 1 2.00217
VAMP7 vesicle-associated membrane protein 7 2.00136
LRRC47 leucine rich repeat containing 47 2.00074

decreased expression

Symbol Name Standardized Value
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -10.0
PLK1 polo-like kinase 1 -10.0
RPIA ribose 5-phosphate isomerase A -10.0
MELK maternal embryonic leucine zipper kinase -10.0
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -10.0
CDC20 cell division cycle 20 -10.0
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -10.0
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -10.0
PYCR1 pyrroline-5-carboxylate reductase 1 -10.0
LBR lamin B receptor -9.98585
RFC2 replication factor C (activator 1) 2, 40kDa -9.46372
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -9.42851
TCTN1 tectonic family member 1 -9.08586
CCNA2 cyclin A2 -8.75878
UBE2C ubiquitin-conjugating enzyme E2C -8.70366
STMN1 stathmin 1 -8.59092
MYC v-myc avian myelocytomatosis viral oncogene homolog -8.43917
PSRC1 proline/serine-rich coiled-coil 1 -8.36455
ETFB electron-transfer-flavoprotein, beta polypeptide -8.28281
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -8.27982
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -8.14218
HACD3 3-hydroxyacyl-CoA dehydratase 3 -8.06863
CCNB1 cyclin B1 -8.03512
NT5DC2 5'-nucleotidase domain containing 2 -7.88562
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -7.77184
ZW10 zw10 kinetochore protein -7.69024
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -7.65857
AURKB aurora kinase B -7.6308
BIRC5 baculoviral IAP repeat containing 5 -7.39715
TOP2A topoisomerase (DNA) II alpha 170kDa -7.2379
NUP85 nucleoporin 85kDa -7.16139
TCERG1 transcription elongation regulator 1 -7.12795
CHEK1 checkpoint kinase 1 -7.108
CDK1 cyclin-dependent kinase 1 -7.0721
FGFR4 fibroblast growth factor receptor 4 -6.92029
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -6.90139
BLMH bleomycin hydrolase -6.87364
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -6.57495
PCCB propionyl CoA carboxylase, beta polypeptide -6.51709
PCNA proliferating cell nuclear antigen -6.23021
CCNB2 cyclin B2 -6.17347
PGM1 phosphoglucomutase 1 -6.02888
ENOPH1 enolase-phosphatase 1 -5.96764
HAT1 histone acetyltransferase 1 -5.8163
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -5.80493
KIF11 kinesin family member 11 -5.7115
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -5.66261
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -5.63545
CDK4 cyclin-dependent kinase 4 -5.55618
GINS2 GINS complex subunit 2 (Psf2 homolog) -5.45368
KIF15 kinesin family member 15 -5.42531
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -5.4168
SPC25 SPC25, NDC80 kinetochore complex component -5.39295
TLR4 toll-like receptor 4 -5.38304
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -5.38173
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -5.17084
PHGDH phosphoglycerate dehydrogenase -5.15958
KIF4A kinesin family member 4A -5.10204
CENPA centromere protein A -5.08787
HMGA2 high mobility group AT-hook 2 -5.08217
RACGAP1 Rac GTPase activating protein 1 -5.06451
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -5.06347
TMEM109 transmembrane protein 109 -5.06113
CDC6 cell division cycle 6 -5.04877
KIF14 kinesin family member 14 -5.0481
AARS1 alanyl-tRNA synthetase 1 -4.87766
TIMELESS timeless circadian clock -4.86681
CENPE centromere protein E, 312kDa -4.85815
FABP5 fatty acid binding protein 5 (psoriasis-associated) -4.85201
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -4.84476
ZNF586 zinc finger protein 586 -4.83665
MSH6 mutS homolog 6 -4.81328
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -4.81324
TMEM97 transmembrane protein 97 -4.80304
TPX2 TPX2, microtubule-associated -4.76539
CHEK2 checkpoint kinase 2 -4.74637
HMMR hyaluronan-mediated motility receptor (RHAMM) -4.69673
NCAPG2 non-SMC condensin II complex, subunit G2 -4.69264
CD320 CD320 molecule -4.68618
DCK deoxycytidine kinase -4.54785
POLR1A polymerase (RNA) I polypeptide A, 194kDa -4.5421
POLK polymerase (DNA directed) kappa -4.523
ASF1B anti-silencing function 1B histone chaperone -4.51331
CDT1 chromatin licensing and DNA replication factor 1 -4.51136
HMGB2 high mobility group box 2 -4.50296
MYL9 myosin, light chain 9, regulatory -4.48108
TEDC2 tubulin epsilon and delta complex 2 -4.46037
B4GAT1 beta-1,4-glucuronyltransferase 1 -4.44451
TK1 thymidine kinase 1, soluble -4.41698
LOC124907782 dual specificity protein phosphatase 22 -4.41627
ALDOC aldolase C, fructose-bisphosphate -4.38755
CDC25B cell division cycle 25B -4.38088
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -4.36301
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -4.35586
FOXM1 forkhead box M1 -4.34255
AURKA aurora kinase A -4.32359
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -4.29861
KIF18B kinesin family member 18B -4.28399
MIS18A MIS18 kinetochore protein A -4.26706
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.25771
GET1 guided entry of tail-anchored proteins factor 1 -4.24833
DSCC1 DNA replication and sister chromatid cohesion 1 -4.22636
WEE1 WEE1 G2 checkpoint kinase -4.21663
FBXO5 F-box protein 5 -4.21301
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -4.18855
CDCA3 cell division cycle associated 3 -4.16822
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -4.15705
CHAF1A chromatin assembly factor 1, subunit A (p150) -4.15472
SPAG5 sperm associated antigen 5 -4.15238
OIP5 Opa interacting protein 5 -4.15237
IFRD2 interferon-related developmental regulator 2 -4.13625
BZW2 basic leucine zipper and W2 domains 2 -4.12496
CHAF1B chromatin assembly factor 1, subunit B (p60) -4.10785
TROAP trophinin associated protein -4.10774
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -4.10268
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -4.10213
UNG uracil-DNA glycosylase -4.08555
LMNB1 lamin B1 -4.07842
PBK PDZ binding kinase -4.0523
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -4.00641
DAZAP1 DAZ associated protein 1 -3.99034
HADH hydroxyacyl-CoA dehydrogenase -3.97986
USP1 ubiquitin specific peptidase 1 -3.97735
UBE2S ubiquitin-conjugating enzyme E2S -3.97313
ORC6 origin recognition complex, subunit 6 -3.9269
PROS1 protein S (alpha) -3.89799
DHFR dihydrofolate reductase -3.88214
POLR1G RNA polymerase I subunit G -3.86372
MRPL12 mitochondrial ribosomal protein L12 -3.85012
PTGES3 prostaglandin E synthase 3 (cytosolic) -3.84252
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.83355
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -3.8317
ADI1 acireductone dioxygenase 1 -3.82539
GFUS GDP-L-fucose synthase -3.82454
WDR18 WD repeat domain 18 -3.81955
GTSE1 G-2 and S-phase expressed 1 -3.81213
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.8104
KIF18A kinesin family member 18A -3.8064
PARPBP PARP1 binding protein -3.80097
SCCPDH saccharopine dehydrogenase (putative) -3.79838
UGDH UDP-glucose 6-dehydrogenase -3.78852
TMPO thymopoietin -3.78356
SKA1 spindle and kinetochore associated complex subunit 1 -3.78341
RFC3 replication factor C (activator 1) 3, 38kDa -3.77834
ISOC1 isochorismatase domain containing 1 -3.75277
MCM5 minichromosome maintenance complex component 5 -3.73664
PYGL phosphorylase, glycogen, liver -3.7355
BORA bora, aurora kinase A activator -3.72708
POLE polymerase (DNA directed), epsilon, catalytic subunit -3.71505
TTK TTK protein kinase -3.71141
MCM10 minichromosome maintenance complex component 10 -3.71079
PECR peroxisomal trans-2-enoyl-CoA reductase -3.69176
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa -3.67682
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.66654
GAR1 GAR1 ribonucleoprotein -3.66514
CDCA8 cell division cycle associated 8 -3.66112
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta -3.64649
CLIC4 chloride intracellular channel 4 -3.64014
TLCD3A TLC domain containing 3A -3.63023
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.62843
CENPM centromere protein M -3.61291
NUP93 nucleoporin 93kDa -3.60419
CDC25A cell division cycle 25A -3.59648
ZWINT ZW10 interacting kinetochore protein -3.58826
FEN1 flap structure-specific endonuclease 1 -3.58548
GINS1 GINS complex subunit 1 (Psf1 homolog) -3.58237
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -3.57384
ERCC6L excision repair cross-complementation group 6-like -3.56509
PLK4 polo-like kinase 4 -3.5561
GCSH glycine cleavage system protein H (aminomethyl carrier) -3.55478
DONSON downstream neighbor of SON -3.54054
CDKN3 cyclin-dependent kinase inhibitor 3 -3.52664
RFC5 replication factor C (activator 1) 5, 36.5kDa -3.52645
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -3.52006
ECT2 epithelial cell transforming 2 -3.5163
TFDP1 transcription factor Dp-1 -3.50734
PUS1 pseudouridylate synthase 1 -3.5059
NUP37 nucleoporin 37kDa -3.47889
MCMBP minichromosome maintenance complex binding protein -3.47313
TRIP13 thyroid hormone receptor interactor 13 -3.45128
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -3.45081
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -3.44701
MRPS2 mitochondrial ribosomal protein S2 -3.43781
SOAT2 sterol O-acyltransferase 2 -3.43287
RBM14-RBM4 RBM14-RBM4 readthrough -3.42174
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -3.39989
TIPIN TIMELESS interacting protein -3.39584
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.3946
NEK2 NIMA-related kinase 2 -3.38862
SMC4 structural maintenance of chromosomes 4 -3.38853
TRMT5 tRNA methyltransferase 5 -3.38334
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.37447
DTYMK deoxythymidylate kinase (thymidylate kinase) -3.3644
NRIP1 nuclear receptor interacting protein 1 -3.35897
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -3.35064
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -3.35003
MKI67 marker of proliferation Ki-67 -3.34911
ACAA1 acetyl-CoA acyltransferase 1 -3.33509
ELOVL6 ELOVL fatty acid elongase 6 -3.32402
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.31118
NCAPH non-SMC condensin I complex, subunit H -3.30191
VDAC1 voltage-dependent anion channel 1 -3.28755
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -3.28411
GCAT glycine C-acetyltransferase -3.27959
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -3.27511
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -3.26957
TRIB3 tribbles pseudokinase 3 -3.26649
MCM4 minichromosome maintenance complex component 4 -3.26544
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -3.26534
EXO1 exonuclease 1 -3.26105
PDIA5 protein disulfide isomerase family A, member 5 -3.25236
KIF23 kinesin family member 23 -3.24091
PRC1 protein regulator of cytokinesis 1 -3.23876
SNRPA small nuclear ribonucleoprotein polypeptide A -3.23299
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -3.22932
USP6NL USP6 N-terminal like -3.22922
MCM6 minichromosome maintenance complex component 6 -3.22405
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -3.217
DEPDC1 DEP domain containing 1 -3.21663
CDK2 cyclin-dependent kinase 2 -3.18929
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -3.18898
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -3.1863
NUP133 nucleoporin 133kDa -3.17952
RNF130 ring finger protein 130 -3.17649
HNRNPM heterogeneous nuclear ribonucleoprotein M -3.17179
SHCBP1 SHC SH2-domain binding protein 1 -3.17177
HMG20B high mobility group 20B -3.15773
PGRMC1 progesterone receptor membrane component 1 -3.15732
DNA2 DNA replication helicase/nuclease 2 -3.1527
DUT deoxyuridine triphosphatase -3.1449
HELLS helicase, lymphoid-specific -3.11991
AEBP1 AE binding protein 1 -3.11015
TBC1D10C TBC1 domain family, member 10C -3.10231
FIRRM FIGNL1 interacting regulator of recombination and mitosis -3.10119
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -3.09791
U2SURP U2 snRNP-associated SURP domain containing -3.07828
VRK1 vaccinia related kinase 1 -3.07253
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.06927
AXIN1 axin 1 -3.06868
PSAT1 phosphoserine aminotransferase 1 -3.05918
FTCD formimidoyltransferase cyclodeaminase -3.05787
THOP1 thimet oligopeptidase 1 -3.05709
OAT ornithine aminotransferase -3.04676
GPT glutamic-pyruvate transaminase (alanine aminotransferase) -3.04222
ADISSP adipose secreted signaling protein -3.0203
HJURP Holliday junction recognition protein -3.0171
MCUB mitochondrial calcium uniporter dominant negative subunit beta -3.01314
DCPS decapping enzyme, scavenger -2.99358
TRAIP TRAF interacting protein -2.9932
VGLL4 vestigial-like family member 4 -2.99263
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.99103
VASH2 vasohibin 2 -2.98866
CEP55 centrosomal protein 55kDa -2.97164
NENF neudesin neurotrophic factor -2.96655
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -2.96179
RFC4 replication factor C (activator 1) 4, 37kDa -2.95783
SRSF3 serine/arginine-rich splicing factor 3 -2.95643
NUP210 nucleoporin 210kDa -2.95217
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.95074
PIMREG PICALM interacting mitotic regulator -2.94299
ICAM3 intercellular adhesion molecule 3 -2.94098
MRPL19 mitochondrial ribosomal protein L19 -2.9339
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -2.92941
KIF22 kinesin family member 22 -2.9264
BFSP2 beaded filament structural protein 2, phakinin -2.92529
MAT1A methionine adenosyltransferase I, alpha -2.92274
TM9SF3 transmembrane 9 superfamily member 3 -2.92009
EMC9 ER membrane protein complex subunit 9 -2.91494
CRIPTO3 cripto, EGF-CFC family member 3 -2.91312
COBL cordon-bleu WH2 repeat protein -2.91038
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -2.90999
XPOT exportin, tRNA -2.90905
ATAD2 ATPase family, AAA domain containing 2 -2.9051
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) -2.90419
MCM7 minichromosome maintenance complex component 7 -2.89942
TMEM123 transmembrane protein 123 -2.89856
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -2.89722
BTBD2 BTB (POZ) domain containing 2 -2.89452
SIPA1L1 signal-induced proliferation-associated 1 like 1 -2.8895
CASP7 caspase 7, apoptosis-related cysteine peptidase -2.88493
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -2.8845
CKS2 CDC28 protein kinase regulatory subunit 2 -2.86398
RCN3 reticulocalbin 3, EF-hand calcium binding domain -2.8607
NFYB nuclear transcription factor Y, beta -2.85953
VCAN versican -2.84644
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.84456
SPDL1 spindle apparatus coiled-coil protein 1 -2.8444
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -2.83521
S100B S100 calcium binding protein B -2.83436
FPR2 formyl peptide receptor 2 -2.8259
MBL2 mannose-binding lectin (protein C) 2, soluble -2.82045
ICMT isoprenylcysteine carboxyl methyltransferase -2.81965
UXT ubiquitously-expressed, prefoldin-like chaperone -2.81823
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.80868
ATL2 atlastin GTPase 2 -2.80865
PXMP2 peroxisomal membrane protein 2, 22kDa -2.80266
SNX10 sorting nexin 10 -2.79973
DCN decorin -2.79816
ARHGAP11A Rho GTPase activating protein 11A -2.79048
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -2.7903
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.78794
NDC1 NDC1 transmembrane nucleoporin -2.78784
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -2.78041
DCTD dCMP deaminase -2.77929
LAGE3 L antigen family, member 3 -2.77756
RRM2 ribonucleotide reductase M2 -2.77721
EGF epidermal growth factor -2.77479
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.76044
MARCO macrophage receptor with collagenous structure -2.76029
GGCT gamma-glutamylcyclotransferase -2.76024
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -2.7567
HMGN2 high mobility group nucleosomal binding domain 2 -2.75548
WDHD1 WD repeat and HMG-box DNA binding protein 1 -2.75363
SRSF2 serine/arginine-rich splicing factor 2 -2.7514
CENPU centromere protein U -2.73898
BIRC2 baculoviral IAP repeat containing 2 -2.72823
RNASE4 ribonuclease, RNase A family, 4 -2.72793
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.72379
INCENP inner centromere protein antigens 135/155kDa -2.72299
WRAP53 WD repeat containing, antisense to TP53 -2.71992
EIF4E eukaryotic translation initiation factor 4E -2.71812
ANAPC5 anaphase promoting complex subunit 5 -2.71474
LARS1 leucyl-tRNA synthetase 1 -2.71329
KIF20B kinesin family member 20B -2.70788
ZNF107 zinc finger protein 107 -2.7075
ENO1 enolase 1, (alpha) -2.70132
FBL fibrillarin -2.70102
NPC1 Niemann-Pick disease, type C1 -2.7002
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -2.69839
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.6924
CLDN3 claudin 3 -2.69194
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.68628
SAP30 Sin3A-associated protein, 30kDa -2.68604
ANKRD28 ankyrin repeat domain 28 -2.68498
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -2.68233
ASGR1 asialoglycoprotein receptor 1 -2.68117
GLOD4 glyoxalase domain containing 4 -2.67826
MPST mercaptopyruvate sulfurtransferase -2.67307
UBXN8 UBX domain protein 8 -2.66533
SNRPF small nuclear ribonucleoprotein polypeptide F -2.66215
TACC3 transforming, acidic coiled-coil containing protein 3 -2.65906
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -2.65697
FABP1 fatty acid binding protein 1, liver -2.65681
SMCO4 single-pass membrane protein with coiled-coil domains 4 -2.65196
PTTG1 pituitary tumor-transforming 1 -2.64938
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -2.64623
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -2.64501
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -2.64382
TTLL12 tubulin tyrosine ligase-like family member 12 -2.63809
GSTM5 glutathione S-transferase mu 5 -2.63615
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -2.63526
DHRS4 dehydrogenase/reductase (SDR family) member 4 -2.63075
BRCA1 breast cancer 1, early onset -2.62779
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.62753
ARID3A AT rich interactive domain 3A (BRIGHT-like) -2.62619
DBF4 DBF4 zinc finger -2.62533
ADH6 alcohol dehydrogenase 6 (class V) -2.62242
TXLNG taxilin gamma -2.61904
PLG plasminogen -2.61903
ALG3 ALG3, alpha-1,3- mannosyltransferase -2.60609
CERK ceramide kinase -2.59736
RAD51AP1 RAD51 associated protein 1 -2.5949
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -2.58838
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -2.58613
PAH phenylalanine hydroxylase -2.57848
MAGOHB mago-nashi homolog B (Drosophila) -2.567
SLC35F2 solute carrier family 35, member F2 -2.56249
ICAM2 intercellular adhesion molecule 2 -2.56159
DCTPP1 dCTP pyrophosphatase 1 -2.55571
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -2.55025
SPDEF SAM pointed domain containing ETS transcription factor -2.54036
ZNF83 zinc finger protein 83 -2.53845
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.53749
GPHN gephyrin -2.53638
PFAS phosphoribosylformylglycinamidine synthase -2.53307
PRPF31 pre-mRNA processing factor 31 -2.52908
MLANA melan-A -2.5287
SCARB1 scavenger receptor class B, member 1 -2.52547
PDK3 pyruvate dehydrogenase kinase, isozyme 3 -2.52116
FANCA Fanconi anemia, complementation group A -2.52084
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 -2.51982
FANCG Fanconi anemia, complementation group G -2.51436
LCK LCK proto-oncogene, Src family tyrosine kinase -2.51263
PPID peptidylprolyl isomerase D -2.5113
GLYAT glycine-N-acyltransferase -2.50983
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -2.50445
PCDHGA3 protocadherin gamma subfamily A, 3 -2.50078
TCTN2 tectonic family member 2 -2.50026
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.49766
BHMT betaine--homocysteine S-methyltransferase -2.48841
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.48837
MSH2 mutS homolog 2 -2.48671
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.48323
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -2.47835
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -2.47442
RUVBL2 RuvB-like AAA ATPase 2 -2.47399
HSPE1 heat shock 10kDa protein 1 -2.4715
CENPF centromere protein F, 350/400kDa -2.47112
RBBP8 retinoblastoma binding protein 8 -2.46888
MDN1 MDN1, midasin homolog (yeast) -2.46737
STIL SCL/TAL1 interrupting locus -2.46219
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -2.46085
NHP2 NHP2 ribonucleoprotein -2.45673
GAMT guanidinoacetate N-methyltransferase -2.45407
MIS18BP1 MIS18 binding protein 1 -2.45266
AGMAT agmatine ureohydrolase (agmatinase) -2.45191
CHL1 cell adhesion molecule L1-like -2.44498
PARP1 poly (ADP-ribose) polymerase 1 -2.44477
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -2.44444
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -2.43901
HEATR1 HEAT repeat containing 1 -2.43878
DCPH1 damage control phosphatase 1 -2.43762
H2AZ1 H2A.Z variant histone 1 -2.43745
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.43511
LYZ lysozyme -2.43486
VDAC3 voltage-dependent anion channel 3 -2.43313
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -2.43295
PHF10 PHD finger protein 10 -2.4324
GSTCD glutathione S-transferase, C-terminal domain containing -2.43133
MPHOSPH9 M-phase phosphoprotein 9 -2.43121
AKR1D1 aldo-keto reductase family 1, member D1 -2.4303
FKBP5 FK506 binding protein 5 -2.42942
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.42837
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -2.42763
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -2.4213
MRPL3 mitochondrial ribosomal protein L3 -2.41982
TRAK2 trafficking protein, kinesin binding 2 -2.41728
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 -2.41477
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -2.41411
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -2.41238
HAUS6 HAUS augmin-like complex, subunit 6 -2.41169
AZGP1 alpha-2-glycoprotein 1, zinc-binding -2.4067
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.40397
KLK12 kallikrein-related peptidase 12 -2.40278
POLD2 polymerase (DNA directed), delta 2, accessory subunit -2.39229
GALK1 galactokinase 1 -2.38763
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.38733
PHKB phosphorylase kinase, beta -2.38295
HNRNPF heterogeneous nuclear ribonucleoprotein F -2.38201
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -2.38162
CHMP6 charged multivesicular body protein 6 -2.38061
PIPOX pipecolic acid oxidase -2.38028
PEBP1 phosphatidylethanolamine binding protein 1 -2.37888
EIF4H eukaryotic translation initiation factor 4H -2.37572
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.37333
GABPA GA binding protein transcription factor, alpha subunit 60kDa -2.37306
LRRC61 leucine rich repeat containing 61 -2.36576
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.36496
RUVBL1 RuvB-like AAA ATPase 1 -2.3647
GLB1L2 galactosidase, beta 1-like 2 -2.36465
IRX5 iroquois homeobox 5 -2.36457
GNG3 guanine nucleotide binding protein (G protein), gamma 3 -2.36372
WDR43 WD repeat domain 43 -2.36325
ARHGAP19 Rho GTPase activating protein 19 -2.36188
GMDS GDP-mannose 4,6-dehydratase -2.36152
PRODH2 proline dehydrogenase (oxidase) 2 -2.36025
CCT7 chaperonin containing TCP1, subunit 7 (eta) -2.35803
VRK2 vaccinia related kinase 2 -2.35284
CDC7 cell division cycle 7 -2.35121
H2AX H2A.X variant histone -2.35102
TMEM176A transmembrane protein 176A -2.34836
SDF2L1 stromal cell-derived factor 2-like 1 -2.34833
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -2.3471
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -2.34654
SNX5 sorting nexin 5 -2.33969
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -2.3385
DENND2D DENN/MADD domain containing 2D -2.33659
CHKA choline kinase alpha -2.33173
FBF1 Fas (TNFRSF6) binding factor 1 -2.33064
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 -2.32832
CKS1B CDC28 protein kinase regulatory subunit 1B -2.32734
ZNF273 zinc finger protein 273 -2.32325
DDAH1 dimethylarginine dimethylaminohydrolase 1 -2.31863
GCH1 GTP cyclohydrolase 1 -2.31482
LOC102724652 alpha-crystallin A chain -2.31153
RRP1B ribosomal RNA processing 1B -2.31084
WDR62 WD repeat domain 62 -2.30966
ABHD11 abhydrolase domain containing 11 -2.30966
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -2.30831
PTBP1 polypyrimidine tract binding protein 1 -2.30797
ASGR2 asialoglycoprotein receptor 2 -2.30665
AP1AR adaptor-related protein complex 1 associated regulatory protein -2.30566
RAD51 RAD51 recombinase -2.30479
STOML2 stomatin (EPB72)-like 2 -2.30213
C4BPA complement component 4 binding protein, alpha -2.3013
CAPN3 calpain 3, (p94) -2.29675
TFF3 trefoil factor 3 (intestinal) -2.29294
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 -2.29117
EXOSC5 exosome component 5 -2.29104
MRPS30 mitochondrial ribosomal protein S30 -2.29057
MAN1A1 mannosidase, alpha, class 1A, member 1 -2.28611
HMGB1 high mobility group box 1 -2.28158
ACYP1 acylphosphatase 1, erythrocyte (common) type -2.28143
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -2.28059
XPO1 exportin 1 -2.28038
PDS5A PDS5 cohesin associated factor A -2.27854
NASP nuclear autoantigenic sperm protein (histone-binding) -2.27593
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.27506
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -2.27502
UGP2 UDP-glucose pyrophosphorylase 2 -2.27381
KIFC1 kinesin family member C1 -2.27341
CER1 cerberus 1, DAN family BMP antagonist -2.27136
ANGPTL8 angiopoietin like 8 -2.26904
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -2.26839
BARX2 BARX homeobox 2 -2.26797
DCT dopachrome tautomerase -2.26587
ENOSF1 enolase superfamily member 1 -2.26551
SCGB2A2 secretoglobin, family 2A, member 2 -2.26249
PRUNE1 prune exopolyphosphatase 1 -2.25825
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -2.25082
RRM1 ribonucleotide reductase M1 -2.24893
ACOX2 acyl-CoA oxidase 2, branched chain -2.24531
MLEC malectin -2.24192
RNF38 ring finger protein 38 -2.23996
CPOX coproporphyrinogen oxidase -2.23928
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -2.23741
APOH apolipoprotein H (beta-2-glycoprotein I) -2.23573
BLM Bloom syndrome, RecQ helicase-like -2.23448
AFM afamin -2.22981
NCAPD2 non-SMC condensin I complex, subunit D2 -2.22943
HPD 4-hydroxyphenylpyruvate dioxygenase -2.22885
CPED1 cadherin-like and PC-esterase domain containing 1 -2.22666
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -2.22652
SERHL2 serine hydrolase-like 2 -2.22498
MYO5C myosin VC -2.22132
CEP83 centrosomal protein 83kDa -2.2193
TMX1 thioredoxin-related transmembrane protein 1 -2.21753
TYR tyrosinase -2.20924
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -2.20923
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -2.20568
DCP2 decapping mRNA 2 -2.19622
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.19561
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.19423
HBG1 hemoglobin, gamma A -2.19291
LRRC59 leucine rich repeat containing 59 -2.1909
TJP3 tight junction protein 3 -2.18903
ATF5 activating transcription factor 5 -2.18845
KRTAP5-2 keratin associated protein 5-2 -2.18733
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.18715
GCA grancalcin, EF-hand calcium binding protein -2.18581
SCAMP4 secretory carrier membrane protein 4 -2.18483
MRPL23 mitochondrial ribosomal protein L23 -2.18262
NAV2 neuron navigator 2 -2.18237
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) -2.18123
ALPL alkaline phosphatase, liver/bone/kidney -2.18038
E2F5 E2F transcription factor 5, p130-binding -2.17863
ERBB3 erb-b2 receptor tyrosine kinase 3 -2.17715
RCC1L RCC1 like -2.17676
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase -2.17052
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 -2.17008
SIRT6 sirtuin 6 -2.16573
PSMC3IP PSMC3 interacting protein -2.16562
ADD3 adducin 3 (gamma) -2.16477
RGN regucalcin -2.16197
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha -2.16055
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -2.15785
KNTC1 kinetochore associated 1 -2.15747
NFE2 nuclear factor, erythroid 2 -2.15698
RFWD3 ring finger and WD repeat domain 3 -2.15698
CENPN centromere protein N -2.15522
SASH1 SAM and SH3 domain containing 1 -2.15152
TIMCC TIM double twin CX3C motif chaperone -2.1496
THOC7 THO complex 7 -2.14921
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -2.14839
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.14812
PUM3 pumilio RNA binding family member 3 -2.14576
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -2.1422
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.14147
SLC19A1 solute carrier family 19 (folate transporter), member 1 -2.14102
TKFC triokinase/FMN cyclase -2.13776
PDGFRL platelet-derived growth factor receptor-like -2.13758
FOXN2 forkhead box N2 -2.13617
C1QBP complement component 1, q subcomponent binding protein -2.13617
MOCS2 molybdenum cofactor synthesis 2 -2.13444
YJU2 YJU2 splicing factor homolog -2.13398
MRPL11 mitochondrial ribosomal protein L11 -2.13129
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.131
ACO1 aconitase 1, soluble -2.12898
GFI1B growth factor independent 1B transcription repressor -2.12564
HDAC6 histone deacetylase 6 -2.12496
TERT telomerase reverse transcriptase -2.12249
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 -2.12096
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like -2.12033
SATB2 SATB homeobox 2 -2.1183
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 -2.11659
CLIP2 CAP-GLY domain containing linker protein 2 -2.11643
LUM lumican -2.11559
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -2.11474
SEPHS1 selenophosphate synthetase 1 -2.10912
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -2.10912
CASP8AP2 caspase 8 associated protein 2 -2.10808
ATAD5 ATPase family, AAA domain containing 5 -2.10686
RAB15 RAB15, member RAS oncogene family -2.1067
MTTP microsomal triglyceride transfer protein -2.09959
ALOX12 arachidonate 12-lipoxygenase -2.09637
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 -2.09571
RECK reversion-inducing-cysteine-rich protein with kazal motifs -2.09403
CASP6 caspase 6, apoptosis-related cysteine peptidase -2.09343
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.08615
PES1 pescadillo ribosomal biogenesis factor 1 -2.08533
STX11 syntaxin 11 -2.08388
PNN pinin, desmosome associated protein -2.08361
ATAD3A ATPase family, AAA domain containing 3A -2.08088
CD36 CD36 molecule (thrombospondin receptor) -2.08043
COL9A3 collagen, type IX, alpha 3 -2.08015
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.07988
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -2.07969
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -2.07836
PRMT1 protein arginine methyltransferase 1 -2.07698
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 -2.07379
SOX10 SRY (sex determining region Y)-box 10 -2.07277
CPB2 carboxypeptidase B2 (plasma) -2.07258
CHPT1 choline phosphotransferase 1 -2.07142
GLDC glycine dehydrogenase (decarboxylating) -2.06958
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.06792
LRRC32 leucine rich repeat containing 32 -2.06666
RHOBTB3 Rho-related BTB domain containing 3 -2.06531
GAS7 growth arrest-specific 7 -2.06519
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.0651
NLE1 notchless homolog 1 (Drosophila) -2.06483
PLIN2 perilipin 2 -2.06397
HMBS hydroxymethylbilane synthase -2.06312
CADPS2 Ca++-dependent secretion activator 2 -2.06312
CHURC1-FNTB CHURC1-FNTB readthrough -2.06306
SAA4 serum amyloid A4, constitutive -2.06281
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like -2.06032
AHSG alpha-2-HS-glycoprotein -2.06026
IDE insulin-degrading enzyme -2.05943
TTF2 transcription termination factor, RNA polymerase II -2.05867
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -2.05458
ZWILCH zwilch kinetochore protein -2.05378
CBX3 chromobox homolog 3 -2.05352
TRA2B transformer 2 beta homolog (Drosophila) -2.05012
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -2.04955
DCXR dicarbonyl/L-xylulose reductase -2.04822
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.04545
ANAPC1 anaphase promoting complex subunit 1 -2.04321
CYBA cytochrome b-245, alpha polypeptide -2.04283
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase -2.04171
GCGR glucagon receptor -2.04136
DMBT1 deleted in malignant brain tumors 1 -2.04112
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.04019
PCDHB13 protocadherin beta 13 -2.03969
COL10A1 collagen, type X, alpha 1 -2.03949
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 -2.03752
FAM76A family with sequence similarity 76, member A -2.03627
GATA4 GATA binding protein 4 -2.03581
NCAPD3 non-SMC condensin II complex, subunit D3 -2.0344
GPD1L glycerol-3-phosphate dehydrogenase 1-like -2.03333
QDPR quinoid dihydropteridine reductase -2.03316
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -2.03263
MMP17 matrix metallopeptidase 17 (membrane-inserted) -2.03023
DPYD dihydropyrimidine dehydrogenase -2.02808
WDR46 WD repeat domain 46 -2.02788
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -2.02742
THBS2 thrombospondin 2 -2.02532
RITA1 RBPJ interacting and tubulin associated 1 -2.02406
EML4 echinoderm microtubule associated protein like 4 -2.02315
PRODH proline dehydrogenase (oxidase) 1 -2.02153
STC2 stanniocalcin 2 -2.02104
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -2.01707
CEP72 centrosomal protein 72kDa -2.01606
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -2.01502
UROS uroporphyrinogen III synthase -2.01416
NOL11 nucleolar protein 11 -2.0139
NDC80 NDC80 kinetochore complex component -2.01307
MACROD1 MACRO domain containing 1 -2.01276
DBR1 debranching RNA lariats 1 -2.01096
LARP1 La ribonucleoprotein domain family, member 1 -2.00915
CENPX centromere protein X -2.00878
ZNF835 zinc finger protein 835 -2.00713
DEK DEK proto-oncogene -2.00496
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.00465