CRCGN009_HEPG2_24H:D06 Gene Set
Genes
42 genes differentially expressed following the CRCGN009_HEPG2_24H:D06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
7.27735
|
|
FZD7
|
frizzled class receptor 7
|
5.16872
|
|
E2F2
|
E2F transcription factor 2
|
4.9371
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.82134
|
|
MOK
|
MOK protein kinase
|
4.74782
|
|
CYCS
|
cytochrome c, somatic
|
3.88865
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.67426
|
|
STIMATE
|
STIM activating enhancer
|
3.43485
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
3.25709
|
|
ZFP36
|
ZFP36 ring finger protein
|
3.18728
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
2.65411
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
2.60347
|
|
SFTPB
|
surfactant protein B
|
2.52616
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.39476
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.36078
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.34621
|
|
GATA2
|
GATA binding protein 2
|
2.29221
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.27682
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.26545
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.20148
|
|
KIF20A
|
kinesin family member 20A
|
2.07726
|
|
PYCR3
|
pyrroline-5-carboxylate reductase 3
|
2.01932
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.01846
|
|
LCN2
|
lipocalin 2
|
2.0078
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-9.40875
|
|
CDC20
|
cell division cycle 20
|
-5.0
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.84211
|
|
LDHD
|
lactate dehydrogenase D
|
-4.78089
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.66961
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.666
|
|
TLR4
|
toll-like receptor 4
|
-3.82338
|
|
ERC2
|
ELKS/RAB6-interacting/CAST family member 2
|
-3.59747
|
|
RNF167
|
ring finger protein 167
|
-2.66541
|
|
HMG20B
|
high mobility group 20B
|
-2.62457
|
|
EGF
|
epidermal growth factor
|
-2.46318
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.3345
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.27494
|
|
PEG10
|
paternally expressed 10
|
-2.20769
|
|
ZNF586
|
zinc finger protein 586
|
-2.13297
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-2.11231
|
|
THAP11
|
THAP domain containing 11
|
-2.0551
|
|
BDKRB2
|
bradykinin receptor B2
|
-2.03608
|