| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | methyl carbamate 20.1 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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74 genes differentially expressed following the CRCGN009_HEPG2_24H:D08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 | 5.11736 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 5.0384 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.6947 |
| JADE2 | jade family PHD finger 2 | 4.29333 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 4.28698 |
| MOK | MOK protein kinase | 4.19263 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.96528 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 3.30595 |
| PRKCH | protein kinase C, eta | 3.16908 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.0187 |
| EPHA3 | EPH receptor A3 | 2.97869 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 2.9634 |
| DOK2 | docking protein 2, 56kDa | 2.91951 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.58029 |
| WDR7 | WD repeat domain 7 | 2.56232 |
| EVL | Enah/Vasp-like | 2.45848 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.40639 |
| TBP | TATA box binding protein | 2.35332 |
| HEBP1 | heme binding protein 1 | 2.32478 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.31891 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.31473 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.25715 |
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 | 2.23986 |
| MAN2B2 | mannosidase, alpha, class 2B, member 2 | 2.20248 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 2.20185 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.16853 |
| CTSL | cathepsin L | 2.15405 |
| DOCK5 | dedicator of cytokinesis 5 | 2.12359 |
| RAB31 | RAB31, member RAS oncogene family | 2.12235 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain | 2.10854 |
| CETP | cholesteryl ester transfer protein, plasma | 2.10821 |
| PLSCR3 | phospholipid scramblase 3 | 2.10477 |
| DRC9 | dynein regulatory complex subunit 9 | 2.09835 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) | 2.0489 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 2.03766 |
| TTC38 | tetratricopeptide repeat domain 38 | 2.01372 |
| DENND1C | DENN/MADD domain containing 1C | 2.0095 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -8.4961 |
| CCNB1 | cyclin B1 | -7.12334 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.36508 |
| DSG2 | desmoglein 2 | -5.20388 |
| YME1L1 | YME1-like 1 ATPase | -5.07946 |
| CD320 | CD320 molecule | -4.72925 |
| PCNA | proliferating cell nuclear antigen | -4.69857 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.6967 |
| PRPF4 | pre-mRNA processing factor 4 | -4.39681 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.26838 |
| ZW10 | zw10 kinetochore protein | -4.14758 |
| GNAS | GNAS complex locus | -3.60954 |
| SMNDC1 | survival motor neuron domain containing 1 | -3.43833 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.41836 |
| PEG10 | paternally expressed 10 | -3.38205 |
| CDC20 | cell division cycle 20 | -3.25167 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.22901 |
| IFRD2 | interferon-related developmental regulator 2 | -3.01295 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.94435 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.82619 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.718 |
| NUDCD3 | NudC domain containing 3 | -2.56525 |
| WASHC4 | WASH complex subunit 4 | -2.42771 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.37469 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.35305 |
| TMEM115 | transmembrane protein 115 | -2.34487 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) | -2.26866 |
| CUL1 | cullin 1 | -2.26817 |
| ZNF274 | zinc finger protein 274 | -2.24649 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.20146 |
| CHEK1 | checkpoint kinase 1 | -2.16324 |
| SLC35F6 | solute carrier family 35, member F6 | -2.11086 |
| CPNE3 | copine III | -2.11014 |
| HEBP2 | heme binding protein 2 | -2.07049 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.06962 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.05992 |
| GDF9 | growth differentiation factor 9 | -2.02481 |
