CRCGN009_HEPG2_24H:D10 Gene Set
Genes
42 genes differentially expressed following the CRCGN009_HEPG2_24H:D10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
6.82904
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
4.355
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.97262
|
|
CBR3
|
carbonyl reductase 3
|
3.94323
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.82672
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.734
|
|
LCN2
|
lipocalin 2
|
3.63209
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.31183
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.29751
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.23088
|
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
3.16596
|
|
CYCS
|
cytochrome c, somatic
|
2.85103
|
|
UBQLN2
|
ubiquilin 2
|
2.71089
|
|
MAP7
|
microtubule-associated protein 7
|
2.54104
|
|
KIF20A
|
kinesin family member 20A
|
2.50988
|
|
GPATCH8
|
G patch domain containing 8
|
2.17315
|
|
CHN1
|
chimerin 1
|
2.14736
|
|
COMMD10
|
COMM domain containing 10
|
2.12566
|
|
PCDHB11
|
protocadherin beta 11
|
2.0797
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.05939
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ADI1
|
acireductone dioxygenase 1
|
-5.67287
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-4.93234
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.50385
|
|
CCNB2
|
cyclin B2
|
-4.26436
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.69886
|
|
DNM1L
|
dynamin 1-like
|
-3.64673
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.45998
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.33055
|
|
CTSD
|
cathepsin D
|
-3.31026
|
|
RAI14
|
retinoic acid induced 14
|
-3.26391
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-3.1725
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.03642
|
|
PEG10
|
paternally expressed 10
|
-2.98753
|
|
RPN1
|
ribophorin I
|
-2.87018
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-2.59498
|
|
GOLT1B
|
golgi transport 1B
|
-2.48112
|
|
TES
|
testin LIM domain protein
|
-2.44624
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-2.39943
|
|
GPR87
|
G protein-coupled receptor 87
|
-2.22246
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.17138
|
|
MVP
|
major vault protein
|
-2.16572
|
|
GNAS
|
GNAS complex locus
|
-2.01661
|