| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | methyl carbamate 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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53 genes differentially expressed following the CRCGN009_HEPG2_24H:D12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAMLD1 | mastermind-like domain containing 1 | 5.16645 |
| UBQLN2 | ubiquilin 2 | 4.93294 |
| ADRB2 | adrenoceptor beta 2, surface | 4.85087 |
| BZW2 | basic leucine zipper and W2 domains 2 | 4.69075 |
| E2F2 | E2F transcription factor 2 | 4.24055 |
| HDGFL3 | HDGF like 3 | 4.02248 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.90954 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.47424 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 3.3947 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 3.20791 |
| MAP7 | microtubule-associated protein 7 | 3.15593 |
| VGLL4 | vestigial-like family member 4 | 3.07115 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.89628 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 2.88761 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 2.8664 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 2.69147 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.64183 |
| GATA2 | GATA binding protein 2 | 2.58722 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 2.53867 |
| BAG4 | BCL2-associated athanogene 4 | 2.22942 |
| CPLX2 | complexin 2 | 2.19078 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 2.16886 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 2.12037 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.10699 |
| CACNG3 | calcium channel, voltage-dependent, gamma subunit 3 | 2.07818 |
| STX1A | syntaxin 1A (brain) | 2.03881 |
| MPPED1 | metallophosphoesterase domain containing 1 | 2.02356 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDC20 | cell division cycle 20 | -6.47594 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.82402 |
| TRIB3 | tribbles pseudokinase 3 | -4.51012 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -4.50496 |
| CCDC86 | coiled-coil domain containing 86 | -4.19032 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.14457 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.91314 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.83917 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.74975 |
| SLC35F2 | solute carrier family 35, member F2 | -3.72996 |
| VAT1 | vesicle amine transport 1 | -3.60168 |
| ANKRD10 | ankyrin repeat domain 10 | -3.42376 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.38816 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -3.24269 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.81265 |
| TLR4 | toll-like receptor 4 | -2.61458 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.41423 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.40532 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.4019 |
| ACBD3 | acyl-CoA binding domain containing 3 | -2.37828 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.32278 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.27451 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.25398 |
| GDF15 | growth differentiation factor 15 | -2.15731 |
| HSPA8 | heat shock 70kDa protein 8 | -2.04805 |
| CCNB1 | cyclin B1 | -2.03047 |
