CRCGN009_HEPG2_24H:D14 Gene Set
Genes
56 genes differentially expressed following the CRCGN009_HEPG2_24H:D14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
7.87537
|
|
STIMATE
|
STIM activating enhancer
|
7.59445
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
5.24532
|
|
PRKCH
|
protein kinase C, eta
|
5.11024
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.9142
|
|
LCN2
|
lipocalin 2
|
3.77826
|
|
INTS3
|
integrator complex subunit 3
|
3.77797
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.62199
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.43114
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.23111
|
|
EPHB2
|
EPH receptor B2
|
3.19792
|
|
MICALL1
|
MICAL-like 1
|
3.1833
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.08063
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.58109
|
|
SFTPB
|
surfactant protein B
|
2.57913
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.48149
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.38068
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
2.37962
|
|
UBQLN2
|
ubiquilin 2
|
2.36778
|
|
EVL
|
Enah/Vasp-like
|
2.36618
|
|
MAP7
|
microtubule-associated protein 7
|
2.3641
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.33946
|
|
POLR2F
|
polymerase (RNA) II (DNA directed) polypeptide F
|
2.28397
|
|
PIGH
|
phosphatidylinositol glycan anchor biosynthesis, class H
|
2.21302
|
|
GINS3
|
GINS complex subunit 3 (Psf3 homolog)
|
2.19928
|
|
NOTCH1
|
notch 1
|
2.09965
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.05662
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.02615
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.002
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-7.52272
|
|
CDC20
|
cell division cycle 20
|
-5.87043
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-4.43016
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.31027
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-4.29198
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.11948
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.97843
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.96181
|
|
PEG10
|
paternally expressed 10
|
-3.744
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.67996
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-3.41948
|
|
CCNB1
|
cyclin B1
|
-3.39915
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.20382
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.20152
|
|
ZNF586
|
zinc finger protein 586
|
-3.0552
|
|
CSK
|
c-src tyrosine kinase
|
-3.01271
|
|
GNAS
|
GNAS complex locus
|
-2.94986
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-2.94626
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.78724
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.64145
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-2.57011
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.56206
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.52635
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-2.51683
|
|
NGLY1
|
N-glycanase 1
|
-2.19882
|
|
AP3S1
|
adaptor-related protein complex 3, sigma 1 subunit
|
-2.05398
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.01647
|
