| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | acrolein 1.28 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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80 genes differentially expressed following the CRCGN009_HEPG2_24H:D18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL39L | ribosomal protein L39-like | 10.0 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 7.92171 |
| MYLK | myosin light chain kinase | 6.82853 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 5.24081 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.04704 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.88009 |
| MAP7 | microtubule-associated protein 7 | 4.82014 |
| E2F2 | E2F transcription factor 2 | 4.77374 |
| RAB21 | RAB21, member RAS oncogene family | 4.49735 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 4.47354 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 4.35601 |
| PMM2 | phosphomannomutase 2 | 4.34558 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.27179 |
| FZD7 | frizzled class receptor 7 | 4.22343 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 3.59601 |
| CYCS | cytochrome c, somatic | 3.54923 |
| RXYLT1 | ribitol xylosyltransferase 1 | 3.44227 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 3.20727 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.0823 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.9364 |
| TBPL1 | TBP-like 1 | 2.83017 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 2.77301 |
| FZD1 | frizzled class receptor 1 | 2.66497 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.57367 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.51463 |
| CCNA1 | cyclin A1 | 2.4346 |
| SEPHS1 | selenophosphate synthetase 1 | 2.42458 |
| SOX30 | SRY (sex determining region Y)-box 30 | 2.35772 |
| OPTN | optineurin | 2.32614 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 2.29652 |
| MILR1 | mast cell immunoglobulin-like receptor 1 | 2.22925 |
| PDSS1 | prenyl (decaprenyl) diphosphate synthase, subunit 1 | 2.17853 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.17764 |
| SYNPO2L | synaptopodin 2-like | 2.15984 |
| OCA2 | oculocutaneous albinism II | 2.11536 |
| TEX10 | testis expressed 10 | 2.10806 |
| EPHA1 | EPH receptor A1 | 2.09532 |
| KIF16B | kinesin family member 16B | 2.08729 |
| RNF32 | ring finger protein 32 | 2.03948 |
| RBMXL2 | RNA binding motif protein, X-linked-like 2 | 2.03772 |
| RBM47 | RNA binding motif protein 47 | 2.02646 |
| GSG1 | germ cell associated 1 | 2.00481 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GDF15 | growth differentiation factor 15 | -6.46791 |
| CCNB2 | cyclin B2 | -6.10721 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.28295 |
| UBE3C | ubiquitin protein ligase E3C | -5.01092 |
| CCDC86 | coiled-coil domain containing 86 | -4.97903 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.8123 |
| DNM1L | dynamin 1-like | -4.5823 |
| CSK | c-src tyrosine kinase | -4.52207 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -4.43185 |
| GNAS | GNAS complex locus | -3.85811 |
| NGRN | neugrin, neurite outgrowth associated | -3.8451 |
| SNX11 | sorting nexin 11 | -3.65268 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -3.29165 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.19766 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.13759 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.08485 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.97149 |
| TXNDC9 | thioredoxin domain containing 9 | -2.94282 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.89766 |
| RNF167 | ring finger protein 167 | -2.89058 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.7225 |
| SCCPDH | saccharopine dehydrogenase (putative) | -2.54038 |
| CDC20 | cell division cycle 20 | -2.50763 |
| SLC35F2 | solute carrier family 35, member F2 | -2.41351 |
| ARL17B | ADP-ribosylation factor-like 17B | -2.32672 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -2.29158 |
| HMG20B | high mobility group 20B | -2.2617 |
| CHST10 | carbohydrate sulfotransferase 10 | -2.23343 |
| KYAT3 | kynurenine aminotransferase 3 | -2.2296 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.22401 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -2.19723 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.16735 |
| HAT1 | histone acetyltransferase 1 | -2.142 |
| ANKRD10 | ankyrin repeat domain 10 | -2.11917 |
| USP3 | ubiquitin specific peptidase 3 | -2.08787 |
| RANBP6 | RAN binding protein 6 | -2.06799 |
| SF3A3 | splicing factor 3a, subunit 3, 60kDa | -2.04901 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.00209 |
