CRCGN009_HEPG2_24H:D21 Gene Set
Genes
55 genes differentially expressed following the CRCGN009_HEPG2_24H:D21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
4.74005
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.61303
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.50052
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
4.36329
|
|
EPHB2
|
EPH receptor B2
|
4.34816
|
|
STK10
|
serine/threonine kinase 10
|
3.69693
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.58373
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.55224
|
|
PRKCH
|
protein kinase C, eta
|
3.17537
|
|
STIMATE
|
STIM activating enhancer
|
3.16735
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.15792
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.90313
|
|
PRR15L
|
proline rich 15-like
|
2.73488
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.64591
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.61644
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.58236
|
|
EVL
|
Enah/Vasp-like
|
2.50351
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.41588
|
|
KIF5C
|
kinesin family member 5C
|
2.23025
|
|
CCNF
|
cyclin F
|
2.19252
|
|
GPATCH8
|
G patch domain containing 8
|
2.08358
|
|
ZNF552
|
zinc finger protein 552
|
2.05907
|
|
HBG1
|
hemoglobin, gamma A
|
2.03021
|
|
CYP2C18
|
cytochrome P450, family 2, subfamily C, polypeptide 18
|
2.01283
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.00925
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.37461
|
|
COG2
|
component of oligomeric golgi complex 2
|
-5.26105
|
|
DNM1L
|
dynamin 1-like
|
-4.64256
|
|
PEG10
|
paternally expressed 10
|
-4.15294
|
|
GNAS
|
GNAS complex locus
|
-4.11359
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.90733
|
|
GADD45A
|
growth arrest and DNA-damage-inducible, alpha
|
-3.8675
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.83428
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.79511
|
|
SMNDC1
|
survival motor neuron domain containing 1
|
-3.62851
|
|
CCNB2
|
cyclin B2
|
-3.29131
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.19935
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.19389
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.14275
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-3.09453
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.05136
|
|
SPAG4
|
sperm associated antigen 4
|
-3.04845
|
|
CPNE3
|
copine III
|
-2.94705
|
|
CD320
|
CD320 molecule
|
-2.90641
|
|
ENOPH1
|
enolase-phosphatase 1
|
-2.87181
|
|
CCNH
|
cyclin H
|
-2.82491
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.794
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.69178
|
|
PROS1
|
protein S (alpha)
|
-2.6105
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.55691
|
|
NVL
|
nuclear VCP-like
|
-2.2607
|
|
CDC20
|
cell division cycle 20
|
-2.13261
|
|
DKK1
|
dickkopf WNT signaling pathway inhibitor 1
|
-2.06479
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.04011
|
|
SLC15A2
|
solute carrier family 15 (oligopeptide transporter), member 2
|
-2.00402
|
