CRCGN009_HEPG2_24H:D23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tris(1-chloro-2-propanyl) phosphate 2.5 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN009_HEPG2_24H:D23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
C2CD2 C2 calcium-dependent domain containing 2 5.49817
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.47414
CHMP6 charged multivesicular body protein 6 4.46489
MAP7 microtubule-associated protein 7 4.45347
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.99614
EAPP E2F-associated phosphoprotein 3.97913
KLHL9 kelch-like family member 9 3.48137
ABHD6 abhydrolase domain containing 6 3.467
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 3.11586
ADAM10 ADAM metallopeptidase domain 10 2.78513
PFKL phosphofructokinase, liver 2.70704
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.59635
CCNF cyclin F 2.34859
CTTN cortactin 2.28792
CCL2 chemokine (C-C motif) ligand 2 2.27562
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.27097

decreased expression

Symbol Name Standardized Value
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -8.24518
CCNB2 cyclin B2 -6.74495
PCNA proliferating cell nuclear antigen -5.89464
LDHD lactate dehydrogenase D -5.75971
HAT1 histone acetyltransferase 1 -4.40049
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.89013
OXA1L oxidase (cytochrome c) assembly 1-like -3.51048
TLCD3A TLC domain containing 3A -3.40702
VDAC1 voltage-dependent anion channel 1 -2.9387
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.56497
FABP5 fatty acid binding protein 5 (psoriasis-associated) -2.41635
CCNB1 cyclin B1 -2.22582
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.06821