| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | norethindrone 10.28 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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59 genes differentially expressed following the CRCGN009_HEPG2_24H:E02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 9.39549 |
| MAP7 | microtubule-associated protein 7 | 6.80947 |
| CBR3 | carbonyl reductase 3 | 5.01796 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.84134 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.75607 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.64238 |
| CHMP6 | charged multivesicular body protein 6 | 4.59043 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.68693 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 3.34032 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.86016 |
| MCM3 | minichromosome maintenance complex component 3 | 2.79091 |
| TBC1D31 | TBC1 domain family, member 31 | 2.60414 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.59242 |
| PON3 | paraoxonase 3 | 2.46002 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 2.39383 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 2.36644 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 2.33752 |
| DIPK1A | divergent protein kinase domain 1A | 2.30972 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 2.27587 |
| RIGI | RNA sensor RIG-I | 2.22322 |
| MRPS2 | mitochondrial ribosomal protein S2 | 2.18683 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 2.17888 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 2.16483 |
| SATB1 | SATB homeobox 1 | 2.14952 |
| TBKBP1 | TBK1 binding protein 1 | 2.08103 |
| IFI6 | interferon, alpha-inducible protein 6 | 2.0706 |
| IFI44 | interferon-induced protein 44 | 2.02396 |
| JADE2 | jade family PHD finger 2 | 2.01275 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -5.58185 |
| PRPF4 | pre-mRNA processing factor 4 | -5.06278 |
| TCTN1 | tectonic family member 1 | -4.89593 |
| TLR4 | toll-like receptor 4 | -4.57695 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -4.46612 |
| LOC124907782 | dual specificity protein phosphatase 22 | -4.44168 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -4.39749 |
| ADI1 | acireductone dioxygenase 1 | -4.32964 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.22442 |
| GNAS | GNAS complex locus | -4.06257 |
| PCNA | proliferating cell nuclear antigen | -4.00247 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -3.72421 |
| BIRC2 | baculoviral IAP repeat containing 2 | -3.67869 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -3.50259 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.33043 |
| CCNB2 | cyclin B2 | -3.17718 |
| TLCD3A | TLC domain containing 3A | -3.05232 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.93183 |
| EGF | epidermal growth factor | -2.87872 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.45839 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -2.45313 |
| KIAA0232 | KIAA0232 | -2.40545 |
| CETN2 | centrin, EF-hand protein, 2 | -2.36586 |
| DCK | deoxycytidine kinase | -2.36235 |
| ILK | integrin-linked kinase | -2.2887 |
| LYRM1 | LYR motif containing 1 | -2.25475 |
| WASHC4 | WASH complex subunit 4 | -2.18244 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.09379 |
| SNX11 | sorting nexin 11 | -2.08732 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -2.0486 |
