| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | norethindrone 5.14 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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74 genes differentially expressed following the CRCGN009_HEPG2_24H:E03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 10.0 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.79681 |
| MAP7 | microtubule-associated protein 7 | 5.11428 |
| UBQLN2 | ubiquilin 2 | 4.37803 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.07437 |
| STIMATE | STIM activating enhancer | 3.95906 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.89724 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.59368 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.9228 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 2.91368 |
| CCNH | cyclin H | 2.89555 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.88278 |
| ABHD6 | abhydrolase domain containing 6 | 2.74335 |
| FABP4 | fatty acid binding protein 4, adipocyte | 2.59787 |
| NOTCH1 | notch 1 | 2.54167 |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa | 2.46819 |
| HOOK2 | hook microtubule-tethering protein 2 | 2.43077 |
| HSPA1A | heat shock 70kDa protein 1A | 2.41848 |
| HILPDA | hypoxia inducible lipid droplet-associated | 2.40583 |
| ECD | ecdysoneless homolog (Drosophila) | 2.29185 |
| MCM3 | minichromosome maintenance complex component 3 | 2.25822 |
| MEST | mesoderm specific transcript | 2.23693 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 2.23077 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 2.20896 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 2.19092 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 2.13876 |
| TENT4A | terminal nucleotidyltransferase 4A | 2.11951 |
| SH3D19 | SH3 domain containing 19 | 2.09081 |
| PRR15L | proline rich 15-like | 2.07722 |
| SYNGR2 | synaptogyrin 2 | 2.07531 |
| STXBP2 | syntaxin binding protein 2 | 2.05775 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -6.44753 |
| TLR4 | toll-like receptor 4 | -5.61736 |
| TCTN1 | tectonic family member 1 | -4.64107 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -4.41138 |
| CCNB2 | cyclin B2 | -4.2422 |
| ZNF586 | zinc finger protein 586 | -3.8847 |
| COG2 | component of oligomeric golgi complex 2 | -3.60544 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.58913 |
| PLK1 | polo-like kinase 1 | -3.44781 |
| RNF167 | ring finger protein 167 | -3.32893 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -3.24132 |
| EGF | epidermal growth factor | -3.2403 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.20029 |
| YME1L1 | YME1-like 1 ATPase | -3.19007 |
| GOLT1B | golgi transport 1B | -3.17509 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -3.0333 |
| GNAS | GNAS complex locus | -2.90925 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.87259 |
| PEG10 | paternally expressed 10 | -2.78548 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -2.6869 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.68466 |
| LDHD | lactate dehydrogenase D | -2.63313 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -2.50132 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.41743 |
| NPPA | natriuretic peptide A | -2.36657 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.27575 |
| ARSF | arylsulfatase F | -2.23638 |
| HAX1 | HCLS1 associated protein X-1 | -2.19212 |
| CDC25B | cell division cycle 25B | -2.17165 |
| KIF5B | kinesin family member 5B | -2.16765 |
| CD82 | CD82 molecule | -2.166 |
| ZW10 | zw10 kinetochore protein | -2.14465 |
| BPI | bactericidal/permeability-increasing protein | -2.14333 |
| WDR37 | WD repeat domain 37 | -2.07844 |
| HOOK3 | hook microtubule-tethering protein 3 | -2.07143 |
| MMP8 | matrix metallopeptidase 8 | -2.07128 |
| ADA2 | adenosine deaminase 2 | -2.04699 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.04363 |
| GP9 | glycoprotein IX (platelet) | -2.02422 |
| FUZ | fuzzy planar cell polarity protein | -2.01208 |
| KIAA1614 | KIAA1614 | -2.01079 |
| SIRT2 | sirtuin 2 | -2.00307 |
| FGF6 | fibroblast growth factor 6 | -2.00302 |
