| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | norethindrone 2.57 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
58 genes differentially expressed following the CRCGN009_HEPG2_24H:E04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 5.56871 |
| HEBP1 | heme binding protein 1 | 5.13308 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.16189 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.98001 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.88669 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.70522 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.68671 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.52467 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.50139 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.45096 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.36221 |
| CYCS | cytochrome c, somatic | 3.23282 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.1699 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.0046 |
| PFKL | phosphofructokinase, liver | 2.92461 |
| AMDHD2 | amidohydrolase domain containing 2 | 2.91684 |
| MAP7 | microtubule-associated protein 7 | 2.73313 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 2.54923 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.48791 |
| PIH1D1 | PIH1 domain containing 1 | 2.46619 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.4468 |
| LCN2 | lipocalin 2 | 2.41619 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 2.37263 |
| APP | amyloid beta (A4) precursor protein | 2.29503 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 2.27734 |
| CCNF | cyclin F | 2.19964 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.16649 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.15216 |
| HSPA1A | heat shock 70kDa protein 1A | 2.12775 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.11593 |
| KLHL9 | kelch-like family member 9 | 2.11449 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | 2.03187 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -7.36984 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -6.10914 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.08568 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -5.80699 |
| CCNB2 | cyclin B2 | -5.76727 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -4.62995 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -3.90447 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.6431 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.38089 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -3.28257 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.1725 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -3.05252 |
| SPAG4 | sperm associated antigen 4 | -2.92979 |
| SLC35F2 | solute carrier family 35, member F2 | -2.77898 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.72498 |
| UGDH | UDP-glucose 6-dehydrogenase | -2.69288 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.66782 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.64636 |
| ZNF586 | zinc finger protein 586 | -2.62386 |
| RNF167 | ring finger protein 167 | -2.61829 |
| PCNA | proliferating cell nuclear antigen | -2.5809 |
| GNAS | GNAS complex locus | -2.50708 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.33563 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -2.33476 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.03559 |
| TLCD3A | TLC domain containing 3A | -2.02128 |
