| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | norethindrone 0.64 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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57 genes differentially expressed following the CRCGN009_HEPG2_24H:E06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 7.36556 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.30696 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 4.56354 |
| STK10 | serine/threonine kinase 10 | 4.53463 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.17137 |
| STIMATE | STIM activating enhancer | 4.1044 |
| MSRA | methionine sulfoxide reductase A | 4.03273 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.97382 |
| CHMP6 | charged multivesicular body protein 6 | 3.96318 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.93022 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.77861 |
| EPN2 | epsin 2 | 3.59744 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 3.58288 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.46222 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.27275 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.23305 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 3.22233 |
| CCNF | cyclin F | 3.21059 |
| PLS1 | plastin 1 | 3.18745 |
| ABHD6 | abhydrolase domain containing 6 | 3.05334 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 3.00883 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.88875 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.85652 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.71112 |
| CHN1 | chimerin 1 | 2.62169 |
| PCDHB11 | protocadherin beta 11 | 2.52116 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.33286 |
| SLC35H1 | solute carrier family 35 member H1 | 2.31831 |
| KLHL11 | kelch-like family member 11 | 2.17048 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 | 2.13731 |
| PRSS3 | protease, serine, 3 | 2.1223 |
| HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 | 2.01442 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB1 | cyclin B1 | -7.77718 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -7.33243 |
| PCNA | proliferating cell nuclear antigen | -5.47889 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -5.02837 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -4.39053 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.38011 |
| CDC20 | cell division cycle 20 | -4.3489 |
| CCDC86 | coiled-coil domain containing 86 | -4.32698 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.26502 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.25198 |
| CTSD | cathepsin D | -3.90459 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.49798 |
| CSK | c-src tyrosine kinase | -2.89833 |
| LRRC41 | leucine rich repeat containing 41 | -2.71972 |
| PEG10 | paternally expressed 10 | -2.65506 |
| SESN1 | sestrin 1 | -2.52991 |
| HABP2 | hyaluronan binding protein 2 | -2.41847 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -2.39757 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.36391 |
| HMG20B | high mobility group 20B | -2.2664 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.23124 |
| ERI3 | ERI1 exoribonuclease family member 3 | -2.06066 |
| SF3B4 | splicing factor 3b, subunit 4, 49kDa | -2.04256 |
| RNF167 | ring finger protein 167 | -2.03319 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.03242 |
