| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | o,o-diethyl o-(4-nitrophenyl) thiophosphate 5.31 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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60 genes differentially expressed following the CRCGN009_HEPG2_24H:E09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6.94636 |
| PLS1 | plastin 1 | 4.83373 |
| MAP7 | microtubule-associated protein 7 | 4.4645 |
| MAMLD1 | mastermind-like domain containing 1 | 4.37919 |
| UBQLN2 | ubiquilin 2 | 4.15873 |
| MOK | MOK protein kinase | 3.83912 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.69489 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.59415 |
| PRR15L | proline rich 15-like | 3.59013 |
| MYLK | myosin light chain kinase | 3.52641 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.49597 |
| LCN2 | lipocalin 2 | 3.49135 |
| JADE2 | jade family PHD finger 2 | 3.21022 |
| TBC1D10C | TBC1 domain family, member 10C | 3.01892 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.98506 |
| RPL39L | ribosomal protein L39-like | 2.98163 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.94592 |
| DIPK1A | divergent protein kinase domain 1A | 2.91273 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 2.87364 |
| ZNF589 | zinc finger protein 589 | 2.81689 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.73793 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.69925 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.43184 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.42882 |
| TRIM13 | tripartite motif containing 13 | 2.30805 |
| SORBS3 | sorbin and SH3 domain containing 3 | 2.22959 |
| CYCS | cytochrome c, somatic | 2.21422 |
| ISOC1 | isochorismatase domain containing 1 | 2.1989 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 2.14557 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.09718 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.25766 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.81994 |
| TUBB6 | tubulin, beta 6 class V | -3.78568 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.69036 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.6547 |
| VAT1 | vesicle amine transport 1 | -3.6387 |
| SLC35F2 | solute carrier family 35, member F2 | -3.6101 |
| LOC124907782 | dual specificity protein phosphatase 22 | -3.39215 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -3.27022 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.20367 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.20326 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.14335 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.04255 |
| PCNA | proliferating cell nuclear antigen | -3.01688 |
| CD58 | CD58 molecule | -2.9913 |
| GNAS | GNAS complex locus | -2.98975 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -2.86205 |
| CCDC92 | coiled-coil domain containing 92 | -2.7467 |
| GLOD4 | glyoxalase domain containing 4 | -2.69418 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.64822 |
| TLR4 | toll-like receptor 4 | -2.57222 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.54867 |
| TP53BP2 | tumor protein p53 binding protein 2 | -2.46917 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.46028 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -2.28287 |
| ZW10 | zw10 kinetochore protein | -2.222 |
| HEATR1 | HEAT repeat containing 1 | -2.16129 |
| EGF | epidermal growth factor | -2.08459 |
| RPS5 | ribosomal protein S5 | -2.06963 |
| ZNF586 | zinc finger protein 586 | -2.01134 |
