| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | o,o-diethyl o-(4-nitrophenyl) thiophosphate 2.65 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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58 genes differentially expressed following the CRCGN009_HEPG2_24H:E10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| E2F2 | E2F transcription factor 2 | 5.64049 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 5.50713 |
| MYLK | myosin light chain kinase | 5.16184 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.78285 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 4.56402 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.43401 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.26135 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.11283 |
| CCNA1 | cyclin A1 | 4.0912 |
| TBPL1 | TBP-like 1 | 3.98134 |
| PLSCR3 | phospholipid scramblase 3 | 3.46516 |
| FZD7 | frizzled class receptor 7 | 3.27355 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.08586 |
| HEBP1 | heme binding protein 1 | 2.95085 |
| RAB4A | RAB4A, member RAS oncogene family | 2.65207 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.65157 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 2.55494 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 2.5502 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 2.49988 |
| EPHA3 | EPH receptor A3 | 2.47598 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.40426 |
| PRR15L | proline rich 15-like | 2.29437 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.26455 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 | 2.21623 |
| ISL1 | ISL LIM homeobox 1 | 2.20215 |
| DIPK1A | divergent protein kinase domain 1A | 2.16254 |
| TSPAN31 | tetraspanin 31 | 2.07668 |
| F13B | coagulation factor XIII, B polypeptide | 2.05859 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 2.0515 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase | 2.05132 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 2.02646 |
| ZNF140 | zinc finger protein 140 | 2.02527 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -5.10046 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.07549 |
| CDC20 | cell division cycle 20 | -4.67423 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -4.42635 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.41985 |
| LDHD | lactate dehydrogenase D | -4.40653 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.26794 |
| ADI1 | acireductone dioxygenase 1 | -4.14611 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.99208 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.90563 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.78608 |
| GNAS | GNAS complex locus | -3.77309 |
| CSK | c-src tyrosine kinase | -3.75776 |
| CCNB2 | cyclin B2 | -3.71959 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.52651 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.20895 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.54314 |
| STX4 | syntaxin 4 | -2.22793 |
| NCK2 | NCK adaptor protein 2 | -2.16209 |
| PPOX | protoporphyrinogen oxidase | -2.1585 |
| CHGB | chromogranin B | -2.11241 |
| TFRC | transferrin receptor | -2.11027 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.1057 |
| IFRD1 | interferon-related developmental regulator 1 | -2.07456 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.06732 |
| PRPF4 | pre-mRNA processing factor 4 | -2.02742 |
