| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | o,o-diethyl o-(4-nitrophenyl) thiophosphate 1.33 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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49 genes differentially expressed following the CRCGN009_HEPG2_24H:E11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 6.50051 |
| ADRB2 | adrenoceptor beta 2, surface | 6.33889 |
| CYCS | cytochrome c, somatic | 6.10084 |
| LCN2 | lipocalin 2 | 6.08684 |
| MYLK | myosin light chain kinase | 4.4243 |
| UBQLN2 | ubiquilin 2 | 4.0886 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.01436 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.65463 |
| ABHD4 | abhydrolase domain containing 4 | 3.63494 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.48425 |
| DIPK1A | divergent protein kinase domain 1A | 3.29601 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.99349 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 2.83102 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.63909 |
| TBP | TATA box binding protein | 2.57102 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.31462 |
| CPVL | carboxypeptidase, vitellogenic-like | 2.27545 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.26203 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.15476 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 2.14514 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.12032 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.06049 |
| ACY1 | aminoacylase 1 | 2.01382 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 2.00862 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -5.73434 |
| ZNF586 | zinc finger protein 586 | -4.58183 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.51107 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.78449 |
| FASTKD5 | FAST kinase domains 5 | -3.72506 |
| LDHD | lactate dehydrogenase D | -3.48143 |
| CD320 | CD320 molecule | -3.47221 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.43255 |
| NUP85 | nucleoporin 85kDa | -3.2176 |
| EIF5 | eukaryotic translation initiation factor 5 | -3.13692 |
| GNAS | GNAS complex locus | -2.82482 |
| PCNA | proliferating cell nuclear antigen | -2.75712 |
| RAI14 | retinoic acid induced 14 | -2.73884 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.73771 |
| TXNRD1 | thioredoxin reductase 1 | -2.59594 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.39484 |
| CCNB1 | cyclin B1 | -2.34379 |
| DNM1L | dynamin 1-like | -2.32428 |
| RGS2 | regulator of G-protein signaling 2 | -2.28056 |
| SNX11 | sorting nexin 11 | -2.22781 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.19853 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.11689 |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 | -2.10511 |
| FGF4 | fibroblast growth factor 4 | -2.10127 |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) | -2.09557 |
