CRCGN009_HEPG2_24H:E12 Gene Set
Genes
45 genes differentially expressed following the CRCGN009_HEPG2_24H:E12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
6.90274
|
|
MAP7
|
microtubule-associated protein 7
|
4.58851
|
|
VGLL4
|
vestigial-like family member 4
|
4.40686
|
|
RPL39L
|
ribosomal protein L39-like
|
4.0909
|
|
INTS3
|
integrator complex subunit 3
|
3.90965
|
|
LCN2
|
lipocalin 2
|
3.65753
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
3.56271
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.47431
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.27252
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.6657
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.6089
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.48619
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.42914
|
|
DEAF1
|
DEAF1 transcription factor
|
2.3117
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.19553
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.14796
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
2.14356
|
|
SIRT3
|
sirtuin 3
|
2.04584
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.03741
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
2.02597
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
2.01385
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.8212
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-6.2627
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-4.83925
|
|
TLR4
|
toll-like receptor 4
|
-4.70609
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.65592
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-3.48472
|
|
TMEM109
|
transmembrane protein 109
|
-3.46962
|
|
DNM1L
|
dynamin 1-like
|
-3.25954
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.23135
|
|
ZNF586
|
zinc finger protein 586
|
-3.06332
|
|
GDF15
|
growth differentiation factor 15
|
-3.049
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.00402
|
|
ENOPH1
|
enolase-phosphatase 1
|
-2.88977
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.85819
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.76808
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.53369
|
|
CSK
|
c-src tyrosine kinase
|
-2.50977
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.48919
|
|
CCNB2
|
cyclin B2
|
-2.32737
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.21039
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.15996
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.14555
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.09978
|
|
RTL8C
|
retrotransposon Gag like 8C
|
-2.01376
|
