CRCGN009_HEPG2_24H:E15 Gene Set
Genes
44 genes differentially expressed following the CRCGN009_HEPG2_24H:E15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
5.58968
|
|
MYLK
|
myosin light chain kinase
|
3.94078
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
3.8496
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
3.8274
|
|
CBR3
|
carbonyl reductase 3
|
3.80246
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.56099
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.38125
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.34995
|
|
CYCS
|
cytochrome c, somatic
|
3.29166
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
3.25533
|
|
MAP7
|
microtubule-associated protein 7
|
2.95834
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.89872
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.70684
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.56351
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.56303
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.48427
|
|
ALAS1
|
5'-aminolevulinate synthase 1
|
2.47805
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.47389
|
|
STK10
|
serine/threonine kinase 10
|
2.4708
|
|
HEBP1
|
heme binding protein 1
|
2.4436
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.41343
|
|
EPN2
|
epsin 2
|
2.40125
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.28512
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.09469
|
|
ZNF589
|
zinc finger protein 589
|
2.06119
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-7.59605
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.06412
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-4.00308
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.92241
|
|
LDHD
|
lactate dehydrogenase D
|
-3.76655
|
|
SMNDC1
|
survival motor neuron domain containing 1
|
-3.39635
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.22587
|
|
PSRC1
|
proline/serine-rich coiled-coil 1
|
-2.96561
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.80452
|
|
CCNB2
|
cyclin B2
|
-2.61686
|
|
TLR4
|
toll-like receptor 4
|
-2.60164
|
|
WASHC4
|
WASH complex subunit 4
|
-2.49118
|
|
AKAP8
|
A kinase (PRKA) anchor protein 8
|
-2.32213
|
|
SNX11
|
sorting nexin 11
|
-2.26343
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.14279
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-2.14159
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.09654
|
|
ZW10
|
zw10 kinetochore protein
|
-2.09244
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.02534
|
