CRCGN009_HEPG2_24H:E17 Gene Set
Genes
42 genes differentially expressed following the CRCGN009_HEPG2_24H:E17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
6.19906
|
|
CHMP6
|
charged multivesicular body protein 6
|
5.11133
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.85661
|
|
ZNF589
|
zinc finger protein 589
|
4.32572
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.98028
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
3.97297
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
3.62133
|
|
CYCS
|
cytochrome c, somatic
|
3.57311
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.50155
|
|
LCN2
|
lipocalin 2
|
3.39035
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.38182
|
|
GATA2
|
GATA binding protein 2
|
2.8085
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.79367
|
|
CCNF
|
cyclin F
|
2.7431
|
|
CBR3
|
carbonyl reductase 3
|
2.64254
|
|
JADE2
|
jade family PHD finger 2
|
2.57961
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.47525
|
|
MAP7
|
microtubule-associated protein 7
|
2.45849
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.44516
|
|
GPATCH8
|
G patch domain containing 8
|
2.44296
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.36539
|
|
NPR2
|
natriuretic peptide receptor 2
|
2.20038
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.19417
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.19014
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.14902
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
2.13937
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-4.74393
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.72865
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.50225
|
|
EGF
|
epidermal growth factor
|
-3.67173
|
|
CDC20
|
cell division cycle 20
|
-3.4697
|
|
TLR4
|
toll-like receptor 4
|
-3.26355
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.25806
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.09922
|
|
SNX11
|
sorting nexin 11
|
-2.97087
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.78138
|
|
GNAS
|
GNAS complex locus
|
-2.62625
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.57603
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.40868
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-2.25242
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.17815
|
|
USP6NL
|
USP6 N-terminal like
|
-2.11961
|
