CRCGN009_HEPG2_24H:E18 Gene Set
Genes
50 genes differentially expressed following the CRCGN009_HEPG2_24H:E18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ADRB2
|
adrenoceptor beta 2, surface
|
6.6596
|
|
MYLK
|
myosin light chain kinase
|
5.03738
|
|
TBPL1
|
TBP-like 1
|
4.93432
|
|
TATDN2
|
TatD DNase domain containing 2
|
4.6842
|
|
INTS3
|
integrator complex subunit 3
|
4.67266
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
4.53448
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.83367
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.78098
|
|
EPN2
|
epsin 2
|
3.76059
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.6671
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.60816
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.54963
|
|
CYCS
|
cytochrome c, somatic
|
3.43978
|
|
SFTPB
|
surfactant protein B
|
3.13334
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.12956
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.12053
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.88432
|
|
JADE2
|
jade family PHD finger 2
|
2.62277
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.61583
|
|
CBR3
|
carbonyl reductase 3
|
2.41805
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.40331
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.36654
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.31611
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
2.28054
|
|
E2F2
|
E2F transcription factor 2
|
2.2172
|
|
KIF20A
|
kinesin family member 20A
|
2.21615
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLR4
|
toll-like receptor 4
|
-5.98198
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.01249
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.84271
|
|
CCNB2
|
cyclin B2
|
-4.55356
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-4.48195
|
|
LDHD
|
lactate dehydrogenase D
|
-4.45806
|
|
TUBB6
|
tubulin, beta 6 class V
|
-4.17922
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.16885
|
|
TSPAN4
|
tetraspanin 4
|
-3.95706
|
|
GNAS
|
GNAS complex locus
|
-3.39067
|
|
DNM1L
|
dynamin 1-like
|
-3.30818
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.23777
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.11664
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.99162
|
|
PEG10
|
paternally expressed 10
|
-2.95016
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.90584
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.58158
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-2.50579
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.44049
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.40615
|
|
GPKOW
|
G patch domain and KOW motifs
|
-2.24064
|
|
GLT8D2
|
glycosyltransferase 8 domain containing 2
|
-2.14617
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.07023
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.00923
|
