CRCGN009_HEPG2_24H:F03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description potassium 1h-indol-3-yl sulfate 5.43 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

502 genes differentially expressed following the CRCGN009_HEPG2_24H:F03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
UBQLN2 ubiquilin 2 10.0
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 10.0
VAT1 vesicle amine transport 1 7.6308
ADRB2 adrenoceptor beta 2, surface 7.38855
BTK Bruton agammaglobulinemia tyrosine kinase 7.1218
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 7.07
RPL39L ribosomal protein L39-like 7.03595
CHMP6 charged multivesicular body protein 6 6.99815
SQOR sulfide quinone oxidoreductase 6.9162
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 6.64065
MOK MOK protein kinase 6.3341
BACE2 beta-site APP-cleaving enzyme 2 6.32385
SYNE2 spectrin repeat containing, nuclear envelope 2 6.19365
C2CD2 C2 calcium-dependent domain containing 2 5.8963
GATA3 GATA binding protein 3 5.86702
TXNRD1 thioredoxin reductase 1 5.6185
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 5.4057
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 5.25145
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 5.24106
CCL2 chemokine (C-C motif) ligand 2 5.15345
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 4.9641
ABHD4 abhydrolase domain containing 4 4.9511
CASP2 caspase 2, apoptosis-related cysteine peptidase 4.90242
MVP major vault protein 4.88035
HLA-DMA major histocompatibility complex, class II, DM alpha 4.83815
SNAP25 synaptosomal-associated protein, 25kDa 4.75535
LPAR2 lysophosphatidic acid receptor 2 4.72075
ZFP36 ZFP36 ring finger protein 4.59935
EPHA3 EPH receptor A3 4.56755
TBPL1 TBP-like 1 4.5357
CBR1 carbonyl reductase 1 4.52605
CBR3 carbonyl reductase 3 4.52385
PRKCH protein kinase C, eta 4.42992
RAP1GAP RAP1 GTPase activating protein 4.41685
TGFB3 transforming growth factor, beta 3 4.3905
GSTZ1 glutathione S-transferase zeta 1 4.26615
HOXA10 homeobox A10 4.22818
BCL7B B-cell CLL/lymphoma 7B 4.19575
CXCL2 chemokine (C-X-C motif) ligand 2 4.10805
GARRE1 granule associated Rac and RHOG effector 1 4.10695
SATB1 SATB homeobox 1 4.0827
CNPY3 canopy FGF signaling regulator 3 4.0328
CXCR4 chemokine (C-X-C motif) receptor 4 4.03142
PHKA1 phosphorylase kinase, alpha 1 (muscle) 3.9217
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 3.83315
GLI2 GLI family zinc finger 2 3.78307
CRYZ crystallin, zeta (quinone reductase) 3.6807
UGDH UDP-glucose 6-dehydrogenase 3.6325
ANO10 anoctamin 10 3.61485
ALDOC aldolase C, fructose-bisphosphate 3.60485
MAP7 microtubule-associated protein 7 3.50292
STAP2 signal transducing adaptor family member 2 3.44835
TIMP2 TIMP metallopeptidase inhibitor 2 3.4329
TEX10 testis expressed 10 3.41205
MCM3 minichromosome maintenance complex component 3 3.3561
FZD1 frizzled class receptor 1 3.33418
BDH1 3-hydroxybutyrate dehydrogenase, type 1 3.3276
CHN1 chimerin 1 3.2813
SYNGR3 synaptogyrin 3 3.24795
TATDN2 TatD DNase domain containing 2 3.2476
ATG3 autophagy related 3 3.21425
SELPLG selectin P ligand 3.20708
HDGFL3 HDGF like 3 3.18787
NUCB2 nucleobindin 2 3.1662
MYLK myosin light chain kinase 3.07105
HMOX1 heme oxygenase 1 3.0431
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 3.03315
HEG1 heart development protein with EGF-like domains 1 3.02435
TRAT1 T cell receptor associated transmembrane adaptor 1 3.02255
STAT5B signal transducer and activator of transcription 5B 3.01173
DMAC2L distal membrane arm assembly component 2 like 2.94378
ITM2A integral membrane protein 2A 2.93703
RECK reversion-inducing-cysteine-rich protein with kazal motifs 2.93485
TRAM2 translocation associated membrane protein 2 2.93255
NSG2 neuronal vesicle trafficking associated 2 2.91815
RAB3B RAB3B, member RAS oncogene family 2.91427
VGLL3 vestigial-like family member 3 2.89475
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 2.8441
EGF epidermal growth factor 2.83365
RBPMS RNA binding protein with multiple splicing 2.80657
RALB v-ral simian leukemia viral oncogene homolog B 2.8013
PLPP1 phospholipid phosphatase 1 2.77182
AK5 adenylate kinase 5 2.75745
LOX lysyl oxidase 2.75668
E2F2 E2F transcription factor 2 2.75535
LIN28A lin-28 homolog A (C. elegans) 2.74095
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.7407
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.74025
CSN1S1 casein alpha s1 2.7344
CD47 CD47 molecule 2.71632
GHR growth hormone receptor 2.7044
EVL Enah/Vasp-like 2.6789
ACOT9 acyl-CoA thioesterase 9 2.6728
EPHB2 EPH receptor B2 2.66825
PTPRM protein tyrosine phosphatase, receptor type, M 2.646
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.6235
VNN1 vanin 1 2.61315
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 2.6106
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 2.6097
STK32B serine/threonine kinase 32B 2.59435
WIPF1 WAS/WASL interacting protein family, member 1 2.59262
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 2.58585
FOXJ3 forkhead box J3 2.57337
DKK3 dickkopf WNT signaling pathway inhibitor 3 2.5713
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 2.5672
MAN2B2 mannosidase, alpha, class 2B, member 2 2.56455
GGTLC1 gamma-glutamyltransferase light chain 1 2.56335
POLR1B polymerase (RNA) I polypeptide B, 128kDa 2.56012
PDGFRB platelet-derived growth factor receptor, beta polypeptide 2.5573
SCRN1 secernin 1 2.54795
CASS4 Cas scaffolding protein family member 4 2.54585
EPHB6 EPH receptor B6 2.5398
EFCAB14 EF-hand calcium binding domain 14 2.53408
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 2.5338
GPR171 G protein-coupled receptor 171 2.5234
NOSIP nitric oxide synthase interacting protein 2.5133
TMEM39B transmembrane protein 39B 2.4895
FCHO1 FCH domain only 1 2.48075
SORBS3 sorbin and SH3 domain containing 3 2.47125
TXNDC15 thioredoxin domain containing 15 2.46725
UBASH3A ubiquitin associated and SH3 domain containing A 2.462
IL37 interleukin 37 2.46175
CCNF cyclin F 2.45417
SPATA31C1 SPATA31 subfamily C, member 1 2.4465
CD96 CD96 molecule 2.43035
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 2.41815
SMYD3 SET and MYND domain containing 3 2.41355
SLC35F6 solute carrier family 35, member F6 2.4113
TG thyroglobulin 2.4071
CCNA1 cyclin A1 2.4061
TRIM6-TRIM34 TRIM6-TRIM34 readthrough 2.39765
CYTIP cytohesin 1 interacting protein 2.391
DNTT DNA nucleotidylexotransferase 2.3907
NQO1 NAD(P)H dehydrogenase, quinone 1 2.38818
DOCK10 dedicator of cytokinesis 10 2.38718
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 2.3844
THRAP3 thyroid hormone receptor associated protein 3 2.3788
BHLHE40 basic helix-loop-helix family, member e40 2.3776
TESPA1 thymocyte expressed, positive selection associated 1 2.3716
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 2.3658
BAMBI BMP and activin membrane-bound inhibitor 2.3643
CD69 CD69 molecule 2.36125
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 2.35815
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 2.35385
CMKLR2 chemerin chemokine-like receptor 2 2.35205
LOC124907090 ankyrin repeat domain-containing protein SOWAHC-like 2.3498
KAT7 K(lysine) acetyltransferase 7 2.3364
PTPN21 protein tyrosine phosphatase, non-receptor type 21 2.33048
KEAP1 kelch-like ECH-associated protein 1 2.3262
MINAR1 membrane integral NOTCH2 associated receptor 1 2.3252
CETP cholesteryl ester transfer protein, plasma 2.31915
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 2.3155
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.3128
ANGPT1 angiopoietin 1 2.3091
VGLL4 vestigial-like family member 4 2.2968
NTSR2 neurotensin receptor 2 2.2839
MALT1 MALT1 paracaspase 2.27818
MSMB microseminoprotein, beta- 2.2778
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.27513
FMO1 flavin containing monooxygenase 1 2.27275
H2BC15 H2B clustered histone 15 2.25845
TSPYL1 TSPY-like 1 2.2544
OXSR1 oxidative stress responsive 1 2.24655
GUSB glucuronidase, beta 2.2459
SKAP1 src kinase associated phosphoprotein 1 2.2456
METTL9 methyltransferase like 9 2.24455
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 2.2417
LY6E lymphocyte antigen 6 complex, locus E 2.24155
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 2.23945
OR2H1 olfactory receptor, family 2, subfamily H, member 1 2.22015
SH3YL1 SH3 and SYLF domain containing 1 2.21845
FBXL7 F-box and leucine-rich repeat protein 7 2.2154
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 2.21505
PRB4 proline-rich protein BstNI subfamily 4 2.21305
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled 2.2128
PLK3 polo-like kinase 3 2.2101
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 2.2037
NECTIN3 nectin cell adhesion molecule 3 2.2036
SH3D19 SH3 domain containing 19 2.20302
COL14A1 collagen, type XIV, alpha 1 2.17822
CTAGE8 CTAGE family, member 8 2.17727
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 2.1748
GDF3 growth differentiation factor 3 2.1745
ERBIN erbb2 interacting protein 2.1636
KLRC4 killer cell lectin-like receptor subfamily C, member 4 2.1524
MAT2B methionine adenosyltransferase II, beta 2.1467
TMEM106B transmembrane protein 106B 2.14385
HAVCR1 hepatitis A virus cellular receptor 1 2.14185
ADGRE5 adhesion G protein-coupled receptor E5 2.1389
HNF1B HNF1 homeobox B 2.13725
PIWIL1 piwi-like RNA-mediated gene silencing 1 2.13615
TSHR thyroid stimulating hormone receptor 2.13557
AGO1 argonaute RISC catalytic component 1 2.13485
NID2 nidogen 2 (osteonidogen) 2.13065
GSTK1 glutathione S-transferase kappa 1 2.12745
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 2.12672
KIF21B kinesin family member 21B 2.12625
CCDC85B coiled-coil domain containing 85B 2.12475
GAK cyclin G associated kinase 2.12472
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 2.11785
IQGAP2 IQ motif containing GTPase activating protein 2 2.117
SP140 SP140 nuclear body protein 2.11665
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.1088
CXCL12 chemokine (C-X-C motif) ligand 12 2.1073
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 2.1062
PHACTR4 phosphatase and actin regulator 4 2.1048
LOXL1 lysyl oxidase-like 1 2.10305
ACVR1 activin A receptor, type I 2.1029
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 2.10255
SQSTM1 sequestosome 1 2.10225
FBN1 fibrillin 1 2.09263
LRRTM2 leucine rich repeat transmembrane neuronal 2 2.08995
PCOLCE procollagen C-endopeptidase enhancer 2.0898
UTRN utrophin 2.08862
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 2.0883
COL6A3 collagen, type VI, alpha 3 2.08825
MAGEL2 melanoma antigen family L2 2.0882
KYAT3 kynurenine aminotransferase 3 2.088
BRDT bromodomain, testis-specific 2.08775
GET1 guided entry of tail-anchored proteins factor 1 2.0833
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 2.0765
DPPA4 developmental pluripotency associated 4 2.0763
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 2.0756
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 2.07505
PDCD6IP programmed cell death 6 interacting protein 2.07325
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 2.0731
LPGAT1 lysophosphatidylglycerol acyltransferase 1 2.0703
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 2.07005
PLA2G2F phospholipase A2, group IIF 2.06915
PRDX4 peroxiredoxin 4 2.06415
NANOG Nanog homeobox 2.0634
CDC45 cell division cycle 45 2.0601
CNTN1 contactin 1 2.0578
FAT4 FAT atypical cadherin 4 2.05205
BDNF brain-derived neurotrophic factor 2.05175
CUBN cubilin (intrinsic factor-cobalamin receptor) 2.04195
EDN1 endothelin 1 2.0403
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 2.0369
ETV6 ets variant 6 2.0344
WNT5B wingless-type MMTV integration site family, member 5B 2.0335
SIRT3 sirtuin 3 2.03323
FOXO3 forkhead box O3 2.03202
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.02995
ADAM29 ADAM metallopeptidase domain 29 2.02995
CZIB CXXC motif containing zinc binding protein 2.0287
AGTR1 angiotensin II receptor, type 1 2.02688
TMPRSS3 transmembrane protease, serine 3 2.02595
TRAK2 trafficking protein, kinesin binding 2 2.02548
SFTPB surfactant protein B 2.02507
TP53I3 tumor protein p53 inducible protein 3 2.0243
SYT1 synaptotagmin I 2.0196
IFNG interferon, gamma 2.0182
BEX4 brain expressed, X-linked 4 2.0127
AANAT aralkylamine N-acetyltransferase 2.00975
POU5F1 POU class 5 homeobox 1 2.00929
EHMT1 euchromatic histone-lysine N-methyltransferase 1 2.0086
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 2.0075
GLT8D2 glycosyltransferase 8 domain containing 2 2.00695
PPP1R17 protein phosphatase 1, regulatory subunit 17 2.00045

decreased expression

Symbol Name Standardized Value
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -10.0
CAB39 calcium binding protein 39 -9.29435
TCTN1 tectonic family member 1 -8.9407
ZDHHC6 zinc finger, DHHC-type containing 6 -7.2649
ISOC1 isochorismatase domain containing 1 -6.12045
SLC35F2 solute carrier family 35, member F2 -5.75595
TRIB3 tribbles pseudokinase 3 -5.6668
FASTKD5 FAST kinase domains 5 -5.23825
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -5.2265
PGM1 phosphoglucomutase 1 -5.1434
RGS2 regulator of G-protein signaling 2 -5.07425
BIRC2 baculoviral IAP repeat containing 2 -4.97455
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -4.83315
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -4.7469
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -4.66025
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.6169
RFC2 replication factor C (activator 1) 2, 40kDa -4.3934
FAIM Fas apoptotic inhibitory molecule -4.3805
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -4.36375
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -4.3444
FBXL12 F-box and leucine-rich repeat protein 12 -4.3031
ANKRD10 ankyrin repeat domain 10 -4.2663
LOC124907782 dual specificity protein phosphatase 22 -4.20345
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -4.18488
CIAPIN1 cytokine induced apoptosis inhibitor 1 -4.17968
SCAND1 SCAN domain containing 1 -4.0844
GNAS GNAS complex locus -4.01201
SPAG4 sperm associated antigen 4 -3.96985
MYL9 myosin, light chain 9, regulatory -3.96275
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha -3.82115
TLCD3A TLC domain containing 3A -3.7941
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.7429
TXNDC9 thioredoxin domain containing 9 -3.67057
NGRN neugrin, neurite outgrowth associated -3.64115
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -3.6344
ERBB2 erb-b2 receptor tyrosine kinase 2 -3.5687
OXA1L oxidase (cytochrome c) assembly 1-like -3.54615
DENND2D DENN/MADD domain containing 2D -3.42345
RHOA ras homolog family member A -3.4063
CRTAP cartilage associated protein -3.3966
TOGARAM1 TOG array regulator of axonemal microtubules 1 -3.37405
NSDHL NAD(P) dependent steroid dehydrogenase-like -3.27005
GFOD1 glucose-fructose oxidoreductase domain containing 1 -3.2665
GRB7 growth factor receptor-bound protein 7 -3.2233
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -3.2151
NUDC nudC nuclear distribution protein -3.18288
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -3.1353
PSRC1 proline/serine-rich coiled-coil 1 -3.1185
NRIP1 nuclear receptor interacting protein 1 -3.10922
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -3.09425
CHIC2 cysteine-rich hydrophobic domain 2 -3.0938
THOP1 thimet oligopeptidase 1 -3.06325
ASDURF ASNSD1 upstream open reading frame -3.04515
SHOC2 soc-2 suppressor of clear homolog (C. elegans) -2.9979
ZNF473 zinc finger protein 473 -2.9723
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -2.9659
SNIP1 Smad nuclear interacting protein 1 -2.9214
XPO7 exportin 7 -2.87037
TOR1A torsin family 1, member A (torsin A) -2.82693
CRELD2 cysteine-rich with EGF-like domains 2 -2.81105
IRGQ immunity-related GTPase family, Q -2.8092
HMG20B high mobility group 20B -2.7852
S100A2 S100 calcium binding protein A2 -2.7792
S100A3 S100 calcium binding protein A3 -2.76435
MRPL4 mitochondrial ribosomal protein L4 -2.75525
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.7452
TBP TATA box binding protein -2.74295
ABHD6 abhydrolase domain containing 6 -2.73983
E2F5 E2F transcription factor 5, p130-binding -2.73945
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) -2.71217
RPL35 ribosomal protein L35 -2.7059
CENPE centromere protein E, 312kDa -2.69955
MICALL1 MICAL-like 1 -2.679
NENF neudesin neurotrophic factor -2.67765
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -2.67625
FGFBP1 fibroblast growth factor binding protein 1 -2.67
PLAT plasminogen activator, tissue -2.6626
TBC1D10C TBC1 domain family, member 10C -2.65925
WHR1 winged helix repair factor 1 -2.65775
PRPF4 pre-mRNA processing factor 4 -2.63928
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 -2.638
DCK deoxycytidine kinase -2.6324
MTPAP mitochondrial poly(A) polymerase -2.6282
FBXO3 F-box protein 3 -2.6203
HOXA5 homeobox A5 -2.62025
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -2.5882
PWWP3A PWWP domain containing 3A, DNA repair factor -2.57565
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -2.57095
LIN37 lin-37 DREAM MuvB core complex component -2.5693
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.56665
EOLA1 endothelium and lymphocyte associated ASCH domain 1 -2.56278
HYOU1 hypoxia up-regulated 1 -2.55385
PHKG2 phosphorylase kinase, gamma 2 (testis) -2.54555
TMEM176B transmembrane protein 176B -2.54545
HAT1 histone acetyltransferase 1 -2.53515
ZNF586 zinc finger protein 586 -2.53405
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -2.517
RBX1 ring-box 1, E3 ubiquitin protein ligase -2.5157
MTA1 metastasis associated 1 -2.50867
DNAAF5 dynein, axonemal, assembly factor 5 -2.5084
COX6C cytochrome c oxidase subunit VIc -2.5048
EMC6 ER membrane protein complex subunit 6 -2.50205
MIS12 MIS12 kinetochore complex component -2.49835
S100A8 S100 calcium binding protein A8 -2.4778
IKZF5 IKAROS family zinc finger 5 (Pegasus) -2.47275
PDGFA platelet-derived growth factor alpha polypeptide -2.46838
RPL23A ribosomal protein L23a -2.46269
EEF2 eukaryotic translation elongation factor 2 -2.45827
HLA-B major histocompatibility complex, class I, B -2.45602
ZNF232 zinc finger protein 232 -2.45565
SLC66A2 solute carrier family 66 member 2 -2.4431
EGR1 early growth response 1 -2.43195
GAA glucosidase, alpha; acid -2.4311
ERH enhancer of rudimentary homolog (Drosophila) -2.43
RPS29 ribosomal protein S29 -2.4011
ANKRD46 ankyrin repeat domain 46 -2.3944
CASP7 caspase 7, apoptosis-related cysteine peptidase -2.38875
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -2.38435
MANF mesencephalic astrocyte-derived neurotrophic factor -2.3805
CLDN6 claudin 6 -2.37895
TUSC2 tumor suppressor candidate 2 -2.3732
ZFAND3 zinc finger, AN1-type domain 3 -2.36345
ISOC2 isochorismatase domain containing 2 -2.35995
CTNND1 catenin (cadherin-associated protein), delta 1 -2.35788
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -2.3519
ADNP2 ADNP homeobox 2 -2.3503
RPS23 ribosomal protein S23 -2.34405
EMD emerin -2.3407
TDG thymine-DNA glycosylase -2.3343
NUP85 nucleoporin 85kDa -2.331
HMGA2 high mobility group AT-hook 2 -2.33
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -2.3282
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.3256
RPL9 ribosomal protein L9 -2.32535
RPS18 ribosomal protein S18 -2.32485
RPL41 ribosomal protein L41 -2.32365
RUBCNL rubicon like autophagy enhancer -2.31943
ITGB1BP1 integrin beta 1 binding protein 1 -2.3121
AAR2 AAR2 splicing factor homolog (S. cerevisiae) -2.30965
PUM3 pumilio RNA binding family member 3 -2.3084
VAMP8 vesicle-associated membrane protein 8 -2.30805
CCDC92 coiled-coil domain containing 92 -2.29935
MKNK1 MAP kinase interacting serine/threonine kinase 1 -2.29705
MECR mitochondrial trans-2-enoyl-CoA reductase -2.2967
MMP10 matrix metallopeptidase 10 -2.2954
MCUR1 mitochondrial calcium uniporter regulator 1 -2.2934
RPL39 ribosomal protein L39 -2.2933
RPL7A ribosomal protein L7a -2.2924
SYNGR2 synaptogyrin 2 -2.2843
RPS13 ribosomal protein S13 -2.2778
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) -2.27398
PYDC1 PYD (pyrin domain) containing 1 -2.27355
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 -2.25948
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -2.2565
ZFAND1 zinc finger, AN1-type domain 1 -2.252
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 -2.2518
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa -2.2512
RPS15A ribosomal protein S15a -2.2475
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.24465
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.23578
ZNF7 zinc finger protein 7 -2.23385
HTD2 hydroxyacyl-thioester dehydratase type 2 -2.23305
RPUSD2 RNA pseudouridylate synthase domain containing 2 -2.23305
ABRAXAS2 abraxas 2, BRISC complex subunit -2.23282
MIURF mitochondrial elongation factor 1 upstream open reading frame -2.23202
OSER1 oxidative stress responsive serine-rich 1 -2.23075
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 -2.22615
RPS10 ribosomal protein S10 -2.2255
CIAO2B cytosolic iron-sulfur assembly component 2B -2.2182
OXR1 oxidation resistance 1 -2.20735
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -2.20333
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 -2.20325
UBAC1 UBA domain containing 1 -2.1999
LITAF lipopolysaccharide-induced TNF factor -2.19637
CDKN2A cyclin-dependent kinase inhibitor 2A -2.19405
TMEM231 transmembrane protein 231 -2.1906
PTPRE protein tyrosine phosphatase, receptor type, E -2.1841
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -2.18138
ZNF184 zinc finger protein 184 -2.1775
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.172
NPM3 nucleophosmin/nucleoplasmin 3 -2.1717
DKC1 dyskeratosis congenita 1, dyskerin -2.1716
STOML2 stomatin (EPB72)-like 2 -2.167
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa -2.16325
ZNF629 zinc finger protein 629 -2.16005
COL9A2 collagen, type IX, alpha 2 -2.1545
SLC39A7 solute carrier family 39 (zinc transporter), member 7 -2.15365
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -2.1518
WDR37 WD repeat domain 37 -2.1451
MINPP1 multiple inositol-polyphosphate phosphatase 1 -2.14445
KRT6B keratin 6B, type II -2.14325
RING1 ring finger protein 1 -2.14232
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) -2.1406
IFT20 intraflagellar transport 20 -2.13675
H2AB2 H2A.B variant histone 2 -2.13505
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial -2.13215
BARX1 BARX homeobox 1 -2.12415
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -2.1213
CCDC59 coiled-coil domain containing 59 -2.12125
MED17 mediator complex subunit 17 -2.11865
UBL5 ubiquitin-like 5 -2.11745
PDZD8 PDZ domain containing 8 -2.1138
PGAP3 post-GPI attachment to proteins 3 -2.11203
PRRC2A proline-rich coiled-coil 2A -2.11098
CDC40 cell division cycle 40 -2.10987
GEMIN6 gem (nuclear organelle) associated protein 6 -2.1018
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 -2.10055
AHCTF1 AT hook containing transcription factor 1 -2.0958
ARID5B AT rich interactive domain 5B (MRF1-like) -2.09145
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -2.09118
PDZD2 PDZ domain containing 2 -2.0891
RPS4X ribosomal protein S4, X-linked -2.08725
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C -2.084
ING1 inhibitor of growth family, member 1 -2.08245
SUSD6 sushi domain containing 6 -2.0814
CSNK1G3 casein kinase 1, gamma 3 -2.08105
TGDS TDP-glucose 4,6-dehydratase -2.07935
ZNF706 zinc finger protein 706 -2.0741
NHLRC2 NHL repeat containing 2 -2.0717
MIA melanoma inhibitory activity -2.0653
IRF2BP1 interferon regulatory factor 2 binding protein 1 -2.05755
PRAF2 PRA1 domain family, member 2 -2.05715
RPL32 ribosomal protein L32 -2.0541
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.05365
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 -2.05325
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -2.0511
MAK16 MAK16 homolog (S. cerevisiae) -2.0476
BRIX1 BRX1, biogenesis of ribosomes -2.04315
THAP1 THAP domain containing, apoptosis associated protein 1 -2.0388
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.0381
ANXA8L1 annexin A8-like 1 -2.03485
LARP4 La ribonucleoprotein domain family, member 4 -2.0309
DSN1 DSN1, MIS12 kinetochore complex component -2.0284
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 -2.0269
ZBTB10 zinc finger and BTB domain containing 10 -2.02515
NKRF NFKB repressing factor -2.0164
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 -2.01575
BIRC5 baculoviral IAP repeat containing 5 -2.01135
RPS17 ribosomal protein S17 -2.01128
KRT5 keratin 5, type II -2.01075
HLA-A major histocompatibility complex, class I, A -2.00568
NOP16 NOP16 nucleolar protein -2.00553
COL11A2 collagen, type XI, alpha 2 -2.00175