| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | potassium 1h-indol-3-yl sulfate 2.71 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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84 genes differentially expressed following the CRCGN009_HEPG2_24H:F04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPER1 | G protein-coupled estrogen receptor 1 | 6.56772 |
| MVP | major vault protein | 5.33609 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.90929 |
| CNPY3 | canopy FGF signaling regulator 3 | 4.89954 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.57827 |
| TXNRD1 | thioredoxin reductase 1 | 4.43321 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 4.32619 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.12301 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.06484 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.86338 |
| IDE | insulin-degrading enzyme | 3.29505 |
| CHMP6 | charged multivesicular body protein 6 | 3.09554 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 3.06201 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 3.03988 |
| GHR | growth hormone receptor | 2.98287 |
| LSR | lipolysis stimulated lipoprotein receptor | 2.971 |
| MCM3 | minichromosome maintenance complex component 3 | 2.91527 |
| LCN2 | lipocalin 2 | 2.91497 |
| TATDN2 | TatD DNase domain containing 2 | 2.76986 |
| EPHA3 | EPH receptor A3 | 2.75318 |
| SQOR | sulfide quinone oxidoreductase | 2.72095 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 2.71994 |
| RAP1GAP | RAP1 GTPase activating protein | 2.68591 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.64718 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.63214 |
| PRR15L | proline rich 15-like | 2.45002 |
| TSPAN6 | tetraspanin 6 | 2.4473 |
| FCHO1 | FCH domain only 1 | 2.4247 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | 2.38837 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 2.38056 |
| STX4 | syntaxin 4 | 2.35359 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 2.35133 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.31091 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.30378 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 2.27729 |
| CRYZ | crystallin, zeta (quinone reductase) | 2.25478 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.23945 |
| BMP4 | bone morphogenetic protein 4 | 2.17004 |
| CYTH1 | cytohesin 1 | 2.10252 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 2.08673 |
| FBXW4 | F-box and WD repeat domain containing 4 | 2.08519 |
| NOSIP | nitric oxide synthase interacting protein | 2.07213 |
| EVL | Enah/Vasp-like | 2.06282 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.05561 |
| PRKCD | protein kinase C, delta | 2.04955 |
| DPP4 | dipeptidyl-peptidase 4 | 2.02292 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -7.16904 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.87455 |
| SLC35F2 | solute carrier family 35, member F2 | -5.73294 |
| TCTN1 | tectonic family member 1 | -5.22451 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.74823 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -4.2054 |
| VAT1 | vesicle amine transport 1 | -4.08523 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.84263 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -3.67273 |
| PRPF4 | pre-mRNA processing factor 4 | -3.56124 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.34808 |
| LDHD | lactate dehydrogenase D | -3.29033 |
| CD320 | CD320 molecule | -3.26591 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | -3.25108 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.23947 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.20959 |
| ZNF586 | zinc finger protein 586 | -3.20666 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.16349 |
| CCDC86 | coiled-coil domain containing 86 | -3.0937 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.07972 |
| TLR4 | toll-like receptor 4 | -3.00296 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.82542 |
| CCNB1 | cyclin B1 | -2.74951 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -2.72565 |
| SPAG4 | sperm associated antigen 4 | -2.64514 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -2.54269 |
| TCERG1 | transcription elongation regulator 1 | -2.50566 |
| CDK1 | cyclin-dependent kinase 1 | -2.37983 |
| GNAS | GNAS complex locus | -2.34782 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -2.33656 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.33189 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.30168 |
| ALDOC | aldolase C, fructose-bisphosphate | -2.22149 |
| HEATR1 | HEAT repeat containing 1 | -2.17327 |
| FASTKD5 | FAST kinase domains 5 | -2.15168 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.11892 |
| RHOH | ras homolog family member H | -2.04475 |
| ACTMAP | actin maturation protease | -2.00942 |
