| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | potassium 1h-indol-3-yl sulfate 0.68 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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54 genes differentially expressed following the CRCGN009_HEPG2_24H:F06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GSTZ1 | glutathione S-transferase zeta 1 | 5.45136 |
| MAP7 | microtubule-associated protein 7 | 5.18391 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.17911 |
| ATP11B | ATPase, class VI, type 11B | 4.72519 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.34826 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.92447 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 3.89469 |
| VAT1 | vesicle amine transport 1 | 3.79254 |
| MVP | major vault protein | 3.6044 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 3.59807 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 3.48708 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.33518 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.99424 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.87496 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 2.83413 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.58749 |
| CYCS | cytochrome c, somatic | 2.55266 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 2.54092 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.50458 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.49583 |
| HMGN1 | high mobility group nucleosome binding domain 1 | 2.48577 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 2.45456 |
| STK10 | serine/threonine kinase 10 | 2.45071 |
| STAP2 | signal transducing adaptor family member 2 | 2.37589 |
| HMOX1 | heme oxygenase 1 | 2.35211 |
| GATA3 | GATA binding protein 3 | 2.31616 |
| EGF | epidermal growth factor | 2.28616 |
| ABHD6 | abhydrolase domain containing 6 | 2.26915 |
| ATG3 | autophagy related 3 | 2.24973 |
| TXNRD1 | thioredoxin reductase 1 | 2.12075 |
| SLC75A1 | solute carrier family 75 member 1 | 2.07346 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.00029 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -6.52131 |
| ADI1 | acireductone dioxygenase 1 | -6.41543 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.12635 |
| THAP11 | THAP domain containing 11 | -4.42649 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -3.92116 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.82042 |
| SMNDC1 | survival motor neuron domain containing 1 | -3.46028 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.33299 |
| TLCD3A | TLC domain containing 3A | -3.27386 |
| CCNB2 | cyclin B2 | -3.14556 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.10952 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.80928 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.69713 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -2.69673 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.5567 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.52177 |
| DSG2 | desmoglein 2 | -2.51689 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.50899 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -2.45821 |
| EXT1 | exostosin glycosyltransferase 1 | -2.30015 |
| RGS2 | regulator of G-protein signaling 2 | -2.24547 |
| ZNF586 | zinc finger protein 586 | -2.13419 |
