CRCGN009_HEPG2_24H:F07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

85 genes differentially expressed following the CRCGN009_HEPG2_24H:F07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 7.84143
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 7.82977
SNAP25 synaptosomal-associated protein, 25kDa 7.32665
MAP7 microtubule-associated protein 7 5.55296
PEX11A peroxisomal biogenesis factor 11 alpha 4.51919
CHMP6 charged multivesicular body protein 6 4.30832
LPAR2 lysophosphatidic acid receptor 2 4.12317
STK10 serine/threonine kinase 10 4.02735
RPL39L ribosomal protein L39-like 3.90742
BACE2 beta-site APP-cleaving enzyme 2 3.72448
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 3.56484
MYLK myosin light chain kinase 3.48154
ABHD6 abhydrolase domain containing 6 3.46595
TIAM1 T-cell lymphoma invasion and metastasis 1 3.45581
MEF2C myocyte enhancer factor 2C 3.34907
EPN2 epsin 2 3.24291
STIMATE STIM activating enhancer 3.09688
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.99521
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.97484
CHEK2 checkpoint kinase 2 2.87893
SNCB synuclein, beta 2.83272
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.80967
JADE2 jade family PHD finger 2 2.77486
NENF neudesin neurotrophic factor 2.7252
SYN1 synapsin I 2.68302
TBPL1 TBP-like 1 2.67982
NUP133 nucleoporin 133kDa 2.53673
PPARG peroxisome proliferator-activated receptor gamma 2.50581
CCNF cyclin F 2.48603
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.45547
CNTN1 contactin 1 2.42833
LSR lipolysis stimulated lipoprotein receptor 2.3513
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.34807
PNKP polynucleotide kinase 3'-phosphatase 2.33987
MYL1 myosin, light chain 1, alkali; skeletal, fast 2.29153
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 2.26714
MCUR1 mitochondrial calcium uniporter regulator 1 2.23438
GSTZ1 glutathione S-transferase zeta 1 2.22565
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 2.21932
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.21008
ASIC2 acid sensing (proton gated) ion channel 2 2.18455
CDK4 cyclin-dependent kinase 4 2.15265
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 2.1471
ACTA1 actin, alpha 1, skeletal muscle 2.14549
NSG2 neuronal vesicle trafficking associated 2 2.12418
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 2.12092
TUBB4A tubulin, beta 4A class IVa 2.09016
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.07017
GNG12 guanine nucleotide binding protein (G protein), gamma 12 2.06245
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 2.03386

decreased expression

Symbol Name Standardized Value
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -7.80358
GNAS GNAS complex locus -7.48887
DHRS7 dehydrogenase/reductase (SDR family) member 7 -7.42117
OXA1L oxidase (cytochrome c) assembly 1-like -6.38175
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -4.53646
TSEN2 TSEN2 tRNA splicing endonuclease subunit -4.49605
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -4.38368
CDC20 cell division cycle 20 -4.34734
CASP7 caspase 7, apoptosis-related cysteine peptidase -4.19326
GOLT1B golgi transport 1B -4.04072
ISOC1 isochorismatase domain containing 1 -4.02354
ERBB2 erb-b2 receptor tyrosine kinase 2 -3.67501
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.5463
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.04978
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.97131
CSK c-src tyrosine kinase -2.93296
TLCD3A TLC domain containing 3A -2.93249
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.66619
NRIP1 nuclear receptor interacting protein 1 -2.63986
GPR88 G protein-coupled receptor 88 -2.47128
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.44075
RNF130 ring finger protein 130 -2.41313
ATP5F1D ATP synthase F1 subunit delta -2.34861
SF3A3 splicing factor 3a, subunit 3, 60kDa -2.32025
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 -2.30677
SRPRA SRP receptor subunit alpha -2.24958
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -2.17178
CS citrate synthase -2.12
SLC35F2 solute carrier family 35, member F2 -2.11296
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -2.09485
ARCN1 archain 1 -2.09256
CHEK1 checkpoint kinase 1 -2.04879
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -2.02192
PEG10 paternally expressed 10 -2.00998
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -2.00974