| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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83 genes differentially expressed following the CRCGN009_HEPG2_24H:F08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYLK | myosin light chain kinase | 8.78258 |
| CBR3 | carbonyl reductase 3 | 5.9931 |
| ADRB2 | adrenoceptor beta 2, surface | 5.75927 |
| MOK | MOK protein kinase | 5.39142 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 5.21511 |
| E2F2 | E2F transcription factor 2 | 4.99909 |
| LCN2 | lipocalin 2 | 4.975 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.88168 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.81314 |
| EPHB2 | EPH receptor B2 | 4.72128 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.3242 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.84615 |
| ZFP36 | ZFP36 ring finger protein | 3.77654 |
| PLSCR1 | phospholipid scramblase 1 | 3.63355 |
| MTERF3 | mitochondrial transcription termination factor 3 | 3.56264 |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | 3.51225 |
| NOTCH1 | notch 1 | 3.4492 |
| KLHL9 | kelch-like family member 9 | 3.43044 |
| RXYLT1 | ribitol xylosyltransferase 1 | 3.29197 |
| EVL | Enah/Vasp-like | 3.04408 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 2.87225 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.83144 |
| LOC122526780 | uncharacterized LOC122526780 | 2.61814 |
| E2F5 | E2F transcription factor 5, p130-binding | 2.58018 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.52994 |
| DIPK1A | divergent protein kinase domain 1A | 2.50736 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.37924 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.37142 |
| NANOS3 | nanos homolog 3 (Drosophila) | 2.34925 |
| RAB21 | RAB21, member RAS oncogene family | 2.34005 |
| PRR15L | proline rich 15-like | 2.2896 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.2888 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 | 2.26823 |
| TAC4 | tachykinin 4 (hemokinin) | 2.26257 |
| TCTA | T-cell leukemia translocation altered | 2.24067 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.21592 |
| COPS7A | COP9 signalosome subunit 7A | 2.17195 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | 2.12225 |
| SDC3 | syndecan 3 | 2.0992 |
| TSPAN6 | tetraspanin 6 | 2.07307 |
| SHB | Src homology 2 domain containing adaptor protein B | 2.06599 |
| LCN1 | lipocalin 1 | 2.05452 |
| EPHB3 | EPH receptor B3 | 2.04097 |
| ZFC3H1 | zinc finger, C3H1-type containing | 2.03759 |
| ZNHIT6 | zinc finger, HIT-type containing 6 | 2.02826 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.02518 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -10.0 |
| CCNB2 | cyclin B2 | -7.90221 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -4.98659 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.79041 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.71339 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.69247 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.67136 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.74695 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.70875 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.70546 |
| PRPF4 | pre-mRNA processing factor 4 | -3.54551 |
| EGF | epidermal growth factor | -3.47301 |
| LDHD | lactate dehydrogenase D | -3.45598 |
| SLC35F2 | solute carrier family 35, member F2 | -3.30656 |
| TLR4 | toll-like receptor 4 | -3.28516 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -3.15048 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.10226 |
| GNAS | GNAS complex locus | -3.05033 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -3.04257 |
| YME1L1 | YME1-like 1 ATPase | -2.98517 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.96622 |
| ICAM3 | intercellular adhesion molecule 3 | -2.66088 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.55472 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.49479 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.43041 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.35979 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -2.26562 |
| PAX6 | paired box 6 | -2.24619 |
| SLC4A1AP | solute carrier family 4 (anion exchanger), member 1, adaptor protein | -2.20513 |
| SLC2A14 | solute carrier family 2 (facilitated glucose transporter), member 14 | -2.20472 |
| RGS2 | regulator of G-protein signaling 2 | -2.18183 |
| PDZD2 | PDZ domain containing 2 | -2.17712 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.17476 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | -2.08362 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -2.07161 |
| USP6NL | USP6 N-terminal like | -2.06869 |
| NVL | nuclear VCP-like | -2.03893 |
