CRCGN009_HEPG2_24H:F09 Gene Set
Genes
59 genes differentially expressed following the CRCGN009_HEPG2_24H:F09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
6.91089
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
4.39462
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.02264
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.88899
|
|
E2F2
|
E2F transcription factor 2
|
3.88857
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
3.8103
|
|
EVL
|
Enah/Vasp-like
|
3.40443
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
3.32905
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.19343
|
|
HDGFL3
|
HDGF like 3
|
3.15511
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
3.12097
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.06466
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.90816
|
|
EPN2
|
epsin 2
|
2.86539
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.85652
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.82752
|
|
KIF5C
|
kinesin family member 5C
|
2.81295
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.74472
|
|
STK10
|
serine/threonine kinase 10
|
2.62266
|
|
CRTAP
|
cartilage associated protein
|
2.61653
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.51762
|
|
ADGRL3
|
adhesion G protein-coupled receptor L3
|
2.42837
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.41691
|
|
PMM2
|
phosphomannomutase 2
|
2.33083
|
|
SATB1
|
SATB homeobox 1
|
2.2625
|
|
PFKL
|
phosphofructokinase, liver
|
2.19485
|
|
CCNF
|
cyclin F
|
2.18503
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.08749
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
2.02984
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.9468
|
|
CDC20
|
cell division cycle 20
|
-6.88633
|
|
ZNF586
|
zinc finger protein 586
|
-6.86848
|
|
PCNA
|
proliferating cell nuclear antigen
|
-6.77597
|
|
CCNB2
|
cyclin B2
|
-5.92412
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.71635
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.55508
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-4.14886
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.70159
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-3.68773
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-3.56371
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.38376
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.24469
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.03186
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-3.02144
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.73575
|
|
FDFT1
|
farnesyl-diphosphate farnesyltransferase 1
|
-2.39363
|
|
SIDT1
|
SID1 transmembrane family, member 1
|
-2.31971
|
|
GNAS
|
GNAS complex locus
|
-2.30876
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.2927
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.19196
|
|
TMEM248
|
transmembrane protein 248
|
-2.18371
|
|
ELOVL1
|
ELOVL fatty acid elongase 1
|
-2.11741
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.10973
|
|
AIFM2
|
apoptosis-inducing factor, mitochondrion-associated, 2
|
-2.05788
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.03927
|
|
TIMM10B
|
translocase of inner mitochondrial membrane 10 homolog B (yeast)
|
-2.03184
|
|
TRAM1
|
translocation associated membrane protein 1
|
-2.00779
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.0064
|
|
HBE1
|
hemoglobin, epsilon 1
|
-2.0025
|
