CRCGN009_HEPG2_24H:F11 Gene Set
Genes
50 genes differentially expressed following the CRCGN009_HEPG2_24H:F11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
7.87607
|
|
E2F2
|
E2F transcription factor 2
|
4.93055
|
|
MOK
|
MOK protein kinase
|
4.80065
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.72094
|
|
EPHB2
|
EPH receptor B2
|
3.74188
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.33182
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.95871
|
|
STIMATE
|
STIM activating enhancer
|
2.87497
|
|
LCN2
|
lipocalin 2
|
2.83461
|
|
ICAM1
|
intercellular adhesion molecule 1
|
2.70822
|
|
TATDN2
|
TatD DNase domain containing 2
|
2.62888
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.61427
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.54191
|
|
SLC35A3
|
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
|
2.45449
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.41202
|
|
CHN1
|
chimerin 1
|
2.33702
|
|
CHEK2
|
checkpoint kinase 2
|
2.32984
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.24716
|
|
PFKL
|
phosphofructokinase, liver
|
2.19347
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
2.17737
|
|
CYP2J2
|
cytochrome P450, family 2, subfamily J, polypeptide 2
|
2.15415
|
|
PID1
|
phosphotyrosine interaction domain containing 1
|
2.00344
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-7.69001
|
|
LDHD
|
lactate dehydrogenase D
|
-6.89836
|
|
TRIB3
|
tribbles pseudokinase 3
|
-5.33789
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-4.90267
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.82545
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.80616
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.71735
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.52407
|
|
CDC25B
|
cell division cycle 25B
|
-4.45049
|
|
EGF
|
epidermal growth factor
|
-4.22828
|
|
HMG20B
|
high mobility group 20B
|
-4.02918
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-3.59795
|
|
PEG10
|
paternally expressed 10
|
-3.56295
|
|
NISCH
|
nischarin
|
-3.48169
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-3.33102
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.30602
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-3.29611
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.10836
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.01914
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.93433
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.82836
|
|
TLR4
|
toll-like receptor 4
|
-2.5654
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.52167
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.39085
|
|
KRT14
|
keratin 14, type I
|
-2.06165
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.04174
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.03736
|
|
CDKN2AIP
|
CDKN2A interacting protein
|
-2.02109
|
