CRCGN009_HEPG2_24H:F16 Gene Set
Genes
42 genes differentially expressed following the CRCGN009_HEPG2_24H:F16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
5.28455
|
|
CYCS
|
cytochrome c, somatic
|
5.024
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
4.53716
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.96524
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.58033
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
3.54773
|
|
KLHL9
|
kelch-like family member 9
|
3.39788
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.34475
|
|
ZFP36
|
ZFP36 ring finger protein
|
3.19596
|
|
TBPL1
|
TBP-like 1
|
3.16113
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.15983
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.13616
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.00659
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.9945
|
|
STIMATE
|
STIM activating enhancer
|
2.94953
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.93194
|
|
MOK
|
MOK protein kinase
|
2.77356
|
|
TRAM2
|
translocation associated membrane protein 2
|
2.77048
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.72824
|
|
LCN2
|
lipocalin 2
|
2.63709
|
|
GATA2
|
GATA binding protein 2
|
2.56224
|
|
GADD45A
|
growth arrest and DNA-damage-inducible, alpha
|
2.50823
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.49538
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-6.02612
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-4.54852
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-4.42433
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.34093
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.95017
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.75519
|
|
CDC20
|
cell division cycle 20
|
-3.31652
|
|
DSG2
|
desmoglein 2
|
-3.14478
|
|
CCNB2
|
cyclin B2
|
-2.99241
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.8119
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.56848
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.19444
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.16409
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.16236
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.12054
|
|
ASAH1
|
N-acylsphingosine amidohydrolase (acid ceramidase) 1
|
-2.10059
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.07978
|
|
CAB39
|
calcium binding protein 39
|
-2.07842
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.02203
|
