CRCGN009_HEPG2_24H:F18 Gene Set
Genes
47 genes differentially expressed following the CRCGN009_HEPG2_24H:F18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
7.73774
|
|
PRKCH
|
protein kinase C, eta
|
5.13997
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
5.12059
|
|
LCN2
|
lipocalin 2
|
5.05758
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
5.00818
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
4.97793
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
4.9019
|
|
ATP11B
|
ATPase, class VI, type 11B
|
4.71545
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.52575
|
|
CHN1
|
chimerin 1
|
3.26423
|
|
JADE2
|
jade family PHD finger 2
|
3.1103
|
|
CBR3
|
carbonyl reductase 3
|
2.78912
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.76589
|
|
SEH1L
|
SEH1-like (S. cerevisiae)
|
2.24508
|
|
DCHS2
|
dachsous cadherin-related 2
|
2.22967
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.16198
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.09717
|
|
HAX1
|
HCLS1 associated protein X-1
|
2.0641
|
|
EPHA3
|
EPH receptor A3
|
2.05848
|
|
S100G
|
S100 calcium binding protein G
|
2.05099
|
|
TXK
|
TXK tyrosine kinase
|
2.05008
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.03095
|
|
TBC1D31
|
TBC1 domain family, member 31
|
2.02052
|
|
LCT
|
lactase
|
2.02025
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.00564
|
|
HS2ST1
|
heparan sulfate 2-O-sulfotransferase 1
|
2.0017
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSPB1
|
heat shock 27kDa protein 1
|
-7.53391
|
|
TLR4
|
toll-like receptor 4
|
-5.82436
|
|
CCNB2
|
cyclin B2
|
-5.02695
|
|
LDHD
|
lactate dehydrogenase D
|
-4.85213
|
|
CSK
|
c-src tyrosine kinase
|
-4.82416
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-4.80279
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.68989
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.54636
|
|
ZNF586
|
zinc finger protein 586
|
-4.39386
|
|
EGF
|
epidermal growth factor
|
-3.76223
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.56435
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.32757
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.31212
|
|
ASAH1
|
N-acylsphingosine amidohydrolase (acid ceramidase) 1
|
-2.99339
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.93467
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.92115
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.74592
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.63044
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.58955
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.45979
|
|
CPB1
|
carboxypeptidase B1 (tissue)
|
-2.17634
|
