| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | kepone 4.92 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
62 genes differentially expressed following the CRCGN009_HEPG2_24H:F22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 7.30378 |
| CYCS | cytochrome c, somatic | 5.52633 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 5.0764 |
| MAMLD1 | mastermind-like domain containing 1 | 4.5424 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.24348 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.16632 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 4.15104 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.05008 |
| LCN2 | lipocalin 2 | 3.90572 |
| GPATCH8 | G patch domain containing 8 | 3.72822 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.58185 |
| NOSIP | nitric oxide synthase interacting protein | 3.05957 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 3.01164 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.99857 |
| LOC122526780 | uncharacterized LOC122526780 | 2.93693 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 2.87912 |
| TPK1 | thiamin pyrophosphokinase 1 | 2.85489 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.604 |
| UBQLN2 | ubiquilin 2 | 2.59721 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.54277 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.49785 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.38523 |
| PCDHB11 | protocadherin beta 11 | 2.35946 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.35038 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 2.27088 |
| CEP57 | centrosomal protein 57kDa | 2.24796 |
| PRR15L | proline rich 15-like | 2.20432 |
| NENF | neudesin neurotrophic factor | 2.17802 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.16629 |
| LIM2 | lens intrinsic membrane protein 2, 19kDa | 2.11727 |
| ATP5IF1 | ATP synthase inhibitory factor subunit 1 | 2.08602 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 2.04589 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 2.03521 |
| TUBB6 | tubulin, beta 6 class V | 2.02966 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -7.55917 |
| CD320 | CD320 molecule | -6.14304 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.03404 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -4.56587 |
| COG2 | component of oligomeric golgi complex 2 | -4.21221 |
| SCAND1 | SCAN domain containing 1 | -4.1161 |
| CHMP4B | charged multivesicular body protein 4B | -3.85637 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.75346 |
| ADI1 | acireductone dioxygenase 1 | -3.69635 |
| EGF | epidermal growth factor | -3.65467 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.63305 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.43055 |
| ZW10 | zw10 kinetochore protein | -3.36477 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.29213 |
| CSK | c-src tyrosine kinase | -3.22619 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.16405 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -3.08877 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -3.03843 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -3.00429 |
| CTSD | cathepsin D | -2.98841 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -2.85638 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.5567 |
| TLCD3A | TLC domain containing 3A | -2.51394 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.46364 |
| TOR1A | torsin family 1, member A (torsin A) | -2.37652 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.13823 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -2.09746 |
| CCNB1 | cyclin B1 | -2.08394 |
