| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | kepone 2.46 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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73 genes differentially expressed following the CRCGN009_HEPG2_24H:F23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 4.64798 |
| BLMH | bleomycin hydrolase | 4.53676 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.47996 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.42704 |
| TBPL1 | TBP-like 1 | 4.40638 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 4.38423 |
| MEST | mesoderm specific transcript | 4.31212 |
| PLSCR1 | phospholipid scramblase 1 | 4.25909 |
| PLS1 | plastin 1 | 4.19701 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.18612 |
| STIMATE | STIM activating enhancer | 4.09517 |
| TRIM13 | tripartite motif containing 13 | 3.48548 |
| NOSIP | nitric oxide synthase interacting protein | 3.4205 |
| SOCS2 | suppressor of cytokine signaling 2 | 3.3486 |
| KDM5A | lysine (K)-specific demethylase 5A | 3.13585 |
| PRR15L | proline rich 15-like | 3.00412 |
| GATA3 | GATA binding protein 3 | 2.79351 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.76226 |
| TBC1D31 | TBC1 domain family, member 31 | 2.6951 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 2.43659 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 2.36467 |
| GIMAP4 | GTPase, IMAP family member 4 | 2.34556 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.33743 |
| CISD1 | CDGSH iron sulfur domain 1 | 2.30682 |
| TENT4A | terminal nucleotidyltransferase 4A | 2.28714 |
| NLRP4 | NLR family, pyrin domain containing 4 | 2.246 |
| GPATCH8 | G patch domain containing 8 | 2.2453 |
| GATA2 | GATA binding protein 2 | 2.24482 |
| RAI14 | retinoic acid induced 14 | 2.23965 |
| LPAR6 | lysophosphatidic acid receptor 6 | 2.13007 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 2.12357 |
| NOTCH4 | notch 4 | 2.10285 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.09252 |
| RB1 | retinoblastoma 1 | 2.07808 |
| PMM2 | phosphomannomutase 2 | 2.02644 |
| CLEC7A | C-type lectin domain family 7, member A | 2.01554 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -5.14283 |
| KDM3A | lysine (K)-specific demethylase 3A | -5.13227 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -5.01633 |
| VAT1 | vesicle amine transport 1 | -4.88209 |
| COG2 | component of oligomeric golgi complex 2 | -4.53195 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.41688 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -4.12205 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.96801 |
| DERA | deoxyribose-phosphate aldolase (putative) | -3.92108 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.34026 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -3.29121 |
| VDAC1 | voltage-dependent anion channel 1 | -3.25983 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.04717 |
| SLC35F2 | solute carrier family 35, member F2 | -2.9583 |
| TMEM147 | transmembrane protein 147 | -2.91937 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -2.86225 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.81767 |
| TBCB | tubulin folding cofactor B | -2.68113 |
| CAPNS1 | calpain, small subunit 1 | -2.66158 |
| PRPF4 | pre-mRNA processing factor 4 | -2.61429 |
| GPATCH1 | G patch domain containing 1 | -2.57801 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -2.49518 |
| ZNF146 | zinc finger protein 146 | -2.44564 |
| UBE3C | ubiquitin protein ligase E3C | -2.44241 |
| RNF167 | ring finger protein 167 | -2.23969 |
| ZNF586 | zinc finger protein 586 | -2.21776 |
| DCK | deoxycytidine kinase | -2.21277 |
| FASTKD5 | FAST kinase domains 5 | -2.20703 |
| CCDC85C | coiled-coil domain containing 85C | -2.18965 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.18509 |
| SDHAF1 | succinate dehydrogenase complex assembly factor 1 | -2.16863 |
| DSN1 | DSN1, MIS12 kinetochore complex component | -2.14739 |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | -2.09807 |
| NVL | nuclear VCP-like | -2.09408 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.07441 |
| TMEM38B | transmembrane protein 38B | -2.06001 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.03625 |
