CRCGN009_HEPG2_24H:F24 Gene Set
Genes
33 genes differentially expressed following the CRCGN009_HEPG2_24H:F24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
6.49761
|
|
CCDC92
|
coiled-coil domain containing 92
|
4.2849
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.94918
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.93408
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.91053
|
|
LCN2
|
lipocalin 2
|
3.83672
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
3.82592
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.63209
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.61611
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.53642
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.4726
|
|
RPL39L
|
ribosomal protein L39-like
|
3.47044
|
|
MSRA
|
methionine sulfoxide reductase A
|
3.29191
|
|
MAP7
|
microtubule-associated protein 7
|
2.58363
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.50246
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-7.57429
|
|
LDHD
|
lactate dehydrogenase D
|
-6.01211
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-5.84908
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.78925
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.66313
|
|
CD320
|
CD320 molecule
|
-3.64395
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.42497
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.41399
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.35463
|
|
GNAS
|
GNAS complex locus
|
-3.06015
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.71005
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.68902
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.46459
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.3968
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.36503
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.24863
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.17425
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.15517
|
