| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | mepyramine 19.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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69 genes differentially expressed following the CRCGN009_HEPG2_24H:G02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 6.77891 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.48437 |
| GPER1 | G protein-coupled estrogen receptor 1 | 5.10442 |
| GPATCH8 | G patch domain containing 8 | 4.90074 |
| CHMP6 | charged multivesicular body protein 6 | 4.55396 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 4.50269 |
| AXIN1 | axin 1 | 4.30362 |
| MYLK | myosin light chain kinase | 4.24891 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.08981 |
| E2F2 | E2F transcription factor 2 | 4.02832 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.84261 |
| FZD7 | frizzled class receptor 7 | 3.55252 |
| OXCT1 | 3-oxoacid CoA transferase 1 | 3.32593 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 3.19207 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.10979 |
| PLSCR1 | phospholipid scramblase 1 | 3.06761 |
| MEST | mesoderm specific transcript | 3.01415 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.95231 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.88844 |
| PFKL | phosphofructokinase, liver | 2.87983 |
| SFTPB | surfactant protein B | 2.68073 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 2.67945 |
| TRAM2 | translocation associated membrane protein 2 | 2.5988 |
| EVL | Enah/Vasp-like | 2.54712 |
| ECD | ecdysoneless homolog (Drosophila) | 2.51135 |
| GATD3 | glutamine amidotransferase class 1 domain containing 3 | 2.50473 |
| NOSIP | nitric oxide synthase interacting protein | 2.30142 |
| FCHO1 | FCH domain only 1 | 2.20339 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 2.1936 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 2.18821 |
| SCRN1 | secernin 1 | 2.08816 |
| PARP1 | poly (ADP-ribose) polymerase 1 | 2.03995 |
| CRYZL1 | crystallin, zeta (quinone reductase)-like 1 | 2.02514 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FASTKD5 | FAST kinase domains 5 | -5.73259 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.70221 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.04607 |
| CDC20 | cell division cycle 20 | -4.9648 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.90025 |
| NGRN | neugrin, neurite outgrowth associated | -4.80872 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -4.72819 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -4.55343 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.288 |
| PCNA | proliferating cell nuclear antigen | -4.08517 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.99943 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.87755 |
| ADI1 | acireductone dioxygenase 1 | -3.69176 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -3.59478 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.47585 |
| CCNB2 | cyclin B2 | -3.45717 |
| WASHC4 | WASH complex subunit 4 | -3.26093 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.23472 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.99944 |
| SLC35F2 | solute carrier family 35, member F2 | -2.97563 |
| EGF | epidermal growth factor | -2.87333 |
| RNF167 | ring finger protein 167 | -2.86184 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.62395 |
| GTPBP8 | GTP-binding protein 8 (putative) | -2.60478 |
| TEX30 | testis expressed 30 | -2.47113 |
| PRAF2 | PRA1 domain family, member 2 | -2.26271 |
| CRYZ | crystallin, zeta (quinone reductase) | -2.26092 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -2.22882 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.22311 |
| GOLT1B | golgi transport 1B | -2.21539 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -2.15472 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | -2.13768 |
| DUSP4 | dual specificity phosphatase 4 | -2.03375 |
| PPY | pancreatic polypeptide | -2.01883 |
| UBE3C | ubiquitin protein ligase E3C | -2.01636 |
| PEX3 | peroxisomal biogenesis factor 3 | -2.01376 |
