| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | mepyramine 9.9 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
72 genes differentially expressed following the CRCGN009_HEPG2_24H:G03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 8.04231 |
| MAP7 | microtubule-associated protein 7 | 5.14327 |
| LPAR2 | lysophosphatidic acid receptor 2 | 4.58192 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.50811 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.39852 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.36979 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 4.29194 |
| E2F2 | E2F transcription factor 2 | 4.25685 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.74494 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.50435 |
| LCN2 | lipocalin 2 | 3.4821 |
| PNKP | polynucleotide kinase 3'-phosphatase | 3.47873 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.43114 |
| EPN2 | epsin 2 | 3.40594 |
| PRKCH | protein kinase C, eta | 3.25492 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.19304 |
| MOK | MOK protein kinase | 3.18041 |
| PFKL | phosphofructokinase, liver | 3.13404 |
| HEBP1 | heme binding protein 1 | 3.07564 |
| NOTCH1 | notch 1 | 3.0442 |
| EPHB2 | EPH receptor B2 | 3.02536 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.00157 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.64793 |
| CBR3 | carbonyl reductase 3 | 2.56101 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.40651 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.34137 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.33351 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) | 2.28299 |
| SATB1 | SATB homeobox 1 | 2.28179 |
| RPL39L | ribosomal protein L39-like | 2.26906 |
| S1PR4 | sphingosine-1-phosphate receptor 4 | 2.23184 |
| CHN1 | chimerin 1 | 2.21562 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.19289 |
| CORO1A | coronin, actin binding protein, 1A | 2.1709 |
| PSPN | persephin | 2.13405 |
| TRAF5 | TNF receptor-associated factor 5 | 2.10674 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.08193 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific | 2.07719 |
| CCDC106 | coiled-coil domain containing 106 | 2.07676 |
| EPHA3 | EPH receptor A3 | 2.04213 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.02497 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADI1 | acireductone dioxygenase 1 | -7.97577 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -7.95306 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -4.8574 |
| TLR4 | toll-like receptor 4 | -4.70913 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.63674 |
| CCNB1 | cyclin B1 | -4.50402 |
| LDHD | lactate dehydrogenase D | -4.37365 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.35284 |
| NGRN | neugrin, neurite outgrowth associated | -3.79979 |
| PCNA | proliferating cell nuclear antigen | -3.70551 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.40165 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.27161 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -3.23844 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.15661 |
| GNAS | GNAS complex locus | -2.8888 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.88591 |
| BCL6 | B-cell CLL/lymphoma 6 | -2.87552 |
| CCNB2 | cyclin B2 | -2.69374 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -2.6561 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.61675 |
| TXNRD1 | thioredoxin reductase 1 | -2.57864 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.54325 |
| TRAPPC6A | trafficking protein particle complex 6A | -2.53248 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -2.52375 |
| RGS2 | regulator of G-protein signaling 2 | -2.40758 |
| ILK | integrin-linked kinase | -2.20156 |
| AHR | aryl hydrocarbon receptor | -2.12672 |
| BIRC2 | baculoviral IAP repeat containing 2 | -2.09791 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.08394 |
| RBM7 | RNA binding motif protein 7 | -2.07301 |
| TSPAN31 | tetraspanin 31 | -2.01835 |
