| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | mepyramine 4.95 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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89 genes differentially expressed following the CRCGN009_HEPG2_24H:G04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 8.90241 |
| CBR3 | carbonyl reductase 3 | 8.06283 |
| EPHB2 | EPH receptor B2 | 5.15936 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 4.84105 |
| MSRA | methionine sulfoxide reductase A | 4.5092 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.43751 |
| DIPK1A | divergent protein kinase domain 1A | 4.35489 |
| STAP2 | signal transducing adaptor family member 2 | 4.26936 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.25582 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 4.20498 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.11248 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.10781 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.06104 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.94099 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 3.87774 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.81359 |
| STIMATE | STIM activating enhancer | 3.5431 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 3.51625 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.40937 |
| EVL | Enah/Vasp-like | 3.23604 |
| SMIM40 | small integral membrane protein 40 | 3.16035 |
| MCM3 | minichromosome maintenance complex component 3 | 3.06229 |
| THAP7 | THAP domain containing 7 | 2.82441 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.80621 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 2.78757 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.78504 |
| TBXA2R | thromboxane A2 receptor | 2.77253 |
| PRR15L | proline rich 15-like | 2.64937 |
| USP18 | ubiquitin specific peptidase 18 | 2.50746 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 2.50263 |
| THAP4 | THAP domain containing 4 | 2.39215 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 2.36612 |
| GRB10 | growth factor receptor-bound protein 10 | 2.35605 |
| NUBP2 | nucleotide binding protein 2 | 2.28264 |
| IRS1 | insulin receptor substrate 1 | 2.21312 |
| POU4F1 | POU class 4 homeobox 1 | 2.19696 |
| RUBCNL | rubicon like autophagy enhancer | 2.14228 |
| CCL24 | chemokine (C-C motif) ligand 24 | 2.1369 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.13684 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.10482 |
| CDX1 | caudal type homeobox 1 | 2.09867 |
| BCL2L14 | BCL2-like 14 (apoptosis facilitator) | 2.06999 |
| SDF2L1 | stromal cell-derived factor 2-like 1 | 2.00947 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | -7.42505 |
| GNAS | GNAS complex locus | -6.71485 |
| DNM1L | dynamin 1-like | -5.65701 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.38304 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.37608 |
| PCNA | proliferating cell nuclear antigen | -4.44011 |
| PEG10 | paternally expressed 10 | -4.22427 |
| TP53BP2 | tumor protein p53 binding protein 2 | -4.11794 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.94233 |
| CCNB2 | cyclin B2 | -3.81611 |
| CSK | c-src tyrosine kinase | -3.55724 |
| TLR4 | toll-like receptor 4 | -3.29236 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -3.10304 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.95325 |
| ZNF329 | zinc finger protein 329 | -2.92853 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -2.76193 |
| ZNF134 | zinc finger protein 134 | -2.66319 |
| ZNF813 | zinc finger protein 813 | -2.60982 |
| ZNF667 | zinc finger protein 667 | -2.55291 |
| DUSP10 | dual specificity phosphatase 10 | -2.50818 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.46039 |
| TCTN1 | tectonic family member 1 | -2.44599 |
| MAP9 | microtubule-associated protein 9 | -2.43243 |
| WASF1 | WAS protein family, member 1 | -2.37544 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -2.2922 |
| RPL9 | ribosomal protein L9 | -2.2722 |
| ARL17B | ADP-ribosylation factor-like 17B | -2.27077 |
| ZNF606 | zinc finger protein 606 | -2.27031 |
| ZNF669 | zinc finger protein 669 | -2.24575 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.24372 |
| DOCK1 | dedicator of cytokinesis 1 | -2.23318 |
| ZNF587B | zinc finger protein 587B | -2.22646 |
| ZNF415 | zinc finger protein 415 | -2.17078 |
| GTF2H2C | GTF2H2 family member C | -2.15417 |
| RNF139 | ring finger protein 139 | -2.13232 |
| CTSV | cathepsin V | -2.0969 |
| ZNF551 | zinc finger protein 551 | -2.09056 |
| BEX4 | brain expressed, X-linked 4 | -2.07882 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -2.06341 |
| ZNF419 | zinc finger protein 419 | -2.05943 |
| ZNF529 | zinc finger protein 529 | -2.03317 |
| TRIAP1 | TP53 regulated inhibitor of apoptosis 1 | -2.02866 |
| ELOVL6 | ELOVL fatty acid elongase 6 | -2.02713 |
| ZNF211 | zinc finger protein 211 | -2.02103 |
| LOC122539214 | Zinc finger protein LOC122539214 | -2.01872 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | -2.00625 |
