| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | mepyramine 2.48 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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81 genes differentially expressed following the CRCGN009_HEPG2_24H:G05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PNKP | polynucleotide kinase 3'-phosphatase | 7.47762 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 5.41185 |
| CYCS | cytochrome c, somatic | 5.29513 |
| PFKL | phosphofructokinase, liver | 5.0688 |
| SQOR | sulfide quinone oxidoreductase | 4.87465 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 4.76553 |
| UBQLN2 | ubiquilin 2 | 4.76114 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 4.37173 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.9572 |
| ABHD6 | abhydrolase domain containing 6 | 3.73612 |
| GATD3 | glutamine amidotransferase class 1 domain containing 3 | 3.4873 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.02296 |
| IL2RG | interleukin 2 receptor, gamma | 2.82921 |
| LOC122526780 | uncharacterized LOC122526780 | 2.79172 |
| MMP1 | matrix metallopeptidase 1 | 2.63296 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.5768 |
| GATA3 | GATA binding protein 3 | 2.53149 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 2.52324 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.48946 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 2.47489 |
| IL1R2 | interleukin 1 receptor, type II | 2.47181 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.4072 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) | 2.35726 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 2.35103 |
| SFTPB | surfactant protein B | 2.34635 |
| KNTC1 | kinetochore associated 1 | 2.32307 |
| MTREX | Mtr4 exosome RNA helicase | 2.29108 |
| CHEK2 | checkpoint kinase 2 | 2.24543 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 2.23855 |
| MYLK | myosin light chain kinase | 2.22943 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 2.22459 |
| SATB1 | SATB homeobox 1 | 2.20569 |
| TRAPPC10 | trafficking protein particle complex 10 | 2.16424 |
| KIFAP3 | kinesin-associated protein 3 | 2.12548 |
| TEX10 | testis expressed 10 | 2.1254 |
| SELENOW | selenoprotein W | 2.11072 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 2.09425 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 2.07761 |
| CHP2 | calcineurin-like EF-hand protein 2 | 2.07377 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | 2.0724 |
| TXNIP | thioredoxin interacting protein | 2.05982 |
| PIGR | polymeric immunoglobulin receptor | 2.04856 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | 2.03545 |
| MMP3 | matrix metallopeptidase 3 | 2.02026 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -7.06816 |
| PLK1 | polo-like kinase 1 | -4.77198 |
| TP53BP2 | tumor protein p53 binding protein 2 | -4.68586 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.55821 |
| COG2 | component of oligomeric golgi complex 2 | -4.5083 |
| PUF60 | poly-U binding splicing factor 60KDa | -4.45599 |
| PEG10 | paternally expressed 10 | -4.43226 |
| TLCD3A | TLC domain containing 3A | -4.30093 |
| SNX11 | sorting nexin 11 | -3.49189 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -3.35237 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.14507 |
| ZNF586 | zinc finger protein 586 | -3.13117 |
| DNM1L | dynamin 1-like | -3.0887 |
| CSK | c-src tyrosine kinase | -3.07612 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -3.05623 |
| TXNDC9 | thioredoxin domain containing 9 | -3.04713 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.90219 |
| BCAS4 | breast carcinoma amplified sequence 4 | -2.86704 |
| PNPLA3 | patatin-like phospholipase domain containing 3 | -2.70522 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.59149 |
| SCRIB | scribbled planar cell polarity protein | -2.45997 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.41341 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -2.368 |
| MVP | major vault protein | -2.36666 |
| THEM6 | thioesterase superfamily member 6 | -2.33345 |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 | -2.30901 |
| GNAS | GNAS complex locus | -2.30497 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -2.28578 |
| SLC52A2 | solute carrier family 52 (riboflavin transporter), member 2 | -2.19665 |
| YAF2 | YY1 associated factor 2 | -2.18652 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.16043 |
| ANXA9 | annexin A9 | -2.10694 |
| CERS2 | ceramide synthase 2 | -2.09113 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -2.07417 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | -2.05771 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -2.0291 |
| TNFAIP8L2-SCNM1 | TNFAIP8L2-SCNM1 readthrough | -2.01252 |
