| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | mepyramine 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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101 genes differentially expressed following the CRCGN009_HEPG2_24H:G06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 9.43082 |
| MAP7 | microtubule-associated protein 7 | 7.26882 |
| AMDHD2 | amidohydrolase domain containing 2 | 5.39389 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.2108 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 5.13769 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.07616 |
| SQOR | sulfide quinone oxidoreductase | 4.99645 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 4.77805 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 4.75445 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 4.57477 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.34073 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.22977 |
| HDGFL3 | HDGF like 3 | 3.93299 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.90201 |
| CYCS | cytochrome c, somatic | 3.79993 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.50766 |
| TESK1 | testis-specific kinase 1 | 3.46857 |
| LRRC31 | leucine rich repeat containing 31 | 3.29578 |
| FZD7 | frizzled class receptor 7 | 3.28456 |
| RXYLT1 | ribitol xylosyltransferase 1 | 3.18922 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 3.17937 |
| NOSIP | nitric oxide synthase interacting protein | 3.05605 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.61178 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.59605 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.57279 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.5044 |
| CREB3L4 | cAMP responsive element binding protein 3-like 4 | 2.49312 |
| CHEK2 | checkpoint kinase 2 | 2.44195 |
| GATA2 | GATA binding protein 2 | 2.42176 |
| HOXC6 | homeobox C6 | 2.39593 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.38987 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.38532 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.35412 |
| PPP2R2D | protein phosphatase 2, regulatory subunit B, delta | 2.34966 |
| DIPK1A | divergent protein kinase domain 1A | 2.33905 |
| EVL | Enah/Vasp-like | 2.27447 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.24255 |
| A1CF | APOBEC1 complementation factor | 2.22079 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 2.20297 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.17152 |
| NUBP2 | nucleotide binding protein 2 | 2.15732 |
| CLDN15 | claudin 15 | 2.14231 |
| DPP4 | dipeptidyl-peptidase 4 | 2.13595 |
| MAGEC2 | melanoma antigen family C2 | 2.12821 |
| LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 | 2.10409 |
| LMF2 | lipase maturation factor 2 | 2.10317 |
| GATA4 | GATA binding protein 4 | 2.09556 |
| RAP2A | RAP2A, member of RAS oncogene family | 2.0822 |
| ANKRD44 | ankyrin repeat domain 44 | 2.07123 |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 | 2.05914 |
| PRB2 | proline-rich protein BstNI subfamily 2 | 2.05406 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.03843 |
| HAND1 | heart and neural crest derivatives expressed 1 | 2.03486 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.02083 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -9.44824 |
| CCNB2 | cyclin B2 | -7.16112 |
| FGFR4 | fibroblast growth factor receptor 4 | -7.10221 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.26429 |
| COG2 | component of oligomeric golgi complex 2 | -5.02654 |
| CD320 | CD320 molecule | -4.9242 |
| PCNA | proliferating cell nuclear antigen | -4.68482 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.67676 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -4.65588 |
| CDC20 | cell division cycle 20 | -4.51949 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.50217 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.43253 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -4.33292 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.3308 |
| NCK1 | NCK adaptor protein 1 | -4.30208 |
| NGRN | neugrin, neurite outgrowth associated | -4.25057 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -4.09015 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -4.08582 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.79392 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -3.52925 |
| GNAS | GNAS complex locus | -3.29931 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.25798 |
| PRPF4 | pre-mRNA processing factor 4 | -3.219 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -3.16455 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -3.07539 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.0705 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -3.01966 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -2.80251 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.5766 |
| POMZP3 | POM121 and ZP3 fusion | -2.402 |
| OSBPL9 | oxysterol binding protein-like 9 | -2.3722 |
| KYAT3 | kynurenine aminotransferase 3 | -2.28515 |
| HMG20B | high mobility group 20B | -2.2347 |
| SLBP | stem-loop binding protein | -2.18654 |
| RNF167 | ring finger protein 167 | -2.17808 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.1441 |
| ATP5F1D | ATP synthase F1 subunit delta | -2.12983 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.11868 |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.06907 |
| GLOD4 | glyoxalase domain containing 4 | -2.06779 |
| TBCB | tubulin folding cofactor B | -2.06394 |
| LAMA5 | laminin, alpha 5 | -2.04958 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 | -2.04595 |
| POLR2J3 | polymerase (RNA) II (DNA directed) polypeptide J3 | -2.01724 |
| TMEM231 | transmembrane protein 231 | -2.00818 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | -2.00779 |
| TSPYL4 | TSPY-like 4 | -2.00536 |
