CRCGN009_HEPG2_24H:G09 Gene Set
Genes
59 genes differentially expressed following the CRCGN009_HEPG2_24H:G09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
7.70296
|
|
MYLK
|
myosin light chain kinase
|
7.49785
|
|
LCN2
|
lipocalin 2
|
7.45608
|
|
UBQLN2
|
ubiquilin 2
|
5.21328
|
|
STIMATE
|
STIM activating enhancer
|
4.46437
|
|
EPHB2
|
EPH receptor B2
|
4.23175
|
|
CCNF
|
cyclin F
|
4.1911
|
|
NOTCH1
|
notch 1
|
4.12541
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.67031
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.55418
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.42032
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.36307
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.22185
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.18008
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.10098
|
|
EAPP
|
E2F-associated phosphoprotein
|
3.0289
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.90653
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.70499
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.6434
|
|
VAT1
|
vesicle amine transport 1
|
2.48253
|
|
FHIT
|
fragile histidine triad
|
2.46783
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.45105
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
2.30364
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.23547
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.19578
|
|
FPGS
|
folylpolyglutamate synthase
|
2.18533
|
|
ADAM10
|
ADAM metallopeptidase domain 10
|
2.13235
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.09046
|
|
CYCS
|
cytochrome c, somatic
|
2.02242
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-7.49228
|
|
PCNA
|
proliferating cell nuclear antigen
|
-6.73822
|
|
ZNF586
|
zinc finger protein 586
|
-6.56734
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-6.26954
|
|
DNM1L
|
dynamin 1-like
|
-4.63465
|
|
GOLT1B
|
golgi transport 1B
|
-4.59142
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.57399
|
|
TLR4
|
toll-like receptor 4
|
-4.19414
|
|
DSG2
|
desmoglein 2
|
-3.80139
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.79205
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.49399
|
|
CAB39
|
calcium binding protein 39
|
-3.35438
|
|
NVL
|
nuclear VCP-like
|
-3.13035
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.88028
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.53729
|
|
TCERG1
|
transcription elongation regulator 1
|
-2.4393
|
|
PEG10
|
paternally expressed 10
|
-2.43136
|
|
RNF167
|
ring finger protein 167
|
-2.39967
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.39029
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-2.37585
|
|
GNAS
|
GNAS complex locus
|
-2.30643
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.23988
|
|
DEGS1
|
delta(4)-desaturase, sphingolipid 1
|
-2.14797
|
|
LDHD
|
lactate dehydrogenase D
|
-2.14154
|
|
CD58
|
CD58 molecule
|
-2.12967
|
|
MNT
|
MAX network transcriptional repressor
|
-2.11098
|
|
MCF2L
|
MCF.2 cell line derived transforming sequence-like
|
-2.10596
|
|
PPFIBP2
|
PTPRF interacting protein, binding protein 2 (liprin beta 2)
|
-2.07073
|
|
PYCARD
|
PYD and CARD domain containing
|
-2.00886
|
|
ZNF134
|
zinc finger protein 134
|
-2.0067
|
