CRCGN009_HEPG2_24H:G10 Gene Set
Genes
33 genes differentially expressed following the CRCGN009_HEPG2_24H:G10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
6.50442
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.67048
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
5.07331
|
|
LCN2
|
lipocalin 2
|
5.0
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.94894
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.4707
|
|
STK10
|
serine/threonine kinase 10
|
4.36269
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.63609
|
|
CORO1A
|
coronin, actin binding protein, 1A
|
3.15313
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.09324
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.95966
|
|
CEP57
|
centrosomal protein 57kDa
|
2.87738
|
|
CCNF
|
cyclin F
|
2.71278
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.55733
|
|
CRTAP
|
cartilage associated protein
|
2.32269
|
|
CYCS
|
cytochrome c, somatic
|
2.21474
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.97612
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-4.9255
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.92156
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.81244
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.36767
|
|
CCNB2
|
cyclin B2
|
-3.39397
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-2.9437
|
|
CDC20
|
cell division cycle 20
|
-2.79015
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.78163
|
|
CPSF4
|
cleavage and polyadenylation specific factor 4, 30kDa
|
-2.75603
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.57494
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.48012
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
-2.46181
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.24823
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.12385
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.07988
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.04459
|
